A structure of aligned (e.g., radially and/or polygonally aligned) fibers, and systems and methods for producing and using the same. One or more structures provided may be created using an apparatus that includes one or more first electrodes that define an area and/or partially circumscribe an area. For example, a single first electrode may enclose the area, or a plurality of first electrode(s) may be positioned on at least a portion of the perimeter of the area. A second electrode is positioned within the area. Electrodes with rounded (e.g., convex) surfaces may be arranged in an array, and a fibrous structure created using such electrodes may include an array of wells at positions corresponding to the positions of the electrodes.

According to one embodiment, a nozzle head module includes a nozzle head having a hole electing a source material liquid, the nozzle head being configured to have a first voltage and an electrode provided to be relatively movable with respect to the nozzle head, the electrode being configured to have a second voltage. The second voltage is of the same polarity as the first voltage.

According to one embodiment, a fiber sheet includes a plurality of fibers. The plurality of fibers are in a closely-adhered state.

All of the following (1) to (3) are satisfied, where F1 is a tensile strength in a first direction, and F2 is a tensile strength in a second direction orthogonal to the first direction: (1) F2>F1; (2) F1 is 1 MPa or more; and (3) F2/F1 is 2 or more.

According to one embodiment, a nozzle head includes a main body and a plurality of nozzles. The main body has a space in an interior of the main body. The space is capable of storing a source material liquid. The plurality of nozzles are conductive, are connected to the main body, and eject the source material liquid stored in the interior of the main body. An external dimension of one of the nozzles in a direction orthogonal to an extension direction of the nozzle is different from the external dimension of another one of the nozzles in the direction orthogonal to the extension direction of the nozzle.

A nozzle for an electrospinning spinneret, the nozzle including a material transporting channel having a wall that has an end surface for forming a droplet, and an electrode extending through the material transporting channel at least up to the end surface of the wall.

An electrospinning device is for manufacturing material that includes aligned nano-fibers. The device includes a rotor and more than one electrically conducting protrusions disposed on the surface of the rotor and spaced apart from one another. The protrusions are configured such that an electrostatic field created when a potential difference is applied between the rotor and a target is concentrated at the tips of the protrusions and decreases between neighboring protrusions.

An applicator is disclosed for applying a treatment solution to a treatment site of a patient. The applicator can include an applicator housing comprising a treatment solution reservoir. A cartridge can be removably disposed in the housing. The cartridge when arranged in the housing can be in fluid communication with the treatment solution reservoir. The cartridge can include an electrostatic module for electrostatically charging the treatment solution in the treatment solution reservoir; and a nozzle for applying the treatment solution.

A method for controlling fiber cross-alignment in a nanofiber membrane, comprising: providing a multiple segment collector in an electrospinning device including a first and second segment electrically isolated from an intermediate segment positioned between the first and second segment, collectively presenting a cylindrical structure, rotating the cylindrical structure around a longitudinal axis proximate to an electrically charged fiber emitter; electrically grounding or charging edge conductors circumferentially resident on the first and second segment, maintaining intermediate collector electrically neutral; dispensing electrospun fiber toward the collector, the fiber attaching to edge conductors and spanning the separation space between edge conductors; attracting electrospun fiber attached to the edge conductors to the surface of the cylindrical structure, forming a first fiber layer; increasing or decreasing rotation speed of the cylindrical structure to alter the angular cross-alignment relationship between aligned nanofibers in adjacent layers, the rotation speed being altered to achieve a target relational angle.

Device for the production of nanofibrous and/or microfibrous layers having an increased thickness uniformity by spinning a liquid material (3), said device comprising: a collecting electrode (6), a spinning nozzle (1) for dispensing the liquid material (3) to be spun, an assembly for guiding the collecting electrode (6) and/or for guiding a base strip (5) along the collecting electrode (6) or adjacent to it, such that—in the area faced by the outlet orifice (10) of the spinning nozzle (1)—the collecting electrode (6) and/or the base strip (5) move(s) in the direction (MD) spaced from the outlet orifice (10) of the spinning nozzle (1), a power supply for generating a voltage of 10 to 150 kV between the collecting electrode (6) and the spinning nozzle (1), at least one body (2), which moves along the liquid surface to destabilize the locations of the points where fibres (4) are formed on the surface of the liquid material (3) at the outlet orifice (10) of the spinning nozzle (1). The nanofibrous and/or microfibrous layers having an increased thickness uniformity are produced by spinning a liquid material (3) in an electrostatic field, wherein a body (2) is moved along the surface of the spun liquid in order to destabilize positions of locations, where the fibers originate.

The present invention falls within the area of polymeric materials based on ultrafine fibres for use in the pharmaceutical, nutraceutical and cosmetic sector, relating to the method of producing self-adhesive patches and the use thereof as a platform for the controlled release of bioactives by means of electrohydrodynamic and/or aerohydrodynamic processing techniques.