A phosphonate salt for use in a dental treatment, in particular in a root canal treatment, for the manufacture of a pharmaceutical preparation, in particular as decalcifying agent and a pharmaceutical preparation for use in the dental treatment comprising a phosphonate salt and/or a phosphonate salt and a hydroxide compound in solid form are provided. A method of producing a pharmaceutical preparation and a kit of parts for manufacturing a pharmaceutical preparation for use in the dental treatment are provided.

A method of reducing an inflammation of a pulp or a periodontal ligament, said method comprising the steps of: (a) removing material from a pulp cavity and/or a root canal of a tooth; (b) rinsing pulp chamber with an anti-inflammatory rinse solution, (c) irrigating the root canal with an anti-inflammatory rinse solution to remove residual bacteria and/or smear layer, (d) providing an anti-inflammatory filling composition comprising: (i) at least 80% by weight of a premixed cement putty, said cement putty including at least one calcium silicate compound in the range of about 30% to about 90% by weight of said putty; and at least about 1% to about 50% of a liquid carrier including a water-soluble polymer and/or water-soluble oil; and (ii) about 3 to about 15% by weight of an anti-inflammatory agent, the anti-inflammatory agent including eugenol, vitamin E or mixtures thereof, and (e) introducing the anti-inflammatory filling composition into the cavity and/or root canal and allow the composition to harden.

Provided is a dental pretreatment material for dental tissue regeneration by use of dental pulp stem cells, particularly a dental pretreatment material effectively enabling dental tissue regeneration even by use of dental pulp stem cells of middle-aged or older individuals. The dental pretreatment material is characterized by comprising a serine protease, specifically trypsin. The dental pretreatment material comprising trypsin is used as an injection into a root canal before a root canal filling material comprising dental pulp stem cells and an extracellular matrix is inserted into the root canal as an attempt to regenerate a dental pulp and a dentin. The root canal filling material includes an ALK5 inhibitor, a CCR3 antagonist, or a CCL11 neutralizing antibody.

The invention relates to a medical composition comprising guanidinyl-containing polymer(s) and polyanionic polymer(s). The medical composition is useful for absorbing water-containing fluids and can be used as dental retraction composition or as part of a medical treatment device.

A gutta-percha-silver composite with determined weight percentage and particle size, is provided. The composite exhibits electro-conductivity greater than the standard gutta-percha composites. The new material simplifies root canal treatments, shortens the times both for clinician and patients, and reduces the exposure to patients from X-rays. The material is not only electro-conductive; it is anti-bacterial, which improves the outcomes of the procedures. Also, it has improved thermal conductivity, and mechanical properties.

A method for continuously evaluating the effectiveness of debridement of a root canal of a tooth, the tooth having an open access cavity and an apex end, includes delivering a fluid to the open access cavity of the tooth, evacuating the fluid near the apex end of the tooth such that the fluid flushes most of the root canal before being evacuated, and continuously evaluating the evacuated fluid for at least one of a presence of debris, a concentration level of the debris, or a type of the debris. An apparatus for use in debriding a root canal of a tooth includes a microcannula or a macrocannula configured to evacuate a fluid in the root canal, and a sensing mechanism fluidically coupled to the microcannula or the macrocannula, the sensing mechanism configured to continuously sense debris in the evacuated fluid in real time.

Provided are methods of detecting tooth stain prevention and/or removal comprising the steps of providing pellicle-coated hydroxyapatite particles, contacting the particles with a first solution and then a second solution, wherein the first solution is either a test solution or a stain solution and the second solution is the other of said test solution or stain solution, separating from the resulting particles a liquid comprising stain introduced in the contacting step b), and measuring the UV-Vis absorbance of the separated liquid to determine the amount of stain in the liquid.

The invention relates to the application of photon energy to energize dental materials to enhance their physical handling characteristics, efficacy, ability to be delivered, reactivity, polymerization, and/or post-cure mechanical properties, among other attributes.

Dental and medical treatments and methods, including treating gum disease, using peroxide gel and a viscous antimicrobial including a topical antibacterial agent, a topical antiviral agent, a topical antibiotic, a topical antifungal agent, a topical antiseptic agent, or a topical anti-intermicrobial agent to chemically debride and curettage a treatment area. Treatments and methods include non-surgically scaling and root plaining the treatment area with dental tools such as periodontal scalers and/or curettes during the active period of the chemical debridement. The working surfaces of dental and medical tools can be sharpened for optimal root and tooth surfacing during treatment. Treatment can include instructions for co-therapy by or on behalf of treatment subjects between visits and for maintenance care.

A photosensitizer-containing dispersion, and use thereof.