A root canal irrigant, and particularly to a root canal irrigant comprising Rosa Damascena Mill.

Chitosan nanoparticles are provided for use in the in vivo treatment of connective tissues in root canal therapies. The nanoparticles are optionally linked with one or more photoactivatable compounds for providing antibactenal/antibiofilm properties, neutralizing bacterial byproducts and/or chemical/photodynamic crosslinking to achieve enhanced mechanical properties, chemical stability in connective tissues and/or to improve surface/interfacial integrity between filling material and connective tissue.

A photo-chemically activated micro-bubble based root canal disinfection method for disinfecting a shaped root canal comprises (a) introducing a photoactive solution into the root canal, the photoactive solution containing a photoactive compound (such as methylene blue) dissolved in an alcohol carrier solution (such as polyethylene glycol and/or ethanol); (b) removing excess photoactive solution from the root canal; (c) introducing a micro-bubble solution comprised of an oxygen carrier (such as perfluorocarbon), an oxidizing agent (such as hydrogen peroxide) and a surfactant (such as a nonionic polyoxyethylene surfactant); (d) sonically or ultrasonically activating the micro-bubble solution in the canal; and (e) introducing light into the canal.

Dental treatments and methods, including treating gum disease, using peroxide gel and a viscous antibacterial agent including tetracycline to chemically debride and curettage a treatment area. Treatments and methods include non-surgically scaling and root plaining the treatment area with dental tools such as periodontal scalers and/or curettes during the active period of the chemical debridement. The working surfaces of dental tools can be sharpened for optimal root and tooth surfacing during treatment. Treatment can include instructions for co-therapy by or on behalf of treatment subjects between visits and for maintenance care.

A root canal filling material for a tooth extraction or tooth non-extraction process can be used clinically because of its easy availability and can efficiently enhance dental tissue regeneration; a method for regenerating dental tissue using the filling material is also provided. A root canal filling material 200 including mesenchymal stem cells 220 excluding dental pulp stem cells, which are inserted into the apical side of a root canal subjected to pulp extirpation or to root canal enlargement and cleaning of an infected root canal and including an extracellular matrix 210 is provided, and a method for regenerating dental tissue, through a tooth extracting or tooth non-extracting process, including a step of injecting the root canal filling material into the apical side of a root canal of a non-extracted tooth subjected to pulp extirpation or to root canal enlargement and cleaning of an infected root canal is provided.

A method of direct pulp capping of a tooth including administering a dental composition comprising betamethasone and gentamicin onto an exposed pulp of a tooth, and covering the dental composition present on the tooth with a glass ionomer cement. The dental composition is administered in an amount effective to form a calcification over the exposed pulp. A dental composition having betamethasone, gentamicin, and optionally including a Portland cement. The dental composition is administered to an exposed pulp of a tooth to form a calcification over the exposed pulp.

A dental composition comprising: a) about 1 to about 80% by weight of particulate material including: (i) calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide, or mixtures thereof; wherein the particulate material has an average particle size of less than 40 microns; and b) about 1 to about 50% by weight liquid carrier including: (i) water-soluble polymer, and (ii) water.

A dental composition comprising: a) about 1 to about 80% by weight of particulate material including: (i) calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide, or mixtures thereof; wherein the particulate material has an average particle size of less than 40 microns; and b) about 1 to about 50% by weight liquid carrier including: (i) water-soluble polymer, and (ii) water.

A phosphonate salt for use in a dental treatment, in particular in a root canal treatment, for the manufacture of a pharmaceutical preparation, in particular as decalcifying agent and a pharmaceutical preparation for use in the dental treatment comprising a phosphonate salt and/or a phosphonate salt and a hydroxide compound in solid form are provided. A method of producing a pharmaceutical preparation and a kit of parts (1, 1) for manufacturing a pharmaceutical preparation for use in the dental treatment are provided.

The present invention relates to a dental implant (118) or an element thereof comprising a trans-mucosal portion (122), wherein at least a part of said trans-mucosal portion (122) comprises a biocide (132) and/or a pH regulator. Moreover, the present invention relates to methods for preventing biofilm formation on a trans-mucosal portion (122) of a dental implant (118) and for preventing or treating dental implant associated inflammation, comprising providing and implanting a dental implant (118) or an element thereof according to the present invention. The present invention further relates to the use of a biocide for manufacturing a dental implant (118) or element thereof, and to a biocide (132) released from a dental implant (118) or an element thereof according to the present invention for use in preventing and/or treating dental implant associated inflammation. Further the present invention relates to the use of a biocide for manufacturing denture teeth and/or denture resin.