A61K6/52

DENTAL PULP CAPPING COMPOSITION AND METHOD OF PRESERVING AND REGENERATING CAPPED PULP AND DENTIN BRIDGE

The invention relates to the application of a composition containing recombinant amelogenin and propylene glycol alginate (PGA) on to cut dentin tubules followed by installation of a definitive restorative in a single visit.

Method for Obtaining Functionalised Polymer Particles

The present invention relates to a precipitation polymerization method for obtaining spherical polymer particles of a copolymer with statistical topology and chemical structure (acid monomer selected from acrylic or methacrylic)-co-(cross-linker selected from acrylic or methacrylic)-co-(hydroxylated monomer selected from acrylic or methacrylic) and which are functionalised with a divalent cation selected from Zn.sup.+2, Ca.sup.+2, Mg.sup.+2 and Sr.sup.+2 and/or an antibacterial agent. The invention also relates to said polymeric particles. The invention further relates to a composition comprising the polymeric particles and to the use of the particles to produce a drug.

Composition and Method for Endodontic Debridement
20210022964 · 2021-01-28 ·

Provided herein are compositions and kits including trichloroacetic acid, and methods of using the same for debridement during endodontic treatment.

Endodontic point containing ultrasonic deformable material
10898295 · 2021-01-26 · ·

The endodontic point containing ultrasonic deformable material is a filler for root canal therapy that decreases in viscosity when subjected to ultrasonic waves. Once the point is inserted into a prepared tooth space, such as a prepared and cleaned root canal, the point is subjected to ultrasonic waves. The ultrasonic waves cause the viscosity of the point to lower, thus allowing the point to flow into voids in the tooth space and allow air to escape from the voids. The point then hardens and remains in the shape acquired when at low viscosity once application of the ultrasonic waves is stopped.

ANTISEPTIC AND/OR ANTI-INFLAMMATORY GEL FOR TREATMENT OF ORAL CAVITY DISEASES COMPRISING POLYVINYL ALCOHOL AND POLYACIDS
20210007983 · 2021-01-14 ·

Product for the therapeutic treatment for the prevention and cure of oral cavity diseases of teeth and dental implants including a mixture in a polyvinyl alcohol aqueous solution, of one or more polyacids or their salts, of one or more antiseptics and/or anti-inflammatories, capable of obtaining in situ a protective and adhesive barrier, capable of facilitating the bioavailability of the aforementioned medicinal products, antiseptics and anti-inflammatories.

NOVEL ENDODONTIC IRRIGANT
20240000669 · 2024-01-04 ·

A medicament for dental procedures includes a first component comprising an oxidizing agent, and a second component comprising a calcium complexing agent, wherein when the first component is mixed with the second component, the pH is greater than 6.2. Kits including the medicament and methods of use of the medicament are disclosed.

NOVEL ENDODONTIC IRRIGANT
20240000669 · 2024-01-04 ·

A medicament for dental procedures includes a first component comprising an oxidizing agent, and a second component comprising a calcium complexing agent, wherein when the first component is mixed with the second component, the pH is greater than 6.2. Kits including the medicament and methods of use of the medicament are disclosed.

PHOTOSENSITISING COMPOSITION AND USES THEREOF

The present invention provides a photosensitising composition comprising a mixture of at least one surfactant at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.

PHOTOSENSITISING COMPOSITION AND USES THEREOF

The present invention provides a photosensitising composition comprising a mixture of at least one surfactant at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.

REGENERATION OF VITAL TOOTH PULP

Methods of regenerating vital tooth tissue in situ after endodontic therapy include introducing a hydrogel scaffold into a root canal of a tooth in a patient after native pulp has been removed from the root canal. The hydrogel scaffold may comprise a sponge scaffold, and can be acellular. The hydrogel scaffold can contain chemotactic, angiogenic, neurogenic, and/or immunomodulatory biofactors that cause infiltration of endogenous cells from the patient into the root canal. Alternatively, such biofactors/drugs can be administered to the patient separately from the hydrogel scaffold. The hydrogel scaffold can fill the periapical space of an abscessed root.