The present invention discloses a new family of calcium sulfate resin-modified hybrid (CSRH) materials and methods of making and using the same.

The present invention discloses a new family of calcium sulfate resin-modified hybrid (CSRH) materials and methods of making and using the same.

A dental composition comprising a therapeutically effective amount of doxycycline hyclate and a therapeutically effective amount of triamcinolone acetonide and use in dental treatment.

The present invention relates to a dental implant (118) or an element thereof comprising a trans-mucosal portion (122), wherein at least a part of said trans-mucosal portion (122) comprises a biocide (132) and/or a pH regulator. Moreover, the present invention relates to methods for preventing biofilm formation on a trans-mucosal portion (122) of a dental implant (118) and for preventing or treating dental implant associated inflammation, comprising providing and implanting a dental implant (118) or an element thereof according to the present invention. The present invention further relates to the use of a biocide for manufacturing a dental implant (118) or element thereof, and to a biocide (132) released from a dental implant (118) or an element thereof according to the present invention for use in preventing and/or treating dental implant associated inflammation. Further the present invention relates to the use of a biocide for manufacturing denture teeth and/or denture resin.

Provided is a pharmaceutical composition excellent in capability of an accelerated penetration into an affected area. The pharmaceutical composition capable of accelerated penetration into the affected area is formed by dispersing nano-bubbles, which are negatively charged and are given high internal pressures due to their surface tension, in the pharmaceutical composition in a form of a liquid or a gel including a predetermined drug.

A strontium-doped root canal filling paste, a preparation method therefor and use thereof in the treatment of dental pulp disease are provided. The strontium-doped root canal filling paste includes a component (a) and a component (b), wherein component (a) is selected from calcium silicate compounds, and component (b) is selected from strontium compounds. Component (a) accounts for 20%-40% of by weight of the paste, and component (b) accounts for 0.5%-10% by weight of the paste; and components (a) and (b) are doped in a physical doping manner.

Proposed are a method of preparing new biomaterials for dental pulp regeneration and a composition of new biomaterials prepared accordingly. The composition of new biomaterials prepared according to the method of preparing new biomaterials for dental pulp regeneration by mixing a first precursor containing calcium silicate-based cement (CSC) at an appropriate concentration and a second precursor containing a secretome of dental pulp-derived mesenchymal stem cells in an appropriate ratio and then drying the resulting mixture under appropriate drying conditions is characterized by further improving the osteogenic differentiation ability of dental pulp stem cells compared to existing materials while maintaining the microhardness of the composition to an appropriate standard. In addition, the composition is advantageous in that an aesthetic effect is excellent by not causing tooth discoloration.

Proposed are a method of preparing new biomaterials for dental pulp regeneration and a composition of new biomaterials prepared accordingly. The composition of new biomaterials prepared according to the method of preparing new biomaterials for dental pulp regeneration by mixing a first precursor containing calcium silicate-based cement (CSC) at an appropriate concentration and a second precursor containing a secretome of dental pulp-derived mesenchymal stem cells in an appropriate ratio and then drying the resulting mixture under appropriate drying conditions is characterized by further improving the osteogenic differentiation ability of dental pulp stem cells compared to existing materials while maintaining the microhardness of the composition to an appropriate standard. In addition, the composition is advantageous in that an aesthetic effect is excellent by not causing tooth discoloration.