The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.

The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.

The present invention relates to an internal hole filler of an abutment for implant, which includes first polytetrafluoroethylene (first PTFE) and second polytetrafluoroethylene (second PTFE), wherein tensile strength measured after sintering the first PTFE is in a range of 20 MPa or more to less than 28 MPa, and tensile strength measured after sintering the second PTFE is 28 MPa or more, and a method of filling an internal hole of the abutment for implant.

The present invention relates to an internal hole filler of an abutment for implant, which includes first polytetrafluoroethylene (first PTFE) and second polytetrafluoroethylene (second PTFE), wherein tensile strength measured after sintering the first PTFE is in a range of 20 MPa or more to less than 28 MPa, and tensile strength measured after sintering the second PTFE is 28 MPa or more, and a method of filling an internal hole of the abutment for implant.

Techniques and devices including a biocompatible antibacterial film are provided. An example method for depositing a biocompatible antibacterial film using physical vapor deposition (PVD) includes providing a substrate in a PVD processing chamber, forming a deposited film by co-depositing a first material and a second material onto the substrate from a vapor plume, wherein at least the first material is biocompatible and at least the second material is antibacterial, and nano-texturing the deposited film to produce nano-scale surface asperities that provide at least one of inhibition of bacterial growth, promotion of osseointegration, promotion of epithelial attachment, or promotion of endothelial attachment.

Techniques and devices including a biocompatible antibacterial film are provided. An example method for depositing a biocompatible antibacterial film using physical vapor deposition (PVD) includes providing a substrate in a PVD processing chamber, forming a deposited film by co-depositing a first material and a second material onto the substrate from a vapor plume, wherein at least the first material is biocompatible and at least the second material is antibacterial, and nano-texturing the deposited film to produce nano-scale surface asperities that provide at least one of inhibition of bacterial growth, promotion of osseointegration, promotion of epithelial attachment, or promotion of endothelial attachment.

A method that includes applying a liquid pre-coloring solution to a gum section of a zirconia dental prosthesis, wherein the liquid pre-coloring solution comprises erbium in an amount of at least 10 wt %, based on the total weight of the composition.

A method that includes applying a liquid pre-coloring solution to a gum section of a zirconia dental prosthesis, wherein the liquid pre-coloring solution comprises erbium in an amount of at least 10 wt %, based on the total weight of the composition.

An approach is disclosed that involves creating an implant-supported prosthesis that is dynamically guided into position using an image-guided navigation system into position in a patient's mouth without the use of a surgical guide.

Methods and compositions are provided for enhancing dentin production, and for delivering a lipophilic agent to pulp tissue of a tooth of an individual. In some cases, a subject method includes a step of administering to the pulp of a tooth of an individual, a Wnt stimulating composition that includes a Wnt stimulator agent, at a dose sufficient to enhance the production of dentin by the pulp. In some cases, a subject method includes a step of contacting exposed dentin of a tooth with a composition that includes a lipophilic agent inserted in the non-aqueous phase of a lipid structure (e.g., whereby the lipophilic agent penetrates the dentin to the underlying pulp tissue). Kits are also provided for practicing the methods of the disclosure.