Patent classifications
A61K6/65
PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE
In one embodiment, the present application discloses a photo-cleavable surface binding compound of the Formula I and Formula II:
##STR00001##
wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound.
FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF
The present invention provides a dental curable composition that shows fluorescence sufficient to enable highly aesthetic harmonious restoration almost indistinguishable from surrounding natural teeth, and that, while having sufficient mechanical strength and radiopacity and good ease of polishing as a restorative material, desirably resists discoloration not only in the intraoral environment but under accelerated heating conditions and under xenon light, without losing fluorescence even under these conditions. The present invention also provides a cured product of such a dental curable composition. The present invention relates to a dental curable composition comprising a polymerizable monomer (A), an inorganic filler (B), a polymerization initiator (C), and a fluorescent agent (D), wherein the fluorescent agent (D) comprises a 9- to 11-membered benzo-fused heterocyclic compound containing two or more heteroatoms (excluding benzoimidazole compounds).
FILMOGENIC COMPOSITIONS FOR TOPICAL ANAESTHETIC BIOADHESIVES - TABS, FOR CONTROLLED RELEASE OF ACTIVE PRINCIPLES AND TOPICAL ANAESTHETIC BIOADHESIVES
Filmogenic compositions are described for topical anaesthetic bioadhesives (TABs) comprising a) a xanthan biopolymer matrix selected from Xanthomonas species and pathovars, including Xanthomonas campestris pathovars campestris and maninhotis, and Xanthomonas arboricola pathovar pruni, a producer of pruni xanthan, wherein the matrix is made of pure or combined xanthan varieties in any proportion, said matrix comprising between 1% and 95% by weight of the total weight of the composition, and additives or excipients; b) at least one anaesthetic, in a proportion of 0.1% to 50% by weight of the total weight of the composition. The topical anaesthetic bioadhesives (TABs) are also described, and they may be applied to the gingival mucosa and/or alveolar mucosa on the buccal (1) or lingual/buccal (2) surfaces with extensions and anatomical contours for crowns of the upper and lower dental arches.
Dental materials and method of manufacture
Dental materials may be made from polyhydric phenols that are non-genotoxic and exhibit estrogenic activity less than that of bisphenol S, while exhibiting properties such as strength and flexibility comparable to those of conventional BPA-derived dental materials.
Photo-cleavable primer compositions and methods of use
In one embodiment, the present application discloses a photo-cleavable surface binding compound of the Formula I and Formula II: ##STR00001##
wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound.
Photo-cleavable primer compositions and methods of use
In one embodiment, the present application discloses a photo-cleavable surface binding compound of the Formula I and Formula II: ##STR00001##
wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound.
SURFACE PRIMER COMPOSITIONS AND METHODS OF USE
In one embodiment, the present application discloses a surface binding compound of the Formula I or Formula II:
##STR00001##
wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound of the Formula I or Formula II.
Surface primer compositions and methods of use
In one embodiment, the present application discloses a surface binding compound of the Formula I or Formula II: ##STR00001##
wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound of the Formula I or Formula II.
Surface primer compositions and methods of use
In one embodiment, the present application discloses a surface binding compound of the Formula I or Formula II: ##STR00001##
wherein the variables EG, EG1, SP1, SP2, SP3, Ar and BG are as defined herein. In another embodiment, the application discloses a method for forming a coating on a surface of a substrate using the surface binding compound of the Formula I or Formula II.
Multi-functional micro and nanoparticles for use in root canal therapies
Chitosan nanoparticles are provided for use in the in vivo treatment of connective tissues in root canal therapies. The nanoparticles are optionally linked with one or more photoactivatable compounds for providing antibacterial/antibiofilm properties, neutralizing bacterial byproducts and/or chemical/photodynamic crosslinking to achieve enhanced mechanical properties, chemical stability in connective tissues and/or to improve surface/interfacial integrity between filling material and connective tissue.