A method of smoothing teeth by, for instance, filling in cracks, chips and eroded areas by applying calcium and/or casein and/or phosphate and a source of OH.sup.− ions thereto. The method optionally provides that very thin layer(s) of dental cement be interlaced with other applied materials, and that the results be maintained in contact with the teeth involved by application of a composition of matter that adheres to said teeth and holds the results in place, while allowing at least some permeation of saliva therethrough. The method can optionally involve application of a backing strip or tray or the like to secure the other materials in place, but this is not a requirement where the composition of matter is sufficiently securing.

The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and pro longed release of at least one pharmaceutically active agent at the bone loss site.

Disclosure is a tooth mineralization solution and a mineralization method thereof. The tooth mineralization solution can be used to mineralize collagen and teeth. The mineralization solution component of the present application comprises two parts, namely, reagent A containing non-collagenous protein analogue and calcium salt, and reagent B is phosphate solution. The mineralization method of the tooth mineralization solution of the present application comprises the steps of first applying the reagent A to the surface of tooth, and then applying the reagent B to achieve tooth mineralization. In addition, the mineralization solution of the present application can also be used to achieve biomimetic mineralization of collagen by the same method, comprising the steps of soaking or floating single-layer reconstituted collagen fibril, collagen gel or collagen sponge in the reagent A, and then soaking or floating in the reagent B to achieve biomimetic mineralization.

A dental curable composition which comprises a radically polymerizable monomer component (A), a polymerizing catalyst (B) and an inorganic granular material (C), characterized in that: the radically polymerizable monomer component (A) contains a bifunctional monomer (A-1) represented by the following formula (α),
R.sub.P—SP.sup.1—R.sub.P  (α) where, R.sub.P is a radically polymerizable group represented by CH.sub.2═C(R)—COO— or CH.sub.2═C(R)—CONH—, wherein R is a hydrogen atom or a hydrocarbon group having 1 to 3 carbon atoms, and SP.sup.1 is a hydrocarbon group having 5 to 15 carbon atoms, and the content of the bifunctional monomer (A-1) in the radically polymerizable monomer component (A) is 5 to 40% by mass under a condition that the content of a diluting monomer (A-2) represented by the following formula (β),
R.sub.P—SP.sup.2—R.sub.P  (β) where, R.sub.P is as defined in the above formula (α), and SP.sup.2 is an aliphatic hydrocarbon group different from SP.sup.1, an oxygen-containing aliphatic hydrocarbon group having not less than 2 oxygen atoms, or an oxygen-containing aromatic hydrocarbon group having not less than 3 oxygen atoms,
is zero or not more than 10% by mass.

Provided is a composite material which comprises a resin matrix and inorganic particles dispersed therein, wherein the inorganic particles comprise: one or more groups (G-PID) of spherical particles uniform in particle diameter which comprise aggregates of inorganic spherical particles having a specific average primary-particle diameter, have a narrow particle-size-distribution width, and have a lower refractive index than the resin matrix; and a group (G-SFP) of ultrafine particles. The inorganic spherical particles which constitute all the groups of spherical particles uniform in particle diameter contained in the resin matrix have an arrangement structure which is a short-range order structure satisfying a specific requirement. Also provided are a curable composition giving the composite material and a method for producing the curable composition.

Provided is a composite material which comprises a resin matrix and inorganic particles dispersed therein, wherein the inorganic particles comprise: one or more groups (G-PID) of spherical particles uniform in particle diameter which comprise aggregates of inorganic spherical particles having a specific average primary-particle diameter, have a narrow particle-size-distribution width, and have a lower refractive index than the resin matrix; and a group (G-SFP) of ultrafine particles. The inorganic spherical particles which constitute all the groups of spherical particles uniform in particle diameter contained in the resin matrix have an arrangement structure which is a short-range order structure satisfying a specific requirement. Also provided are a curable composition giving the composite material and a method for producing the curable composition.

The invention relates to a two-part dual cure dental composition with improved stability toward discoloration and premature polymerization. The dental composition comprises a Base Part and a Catalyst Part, the Base Part comprising polymerizable component(s) without an acidic moiety, optionally polymerizable component(s) with an acidic moiety, filler(s), transition metal component(s), peroxide component(s), stabilizer component(s) comprising a free-radical moiety, the Catalyst Part comprising polymerizable component(s) without an acidic moiety, filler(s), ascorbic acid component, photo-initiator system, stabilizer component(s) comprising a phosphite or sulfite moiety. The dental composition is in particular useful as bulk fill dental composite, dental resin cement, core build-up dental material or self- and dual cure dental adhesive. The invention further relates to an initiator system and the use of a stabilizer comprising a free-radical moiety.

The invention relates to a two-part dual cure dental composition with improved stability toward discoloration and premature polymerization. The dental composition comprises a Base Part and a Catalyst Part, the Base Part comprising polymerizable component(s) without an acidic moiety, optionally polymerizable component(s) with an acidic moiety, filler(s), transition metal component(s), peroxide component(s), stabilizer component(s) comprising a free-radical moiety, the Catalyst Part comprising polymerizable component(s) without an acidic moiety, filler(s), ascorbic acid component, photo-initiator system, stabilizer component(s) comprising a phosphite or sulfite moiety. The dental composition is in particular useful as bulk fill dental composite, dental resin cement, core build-up dental material or self- and dual cure dental adhesive. The invention further relates to an initiator system and the use of a stabilizer comprising a free-radical moiety.

The present invention relates in particular to the storage of dental material in a device (10, 10′) and the application of the dental material (20) from such a device (10,10′), and a method for treating dental material (20). In order to provide a solution that allows the simple and practical handling of a dental material (20) in the sense of storage, application and/or treatment thereof, inter alia, a device (10, 10′) for storage and application (20) comprising a cavity (12) for storage of the dental material (20) and a wall (14) surrounding the cavity (12) is proposed, wherein the wall (14) in at least a first temperature range is impermeable to radiation of at least a first wavelength or a first wavelength range in the range of 100 nm to 500 nm, wherein the wall (14) comprises at least one area that at least in a second temperature range is permeable to radiation of at least a second wavelength or a second wavelength range in the range of 600 nm to 50,000 nm.

The present invention relates in particular to the storage of dental material in a device (10, 10′) and the application of the dental material (20) from such a device (10,10′), and a method for treating dental material (20). In order to provide a solution that allows the simple and practical handling of a dental material (20) in the sense of storage, application and/or treatment thereof, inter alia, a device (10, 10′) for storage and application (20) comprising a cavity (12) for storage of the dental material (20) and a wall (14) surrounding the cavity (12) is proposed, wherein the wall (14) in at least a first temperature range is impermeable to radiation of at least a first wavelength or a first wavelength range in the range of 100 nm to 500 nm, wherein the wall (14) comprises at least one area that at least in a second temperature range is permeable to radiation of at least a second wavelength or a second wavelength range in the range of 600 nm to 50,000 nm.