A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

A biocompatible composite material for controlled release is disclosed, comprising a biocompatible metal oxide structure with a loaded network of pores. The pore network of the biocompatible composite material is filled with a uniformly distributed biologically active micellizing amphiphilic molecule, the size of these pores ranging from about 0.5 to about 100 nanometers. The material is characterized in that when exposed to phosphate-buffered saline (PBS), the controlled release of the active amphiphilic molecule is predominantly diffusion-driven over time.

Provided is a fluoroaluminosilicate glass powder that can provide a dental glass ionomer cement hardened body excellent in acid resistance, the glass powder including sodium and potassium which have an effect of lowering the reflective index of glass. A mass ratio of potassium to sodium in the component is in the range of from 1.2 to 1.9 in terms of oxide.

The present invention relates to oral care and dental implants. In particular, the present invention is a dental implant with a removable protective film that is used to prevent implant loss and remove unwanted residual cement.

Methods, devices and systems are disclosed for chemically bonding antibiotics to selected substrate materials which are not dissolved in normal physiological processes so that high local concentrations can be achieved during the inflammatory response. The antibiotics will remain permanently bonded to the substrate material until an infection occurs which releases the antibiotic in high concentrations to help control the infection. The high local concentrations may be much higher than systemic toxic levels, and can never reach toxic levels because the local dose is much less than needed to reach systemic toxicity if completely dissolved.

A bone cement formulation comprising: (a) magnetic calcium phosphate nanoparticles present in an amount of 5.0-95 wt. % and having a largest linear dimension of 150 nm to 50 microns; (b) polymerizable acrylate monomer present in an amount of 5.0-95 wt. %; and (c) polyacrylate polymer present in an amount of 0-80 wt. % and having a largest linear dimension from 5.0 to 500 microns. Upon exposure to an alternating magnetic field the formulation is heated which results in polymerization of the acrylate monomer component. The formulation may also be polymerized via the use of chain polymerization initiators.

A strontium-doped root canal filling paste, a preparation method therefor and use thereof in the treatment of dental pulp disease are provided. The strontium-doped root canal filling paste includes a component (a) and a component (b), wherein component (a) is selected from calcium silicate compounds, and component (b) is selected from strontium compounds. Component (a) accounts for 20%-40% of by weight of the paste, and component (b) accounts for 0.5%-10% by weight of the paste; and components (a) and (b) are doped in a physical doping manner.

The invention relates to a kit of parts for obtaining a glass ionomer composition, the kit of parts comprising Part P and Part L, Part P being a powder comprising acid-reactive glass, Part L being a liquid comprising water, the kit of parts containing in addition a polycarboxylic acid, the polycarboxylic acid being present in Part P or Part L or Part P and Part L, the polycarboxylic acid comprising a copolymer of acrylic acid and maleic acid, the acid-reactive glass being characterized by comprising P: 0-4 wt. %, F: 10-18 wt. %, O: 25-35 wt. %, Si: 10-16 wt. %, Al: 11-19 wt. %, Sr: 20-40 wt. %, La: 0-4 wt. % the combined amount of Al, Sr and F being >48 wt. %, wt. % with respect to the weight of the acid-reactive glass, and the ratio of Al and Si in the acid-reactive glass being greater than 1/1 with respect to weight. The invention also relates to the use of a particular acid reactive glass in combination with a particular polycarboxylic acid for improving the mechanical strength of a glass ionomer composition.

The invention relates to a kit of parts for obtaining a glass ionomer composition, the kit of parts comprising Part P and Part L, Part P being a powder comprising acid-reactive glass, Part L being a liquid comprising water, the kit of parts containing in addition a polycarboxylic acid, the polycarboxylic acid being present in Part P or Part L or Part P and Part L, the polycarboxylic acid comprising a copolymer of acrylic acid and maleic acid, the acid-reactive glass being characterized by comprising P: 0-4 wt. %, F: 10-18 wt. %, O: 25-35 wt. %, Si: 10-16 wt. %, Al: 11-19 wt. %, Sr: 20-40 wt. %, La: 0-4 wt. % the combined amount of Al, Sr and F being >48 wt. %, wt. % with respect to the weight of the acid-reactive glass, and the ratio of Al and Si in the acid-reactive glass being greater than 1/1 with respect to weight. The invention also relates to the use of a particular acid reactive glass in combination with a particular polycarboxylic acid for improving the mechanical strength of a glass ionomer composition.

To provide a carious tooth structure recovery agent that has convenience to treat multiple teeth at once, has aesthetics without discoloration of the treated area, and is capable of performing the preventive care for root surface caries and the initial caries treatment, and the carious tooth structure recovery agent contains a compound (a) having an acidic group represented by the following formula (I): R.sup.1X (I) (in which R.sup.1 represents an organic group having 40 or less carbon atoms that has or does not have at least one (meth)acryloyloxy group, and X represents an acidic group), a zinc ion (b1), water (c), and a hydrophilic solvent (d), and substantially does not contain a crosslinkable polymerizable monomer.