The present invention provides a dental material containing nanofibers and a biocompatible resin. In one embodiment, this dental material is an implant material, prosthetic material, or denture material and has mechanical strength suited to the site of use in the body as well as exceptional dimensional stability and exceptional wear resistance. Because the compressive strength can be controlled, excessive burden on the teeth when occlusal force is applied is suppressed when the dental material is used in the oral cavity. In addition, secondary caries can be suppressed because the antimicrobial properties make plaque less likely to adhere to the teeth and make the teeth less likely to be affected by bacteria. This dental material can be used without modification as a desired dental material, and can also be made into a desired dental material by molding as needed. In addition, materials produced from these nanofibers and this resin can also be used in applications other than dental materials.

Disclosed is a dental adhesive including a polymeric adhesive and a nanofiller dispersed in the polymeric adhesive, the nanofiller being constituted by graphene nanostructures which are properly dispersed inside the polymer adhesive and over the surface of the adhesive layer without formation of agglomerates, so that the dental adhesive exhibits significant antimicrobial and antibiofilm properties against pathogens of the oral cavity.

Provided herein are novel compositions for the restoration of demineralized tissues, such as dentin which has been demineralized by tooth decay. The remineralization agent comprises a bioactive ceramic component and a polyanionic macromolecular component, which may be admixed and applied to the target tissue and which will subsequently set to produce a remineralizing solid. The remineralizing solid will produce nanodroplets of mineral precursor solution, which such nanodroplets can infiltrate demineralized collagen matrices and which will form hydroxyapatite crystals therein by polymer-induced liquid precursor processes. The scope of the invention encompasses novel compositions and methods of treating demineralized tissues.

Provided herein are novel compositions for the restoration of demineralized tissues, such as dentin which has been demineralized by tooth decay. The remineralization agent comprises a bioactive ceramic component and a polyanionic macromolecular component, which may be admixed and applied to the target tissue and which will subsequently set to produce a remineralizing solid. The remineralizing solid will produce nanodroplets of mineral precursor solution, which such nanodroplets can infiltrate demineralized collagen matrices and which will form hydroxyapatite crystals therein by polymer-induced liquid precursor processes. The scope of the invention encompasses novel compositions and methods of treating demineralized tissues.

The present invention relates to providing a dental curable composition that, when cured, has high metal ion release ability and highly durable physical properties. The dental curable composition of the present invention includes: a sugar compound having an XM group, where X is an acid anion group and M is a metal cation; and a curable component.

The present invention relates to providing a dental curable composition that, when cured, has high metal ion release ability and highly durable physical properties. The dental curable composition of the present invention includes: a sugar compound having an XM group, where X is an acid anion group and M is a metal cation; and a curable component.

A three-dimensional printed dental device formed from rapid prototyping with printable polymerizable materials, the dental device comprising a polymeric composition, wherein the polymeric composition, after curing, has at least one property of flexural strength, flexural modulus, fracture toughness, and work of fracture that is at least 20% greater in measured value at 37 C. in comparison to measured value at 23 C.

A dental implant device in the form of an interface member for forming an individually customized dental implant abutment mounted on a connection platform of a dental implant anchor adapted to be implanted, the interface member is a hollow tubular member featuring an internal lumen defined between a non-customizable distal portion and a customizable proximal portion.

To provide a cured product having high fracture energy, provided are a curable composition, including: organic-inorganic composite particles; (a polymerizable monomer; a polymerization initiator; and inorganic particles, in which a cured body formed by curing the curable composition includes: a matrix formed by curing all constituent components of the curable composition except for the organic-inorganic composite particles; and the organic-inorganic composite particles dispersed and contained in the cured body, and in which an elastic modulus M of the matrix is larger than an elastic modulus P of the organic-inorganic composite particles by 3.0 GPa or more, a curable composition for dental use, and an organic-inorganic composite particle for dental use.

The present invention relates to: composition for differentiating non-dental mesenchymal stem cells into odontoblasts comprising CPNE7 protein or gene; method for differentiating in vitro non-dental mesenchymal stem cells using the same; and also use thereof.