A61K8/11

SPRAY-DRIED DYE COMPOSITIONS, PROCESS FOR THE PRODUCTION AND USE THEREOF

The invention relates to spray-dried, washfast dye compositions (preferably in the form of pigment powders) having a bleeding rate of ≤0.5% and consisting of water-soluble functional dyes, preferably food dyes, which are firmly incorporated in a silica matrix. Apart from low bleeding of dye, these compositions are remarkable for their high stability to pH changes and/or ascorbic acid. The invention is also directed to the production of the dye compositions and the use thereof. The dye compositions are preferably employed in coloring foods, cosmetics, pharmaceutical products, but also in other uses.

COMPOSITION FOR SKIN WHITENING, COMPRISING CARVONE OR SALT THEREOF AS ACTIVE INGREDIENT
20220370317 · 2022-11-24 · ·

A composition containing carvone or a salt thereof as an active ingredient is disclosed. A new use of the composition is also disclosed. The composition is effective in whitening skin of a subject, and capable of exhibiting an excellent melanogenesis inhibitory effect. The composition has an excellent effect of inhibiting melanogenesis induced by melanocyte-stimulating hormone (αMSH), is safe for the human body, and has no or minimum adverse effects. Thus, the composition may be variously used as a material for cosmetics, functional health foods, food ingredients or additives, dietary supplement, nutraceutical composition, pharmaceuticals, quasi-drugs, or the like.

COMPOSITION FOR SKIN WHITENING, COMPRISING CARVONE OR SALT THEREOF AS ACTIVE INGREDIENT
20220370317 · 2022-11-24 · ·

A composition containing carvone or a salt thereof as an active ingredient is disclosed. A new use of the composition is also disclosed. The composition is effective in whitening skin of a subject, and capable of exhibiting an excellent melanogenesis inhibitory effect. The composition has an excellent effect of inhibiting melanogenesis induced by melanocyte-stimulating hormone (αMSH), is safe for the human body, and has no or minimum adverse effects. Thus, the composition may be variously used as a material for cosmetics, functional health foods, food ingredients or additives, dietary supplement, nutraceutical composition, pharmaceuticals, quasi-drugs, or the like.

Polymeric composite particles

Compositions are provided that include a matrix and a polymeric composite particles disposed in the matrix. The polymeric composite particles include a porous polymeric core and a fragrance positioned within the porous polymeric core. Polymeric composite particles are also provided including a porous polymeric core, a fragrance positioned within the porous polymeric core, and a coating layer around the porous polymeric core. Further, a method of determining a minimum temperature of a composition is provided including providing a composition including polymeric composite particles disposed in a matrix, heating the composition, releasing at least a portion of the fragrance as a vapor from the porous polymeric core of the polymeric composite particles at or above the minimum temperature, and detecting at least a portion of the fragrance vapor in a location outside of the matrix.

Polymeric composite particles

Compositions are provided that include a matrix and a polymeric composite particles disposed in the matrix. The polymeric composite particles include a porous polymeric core and a fragrance positioned within the porous polymeric core. Polymeric composite particles are also provided including a porous polymeric core, a fragrance positioned within the porous polymeric core, and a coating layer around the porous polymeric core. Further, a method of determining a minimum temperature of a composition is provided including providing a composition including polymeric composite particles disposed in a matrix, heating the composition, releasing at least a portion of the fragrance as a vapor from the porous polymeric core of the polymeric composite particles at or above the minimum temperature, and detecting at least a portion of the fragrance vapor in a location outside of the matrix.

Microcapsules for controlled delivery of an active pharmaceutical ingredient
11590084 · 2023-02-28 ·

The present invention relates a microcapsule that comprises an active pharmaceutical ingredient and a polymeric shell comprised of polymeric materials such as polyether, polyester, polyamine, polyamide, polyurea, polyurethane, polythiocarbamate, and polythiocarbonate. The outer surface of shell comprises surface functional groups such as hydroxide, primary amine, carboxylic acid, or protected forms thereof. These surface functional groups may be reacted further with reactants to place specific organic groups on the surface of the microcapsule. Such microcapsules are prepared by a modified interfacial condensation polymerization.

Microcapsules for controlled delivery of an active pharmaceutical ingredient
11590084 · 2023-02-28 ·

The present invention relates a microcapsule that comprises an active pharmaceutical ingredient and a polymeric shell comprised of polymeric materials such as polyether, polyester, polyamine, polyamide, polyurea, polyurethane, polythiocarbamate, and polythiocarbonate. The outer surface of shell comprises surface functional groups such as hydroxide, primary amine, carboxylic acid, or protected forms thereof. These surface functional groups may be reacted further with reactants to place specific organic groups on the surface of the microcapsule. Such microcapsules are prepared by a modified interfacial condensation polymerization.

Micelles and vesicles for the delivery of glycopeptides

Methods for quality control and optimizing the formation and characterization of micelles, vesicles or other aggregates are described herein. Pharmaceutically relevant peptides may be modified to form glycopeptide surfactants which form micelles or other aggregates with another surfactant. Glycopeptide and glycolipid surfactants can aggregate to form particles that enhance drug delivery. The glycopeptide surfactants may be drugs or pro-drugs which are delivered via the micelles or other aggregated structures.

MICROCAPSULES AND COSMETIC COMPOSITIONS COMPRISING THE SAME
20230054620 · 2023-02-23 ·

Disclosed is a microcapsule comprising: (i) a core comprising a benefit agent; and (ii) a shell comprising silica; wherein said shell comprises plate-like inorganic materials having an average thickness of 1-1000 nm; wherein said benefit agent is fragrance, pro-fragrance, hair conditioning agent, anti-dandruff agent, moisturizers, emollients, dyes and/or pigments, colour care additives (including dye fixing agents), or a mixture thereof.

MICROCAPSULES AND COSMETIC COMPOSITIONS COMPRISING THE SAME
20230054620 · 2023-02-23 ·

Disclosed is a microcapsule comprising: (i) a core comprising a benefit agent; and (ii) a shell comprising silica; wherein said shell comprises plate-like inorganic materials having an average thickness of 1-1000 nm; wherein said benefit agent is fragrance, pro-fragrance, hair conditioning agent, anti-dandruff agent, moisturizers, emollients, dyes and/or pigments, colour care additives (including dye fixing agents), or a mixture thereof.