Method for remineralizing teeth or increasing hardness of tooth enamel by application of Brazilian green propolis oil or its components.

Method for remineralizing teeth or increasing hardness of tooth enamel by application of Brazilian green propolis oil or its components.

The present invention relates to hydrogel particles coated with lipid, which are made from dispersing hydrogel particles in an organic solvent in which lipids are dissolved, and to a method for manufacturing same. Unlike the existing method for manufacturing hydrogel core vesicles, the present invention can effectively manufacture same by using an emulsification method, without involving the steps of chemical treatment of the surface of hydrogels or dilution, thereby facilitating mass production and preventing the decrease of drug encapsulation efficiency. The present method could be widely used for research on delivery carriers of oil/water-soluble active material or cell structure reproduction and more particularly, a keratinocyte mimetic of the present invention containing natural moisturizing factors can contain a large quantity of bound water for a long time, thereby exhibiting superior capability to retain moisture and moisturize, and providing a composition for an ingredient in cosmetics for moisturizing.

The present invention relates to hydrogel particles coated with lipid, which are made from dispersing hydrogel particles in an organic solvent in which lipids are dissolved, and to a method for manufacturing same. Unlike the existing method for manufacturing hydrogel core vesicles, the present invention can effectively manufacture same by using an emulsification method, without involving the steps of chemical treatment of the surface of hydrogels or dilution, thereby facilitating mass production and preventing the decrease of drug encapsulation efficiency. The present method could be widely used for research on delivery carriers of oil/water-soluble active material or cell structure reproduction and more particularly, a keratinocyte mimetic of the present invention containing natural moisturizing factors can contain a large quantity of bound water for a long time, thereby exhibiting superior capability to retain moisture and moisturize, and providing a composition for an ingredient in cosmetics for moisturizing.

An application of a transgenic stem cell-derived exosome in preparing a medicament or whitening cosmetic is provided. In the present disclosure, miR-27b-3p is transfected into an epidermal stem cell, and a transgenic stem cell-derived exosome is harvested. It is experimentally verified that the exosome can inhibit the expression of PIK3R3 protein in melanocytes and the proliferation and migration of melanocytes; and safety experiments further demonstrate the safety of the exosome. Therefore, corresponding medicaments or cosmetics prepared from the exosome have excellent medicinal and cosmetic application prospects.

An application of a transgenic stem cell-derived exosome in preparing a medicament or whitening cosmetic is provided. In the present disclosure, miR-27b-3p is transfected into an epidermal stem cell, and a transgenic stem cell-derived exosome is harvested. It is experimentally verified that the exosome can inhibit the expression of PIK3R3 protein in melanocytes and the proliferation and migration of melanocytes; and safety experiments further demonstrate the safety of the exosome. Therefore, corresponding medicaments or cosmetics prepared from the exosome have excellent medicinal and cosmetic application prospects.

Disclosed herein are compositions and methods for improving pigmentation. Compositions as described herein comprise one or more peptides.

Disclosed herein are compositions and methods for improving pigmentation. Compositions as described herein comprise one or more peptides.

The present disclosure provides a liposomal topical formulation comprising dutasteride having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.

The present disclosure provides a liposomal topical formulation comprising dutasteride having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.