Provided are microvesicles isolated from milk, compositions thereof and uses for the preparation of milk formulas. Further provided are microvesicles, including exosomes and/or fat globules which encapsulate various miRNA molecules and uses thereof, as exemplified by supplementing milk formulas.

A dairy spread composition is suggested, obtained or obtainable by: (a) providing a cream fraction having a content of at least 40% by weight fat and at least 6% by weight fat-free dry matter; (b) subjecting the cream fraction to a temperature ripening step; (c) churning the ripened cream fraction, and separating the buttermilk; (d) adding salt and an acidification permeate to the butter such obtained; (e) mixing the acidified at 12 to 16 C. with a vegetable fat that is liquid at this temperature; (f) adding an aqueous phase to the blend in small doses, and (g) packaging the blend after homogenisation and cooling.

The invention relates to a method of preparing a whey-derived composition enriched with respect to whey phospholipids by membrane filtration, and preferably also enriched with respect to other membrane components from whey. The membrane filtration is furthermore followed by a special microfiltration-based germ filtration which the inventors have found to be efficient for reducing the microbial content of the whey-derived composition while keeping nutritionally important components in the whey-derived composition. The invention furthermore relates to the whey-derived composition as such, use of the whey-derived composition as in ingredient in nutritional products, and to nutritional products comprising the whey-derived composition.

A milk ingredient is enriched in polar lipids, in particular in phospholipids and in sphingolipids, in which the percentage of phospholipids is greater than 10% by weight, relative to the weight of solids of the ingredient, and a method obtains the same starting from pasteurized cream and is used in food and/or pharmaceutical products.