A composition includes at least one polymer doped with graphene oxide to induce conductivity in the polymer and at least one agent immobilized at least one of (i) on graphene oxide extending from the surface of the composite material or (ii) within the composite material.

Printed delivery devices are disclosed herein. In some embodiments, a printed delivery device (100) includes a support substrate. A first printed composition (102), including a first supplement, is coated onto the support substrate (202) and a second printed composition (102) disposed on the first printed composition. A decorative film is applied to one or more of the first printed composition, second printed composition, or the support substrate (602).

The invention is directed to a biodegradable, phase separated, thermoplastic multi-block copolymer, to a process for preparing a biodegradable, phase separated, thermoplastic multi-block copolymer, to the use of a biodegradable, semi-crystalline, phase separated, thermoplastic multi-block copolymer, and to a composition for the delivery of at least one biologically active compound to a host.

The biodegradable, phase separated, thermoplastic multi-block copolymer of the invention comprises at least one amorphous hydrolysable pre-polymer (A) segment and at least one semi-crystalline hydrolysable pre-polymer (B) segment, wherein said multi-block copolymer under physiological conditions has a T.sub.g of 37° C. or less and a T.sub.m of 50-110° C.; the segments are linked by a multifunctional chain extender; the segments are randomly distributed over the polymer chain; and the pre-polymer (B) segment comprises a X-Y-X tri-block, wherein Y is a polymerisation initiator, and X is a poly(p-dioxanone) segment with a block length expressed in p-dioxanone monomer units of 7 or more.

Disclosed is a description and methods for formulating oral films containing lipophilic active ingredient(s), more particularly lipophilic active having a positive log P. The method involves dispersing the lipophilic active(s) in a carrier oil and uniformly distributing them as emulsified oil droplets into a polymer matrix. The methods reported here produce oral films containing a stable emulsion with up to 40% oil phase. The oil phase consists of the carrier oil and lipophilic active(s). This offers the possibility to enhance the amount of lipophilic actives to be included in the film formulation while preserving the film characteristics. The resulting oral films offer a standardized dosage form for lipophilic actives as well as easier and more convenient administration, transportation, handling, and storage.

The present invention relates to the use of Afabicin in a method of treating bacterial infections involving biofilm that contains Staphylococcus bacteria, wherein the method comprises administering Afabicin in combination with at least one further agent selected from lipopeptides, glycopeptides and lincosamides, such as Daptomycin and/or Vancomycin to the patient.

The present invention relates to a method and to a device for producing solid, at least semisolid dosage forms of pharmaceutical active agents, nutraceutical active agents and/or dietary supplemental active agents, wherein the dosage form is generated in an additive fashion by depositing a building substance in the form of dots.

A method of administering diazepam having a food effect is described.

The present invention provides devices and methods for delivering a population of cells or a therapeutic agent to a subject in need thereof.

Soluble drug delivery films can exhibit an enhanced stability.

A gas permeable layer capable of supplying hydrogen includes a thin layer, encapsulating a hydrogen production formula. An outer side of the thin layer is airtight. An inner side is air-permeable. An inner side surface has a plurality of small holes. The thin layer can be a single layer or a composite layer. The hydrogen production formula does not dissipate. The hydrogen production formula absorbs moisture in the air or liquid water, thereby generating hydrogen. The hydrogen is released onto the skin and into the human body through the small holes. The hydrogen production formula includes metal peroxides, metal hydroxides, or metal hydrides and aluminum powder, or microsilica. The gas permeable layer can be used in sanitary products including eye masks, mouth masks, face masks, cosmetic facial masks, bras, pasties, nursing pads, sanitary napkins (towels), diapers, panty liners, wound dressing, woundplasts, bandage gauze, decubitus pads.