A61K31/035

TREATMENT OF 22Q11.2 DELETION SYNDROME WITH CANNABIDIOL

The present technology relates to methods of treating one or more behavioral symptoms (for example, anxiety) of 22q11.2 deletion syndrome in a subject by administering, e.g., transdermally, an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of 22q11.2 deletion syndrome are treated in the subject

METHODS FOR TREATING DISEASES

Some embodiments of the invention include methods of using a compound such as Formula (I), Formula (II), or I-1 (e.g., in compositions or in pharmaceutical compositions) for treating diseases (e.g., cancer such as chemo-resistant cancer or cancer-therapy-resistant cancer). Additional embodiments of the invention are also discussed herein.

METHODS FOR TREATING DISEASES

Some embodiments of the invention include methods of using a compound such as Formula (I), Formula (II), or I-1 (e.g., in compositions or in pharmaceutical compositions) for treating diseases (e.g., cancer such as chemo-resistant cancer or cancer-therapy-resistant cancer). Additional embodiments of the invention are also discussed herein.

Determination of personalized endocannabinoid genotypes and associated recommendations
11896576 · 2024-02-13 · ·

An example embodiment may involve (i) receiving, by a server device, deoxyribonucleic acid (DNA) information associated with a user; (ii) parsing, by the server device, the DNA information to identify one or more single nucleotide polymorphisms (SNPs); (iii) determining, by the server device and based on the identified SNPs, an endocannabinoid genotype of the user; (iv) determining, based on the endocannabinoid genotype of the user, a recommendation of one or more cannabinoid formulations; (v) transmitting, to a client device associated with the user, a web-based representation of a first graphical user interface; and (vi) receiving, from the client device, an indication to display a detailed representation of a particular cannabinoid formulation of the one or more cannabinoid formulations.

Determination of personalized endocannabinoid genotypes and associated recommendations
11896576 · 2024-02-13 · ·

An example embodiment may involve (i) receiving, by a server device, deoxyribonucleic acid (DNA) information associated with a user; (ii) parsing, by the server device, the DNA information to identify one or more single nucleotide polymorphisms (SNPs); (iii) determining, by the server device and based on the identified SNPs, an endocannabinoid genotype of the user; (iv) determining, based on the endocannabinoid genotype of the user, a recommendation of one or more cannabinoid formulations; (v) transmitting, to a client device associated with the user, a web-based representation of a first graphical user interface; and (vi) receiving, from the client device, an indication to display a detailed representation of a particular cannabinoid formulation of the one or more cannabinoid formulations.

ACTIVE AGENTS AGAINST PROTOZOA
20190358174 · 2019-11-28 ·

The invention relates to compounds, which are directed against protozoa, for use in the treatment of protozoal infections. The compounds are characterized in that they inhibit the formate-nitrite transporter of protozoa.

ACTIVE AGENTS AGAINST PROTOZOA
20190358174 · 2019-11-28 ·

The invention relates to compounds, which are directed against protozoa, for use in the treatment of protozoal infections. The compounds are characterized in that they inhibit the formate-nitrite transporter of protozoa.

Substituted Stilbenes as Inhibitors of NF-kappaB and Activators of Nrf2
20190160021 · 2019-05-30 ·

The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and makes them particularly useful in the treatment of inflammation, including chronic inflammation and a number of related chronic disease states and conditions, including neurological diseases, including Alzheimer's, Alzheimer's prodrome and mild cognitive impairment, and other diseases and conditions, such as Parkinson's disease, depression, bipolar disorders and autism spectrum disorders. Compounds, pharmaceutical compositions and methods of treatment are described.

Substituted Stilbenes as Inhibitors of NF-kappaB and Activators of Nrf2
20190160021 · 2019-05-30 ·

The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and makes them particularly useful in the treatment of inflammation, including chronic inflammation and a number of related chronic disease states and conditions, including neurological diseases, including Alzheimer's, Alzheimer's prodrome and mild cognitive impairment, and other diseases and conditions, such as Parkinson's disease, depression, bipolar disorders and autism spectrum disorders. Compounds, pharmaceutical compositions and methods of treatment are described.

Substituted Stilbenes as Inhibitors of NF-kappaB and Activators of Nrf2
20190160021 · 2019-05-30 ·

The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and makes them particularly useful in the treatment of inflammation, including chronic inflammation and a number of related chronic disease states and conditions, including neurological diseases, including Alzheimer's, Alzheimer's prodrome and mild cognitive impairment, and other diseases and conditions, such as Parkinson's disease, depression, bipolar disorders and autism spectrum disorders. Compounds, pharmaceutical compositions and methods of treatment are described.