The invention is directed to a composition that safely removes a cured dental cement or resin from metal brackets, metal braces, and enamel surfaces of teeth. It contains eugenol, isoeugenol, methyl-eugenol or an isomer thereof. A method for removing orthodontic fixtures adhered with a dental cement or resin to the enamel surfaces of teeth from these surfaces by contacting the dental cement or resin with a composition containing eugenol.

Pharmaceutical compositions having enhanced active component permeation properties are described.

Pharmaceutical compositions having enhanced active component permeation properties are described.

Disclosed herein are compounds, compositions and methods of their use to treat HIV/AIDS disease in a subject in need thereof, wherein the compositions comprise small molecule inhibitors that inhibit viral preparation or viral recruitment of human tRNA3Lys.

Disclosed herein are compounds, compositions and methods of their use to treat HIV/AIDS disease in a subject in need thereof, wherein the compositions comprise small molecule inhibitors that inhibit viral preparation or viral recruitment of human tRNA3Lys.

Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (II): ##STR00001## including stereoisomers and pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2a, R.sup.2b, R.sup.2c, R.sup.3, R.sup.4, R.sup.5, R.sup.6a, R.sup.6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (II): ##STR00001## including stereoisomers and pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2a, R.sup.2b, R.sup.2c, R.sup.3, R.sup.4, R.sup.5, R.sup.6a, R.sup.6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

The invention relates in general to a medicament comprising Metformin or a salt thereof; and a compound having the general formula (I) or a salt thereof. The invention further relates to a pharmaceutical composition comprising the medicament for use in the prevention or treatment of a metabolic disease or a cardiovascular disease.

The invention relates in general to a medicament comprising Metformin or a salt thereof; and a compound having the general formula (I) or a salt thereof. The invention further relates to a pharmaceutical composition comprising the medicament for use in the prevention or treatment of a metabolic disease or a cardiovascular disease.

The invention relates in general to a medicament comprising Metformin or a salt thereof; and a compound having the general formula (I) or a salt thereof. The invention further relates to a pharmaceutical composition comprising the medicament for use in the prevention or treatment of a metabolic disease or a cardiovascular disease.