A61K31/115

Antimicrobial formulations for the improved treatment of veterinary hoof infections
11344508 · 2022-05-31 · ·

There is provided a composition comprising an organic material and at least a first surfactant which following addition of an aqueous solution to the composition can form a biphasic system, wherein the biphasic system is useful for the treatment of or prevention of hoof infections. Also provided is a biphasic system useful for the treatment of or prevention of hoof infections, wherein the biphasic system comprises the composition and an aqueous phase wherein the composition is dispersed as droplets within the aqueous phase.

COMPOSITIONS CONTAINING FORMALDEHYDE AND ORGANIC ACID FOR PREVENTION OF AFRICAN SWINE FEVER
20220000803 · 2022-01-06 ·

The present invention relates to compositions and methods to prevent the incidence of African Swine Fever (ASF) in swine. Another aspect of the present invention relates to the administration of formaldehyde and at least one organic acid, preferably in the animal's feed or drinking water. The invention is unexpectedly effective in controlling the spread of the ASP virus but also keeping the animal feed virus-free for up to 7 days.

COMPOSITIONS CONTAINING FORMALDEHYDE AND ORGANIC ACID FOR PREVENTION OF AFRICAN SWINE FEVER
20220000803 · 2022-01-06 ·

The present invention relates to compositions and methods to prevent the incidence of African Swine Fever (ASF) in swine. Another aspect of the present invention relates to the administration of formaldehyde and at least one organic acid, preferably in the animal's feed or drinking water. The invention is unexpectedly effective in controlling the spread of the ASP virus but also keeping the animal feed virus-free for up to 7 days.

COMPOSITIONS CONTAINING FORMALDEHYDE AND ORGANIC ACID FOR PREVENTION OF AFRICAN SWINE FEVER
20220000803 · 2022-01-06 ·

The present invention relates to compositions and methods to prevent the incidence of African Swine Fever (ASF) in swine. Another aspect of the present invention relates to the administration of formaldehyde and at least one organic acid, preferably in the animal's feed or drinking water. The invention is unexpectedly effective in controlling the spread of the ASP virus but also keeping the animal feed virus-free for up to 7 days.

ANTIMICROBIAL FORMULATIONS FOR THE TREATMENT OF VETERINARY HOOF INFECTIONS
20220257530 · 2022-08-18 ·

There is provided a composition comprising an organic material and at least a first surfactant which following addition of an aqueous solution to the composition can form a biphasic system, wherein the biphasic system is useful for the treatment of or prevention of hoof infections. Also provided is a biphasic system useful for the treatment of or prevention of hoof infections, wherein the biphasic system comprises the composition and an aqueous phase wherein the composition is dispersed as droplets within the aqueous phase.

ANTIMICROBIAL FORMULATIONS FOR THE TREATMENT OF VETERINARY HOOF INFECTIONS
20220257530 · 2022-08-18 ·

There is provided a composition comprising an organic material and at least a first surfactant which following addition of an aqueous solution to the composition can form a biphasic system, wherein the biphasic system is useful for the treatment of or prevention of hoof infections. Also provided is a biphasic system useful for the treatment of or prevention of hoof infections, wherein the biphasic system comprises the composition and an aqueous phase wherein the composition is dispersed as droplets within the aqueous phase.

Pharmaceutical composition for preventing and treating pancreatic cancer, containing gossypol and phenformin as active ingredients

The present disclosure relates to a pharmaceutical composition comprising a combination of anticancer agents, capable of creating a synergistic effect when co-administer in the treatment of cancer, and more specifically, the present invention suggests anticancer agents capable of creating a synergistic effect when co-administered with gossypol and phenformin. The anticancer agents selected as said anticancer agents in the present disclosure are sorafenib, vemurafenib, irinotecan, cisplatin, paclitaxel, and doxorubicin, and each of the aforementioned anticancer agent, when co-administered as a triple-drug combination with gossypol and phenformin can provide a significant synergistic effect in terms of the effect of suppressing the proliferation of cancer and killing cancer cell, compared to each mono-drug treatment group and a dual-drug treatment group of gossypol+phenformin.

Pharmaceutical composition for preventing and treating pancreatic cancer, containing gossypol and phenformin as active ingredients

The present disclosure relates to a pharmaceutical composition comprising a combination of anticancer agents, capable of creating a synergistic effect when co-administer in the treatment of cancer, and more specifically, the present invention suggests anticancer agents capable of creating a synergistic effect when co-administered with gossypol and phenformin. The anticancer agents selected as said anticancer agents in the present disclosure are sorafenib, vemurafenib, irinotecan, cisplatin, paclitaxel, and doxorubicin, and each of the aforementioned anticancer agent, when co-administered as a triple-drug combination with gossypol and phenformin can provide a significant synergistic effect in terms of the effect of suppressing the proliferation of cancer and killing cancer cell, compared to each mono-drug treatment group and a dual-drug treatment group of gossypol+phenformin.

Messenger RNA therapy for treatment of articular disease
10864267 · 2020-12-15 · ·

The present invention provides, among other things, a method of intra-articular delivery of messenger RNA (mRNA), comprising administering into a joint of a subject in need of delivery a composition comprising an mRNA encoding a protein, such that the administering of the composition results in expression of the protein encoded by the mRNA in the joint.

Bupropion as a modulator of drug activity
10772850 · 2020-09-15 · ·

Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.