A61K31/132

TAUROLIDINE TREATMENT FOR MYC-EXPRESSING TUMORS IN MAMMALIAN BODIES
20220323451 · 2022-10-13 ·

A method for treating a cancer which overexpresses any of N-myc genes, C-myc genes and/or L-myc genes in a mammalian body, the method comprising:

administering a composition to the mammalian body, wherein the composition comprises at least one from the group consisting of taurolidine; taurultam; taurinamide; methylene glycol; taurultam and taurinamide in a ratio of 1 taurultam:7 taurinamide; and taurultam, taurinamide and methylene glycol in a ratio of 1 taurultam:7 taurinamide:1 methylene glycol.

TAUROLIDINE TREATMENT FOR MYC-EXPRESSING TUMORS IN MAMMALIAN BODIES
20220323451 · 2022-10-13 ·

A method for treating a cancer which overexpresses any of N-myc genes, C-myc genes and/or L-myc genes in a mammalian body, the method comprising:

administering a composition to the mammalian body, wherein the composition comprises at least one from the group consisting of taurolidine; taurultam; taurinamide; methylene glycol; taurultam and taurinamide in a ratio of 1 taurultam:7 taurinamide; and taurultam, taurinamide and methylene glycol in a ratio of 1 taurultam:7 taurinamide:1 methylene glycol.

TAUROLIDINE TREATMENT FOR MYC-EXPRESSING TUMORS IN MAMMALIAN BODIES
20220323451 · 2022-10-13 ·

A method for treating a cancer which overexpresses any of N-myc genes, C-myc genes and/or L-myc genes in a mammalian body, the method comprising:

administering a composition to the mammalian body, wherein the composition comprises at least one from the group consisting of taurolidine; taurultam; taurinamide; methylene glycol; taurultam and taurinamide in a ratio of 1 taurultam:7 taurinamide; and taurultam, taurinamide and methylene glycol in a ratio of 1 taurultam:7 taurinamide:1 methylene glycol.

Nail hardening composition and method of use
11628148 · 2023-04-18 ·

A composition and method for treatment of brittle, broken, cracked or otherwise damaged nail and hoof plates. The composition is an aqueous-organic medium containing a non-covalent complex of a diamine and an organic acid or an aqueous-organic medium with a diamine alone.

Nail hardening composition and method of use
11628148 · 2023-04-18 ·

A composition and method for treatment of brittle, broken, cracked or otherwise damaged nail and hoof plates. The composition is an aqueous-organic medium containing a non-covalent complex of a diamine and an organic acid or an aqueous-organic medium with a diamine alone.

PROBIOTICS, METABOLITES, AND USES THEREOF
20230158084 · 2023-05-25 ·

Some embodiments herein relate generally to compositions comprising microbial organisms and/or metabolites for improving the behavior of a subject, such as a subject having autism spectrum disorder (ASD), and methods of using the same. Some embodiments herein relate generally to profiles of gut bacteria and/or metabolites useful for determining a risk, presence, and/or severity of ASD.

PROBIOTICS, METABOLITES, AND USES THEREOF
20230158084 · 2023-05-25 ·

Some embodiments herein relate generally to compositions comprising microbial organisms and/or metabolites for improving the behavior of a subject, such as a subject having autism spectrum disorder (ASD), and methods of using the same. Some embodiments herein relate generally to profiles of gut bacteria and/or metabolites useful for determining a risk, presence, and/or severity of ASD.

USE OF COMPOUNDS THAT ARE ABLE TO CROSS-LINK THE EXTRACELLULAR MATRIX FOR PREVENTING OR INHIBITING THE MIGRATION OF CANCER CELLS
20230116113 · 2023-04-13 ·

The present invention relates to the field of cancer progression. The invention provides in vivo methods for preventing or inhibiting the migration of cancer cells away from the site of a tumour or a resected tumour, thus inhibiting invasion and metastasis, by contacting all or part of the tumour or resected tumour, or all or part of the vicinity of the tumour, with an agent which impedes the migration and/or proliferation of cancer cells, such as a cross-linking agent.

USE OF COMPOUNDS THAT ARE ABLE TO CROSS-LINK THE EXTRACELLULAR MATRIX FOR PREVENTING OR INHIBITING THE MIGRATION OF CANCER CELLS
20230116113 · 2023-04-13 ·

The present invention relates to the field of cancer progression. The invention provides in vivo methods for preventing or inhibiting the migration of cancer cells away from the site of a tumour or a resected tumour, thus inhibiting invasion and metastasis, by contacting all or part of the tumour or resected tumour, or all or part of the vicinity of the tumour, with an agent which impedes the migration and/or proliferation of cancer cells, such as a cross-linking agent.

COMPOSITIONS AND METHODS FOR PROMOTING CELLULAR METABOLIC FITNESS
20230115416 · 2023-04-13 ·

Provided are methods and compositions for promoting cellular metabolism and cellular repair in a tissue of a subject in need thereof. The composition includes at least one N-methyl-D-aspartate receptor (NMDAR) modulator to modulate metabolic activity in cells and at least one nuclear factor erythroid 2-related factor 2 (NRF2) modulator to modulate repair activity in cells. Optionally, the composition also includes at least one inactive component and at last one microbial modulator. The composition synergistically modulates a positive-feedback signal-amplification cycle comprising NMDAR and NRF2 in cells, which, in turn, promotes cellular metabolic fitness (CMF) in a tissue of a subject in need thereof.