Provided are: a filter medium with high dust collection efficiency, low pressure loss, and a long lifespan; and a filter material used for the filter medium. This composite structure includes ultrafine fibers having a fiber diameter of less than 500 nm, and beads. The outermost surface of the composite structure has at least 500/mm.sup.2 of beads with a diameter of 5 μm or more. The ultrafine fibers and the beads preferably have the same component.

A method for producing a film of the present invention includes the step of electrostatically spraying a liquid composition directly on the surface of skin using an electrostatic spray device to form a film on the skin. The electrostatic spray device includes a container capable of storing the liquid composition, a nozzle configured to eject the liquid composition, a power supply configured to apply a voltage to the nozzle, and a voltage stabilizer configured to stabilize the voltage applied by the power supply to the nozzle. The liquid composition contains component (a): one or more volatile substances selected from alcohols and ketones, and component (b): a polymer having film formability.

Described herein are polysulfone-based and polyether sulfone-based thin-film nanocomposite (TFNC) membranes produced by solution blow spinning (SBS) technology for forward osmosis applications, including desalination and wastewater treatment. These TFNC membranes exhibit ultra-fast water flux, low reverse salt flux, and fouling resistance.

A method of applying fibrous material to a medical device component involves coupling a medical device component a holder device, rotating a reservoir device containing a liquid polymeric solution to expel at least a portion of the liquid polymeric solution from an orifice of the reservoir device, the expelled at least a portion of the liquid polymeric solution forming one or more strands of fibrous material in a deposition plane, and rotating the holder device at least partially within the deposition plane to apply at least a first portion of the one or more strands of fibrous material to one or more surfaces of the medical device component, thereby forming a fibrous covering on the one or more surfaces of the medical device component.

An applicator is disclosed for applying a treatment solution to a treatment site of a patient. The applicator can include an applicator housing comprising a treatment solution reservoir. A cartridge can be removably disposed in the housing. The cartridge when arranged in the housing can be in fluid communication with the treatment solution reservoir. The cartridge can include an electrostatic module for electrostatically charging the treatment solution in the treatment solution reservoir; and a nozzle for applying the treatment solution.

A fiber-wrapped smokeless tobacco product includes smokeless tobacco and a plurality of polymeric fibers surrounding the smokeless tobacco. The polymeric fibers can have a basis weight of 5 gsm or less and a diameter of less than 100 microns. In some cases, the polymeric fibers are melt-blown polymeric fibers. In some cases, the polymeric fibers are centrifugal force spun polymeric fibers. A method of preparing a fiber-wrapped smokeless tobacco product includes melt-blowing or centrifugal force spinning a plurality of polymeric fibers to create an polymer deposition zone and passing a body comprising smokeless tobacco through the polymer deposition zone. In some cases, an electrostatic charge can be applied to the plurality of polymeric fibers, the body, or a combination thereof. In some cases, a spin is applied to the body when passing through the polymer deposition zone.

The present disclosure relates to compositions, devices, and methods for delivery of protein therapeutics, e.g., intravitreal delivery of a protein therapeutic to the eye. In particular, the present disclosure describes drug-delivery devices for injection into the eye of a subject in need thereof comprising a capsule having a bi-layered wall and a therapeutic agent, wherein the therapeutic agent is initially present within a luminal space of the capsule. Methods of making and using these drug-delivery devices are also described.

A method of making a solution including poly(ethylene terephthalate). The method includes dissolving poly(ethylene terephthalate) in a solvent mixture to form a solution, the solvent mixture including two solvent components. A Hansen Solubility Parameter Distance between the solvent mixture and HSP coordinates having a dispersion HSP of 18.02 MPa.sup.0.5, a polar HSP of 5.56 MPa.sup.0.5, and a hydrogen bonding HSP of 14.27 MPa.sup.0.5 is less than about 2 MPa.sup.0.5.

A medical implant is provided defined as an electrospun hollow-cored porous suture ring. The suture ring is a continuous ring made by rolling up circular sheet of electrospun material, which was electrospun over a cylindrical target. The suture ring, upon implantation, is capable of being absorbed and replaced by natural tissue due to ingrowth of cells and nutrients into pores of the electrospun hollow-cored biodegradable suture ring. The suture ring addresses at least some of the existing problems with suture or sewing rings.

The system for nano-coating a substrate (10) includes a housing (12) having an upper, dispensing chamber (18) in which electrospraying or electrospinning can occur, a lower storage chamber, and a wall (16) that separates the dispensing chamber (18) from the storage chamber. The dispensing chamber (18) includes first and second panels (24a), (24b) and a moveable collector (20) between the first and second panels (24a), (24b). Solution dispensing nozzles (26) are disposed in apertures (45) in the panels (24a), (24b), and extend from a front surface of each panel (24a), (24b). A plurality of solution supply tubes (54) extend from a rear surface of each panel (24a), (24b) to a pump (34) in the lower housing. Inner panel channels (52) are defined within each panel (24a), (24b) between the tubes (54) and the nozzles (26).