Methods for treating an ear condition in a subject, comprising topically administering to the ear of the subject in need thereof a composition comprising: (i) an anti-infective agent-loaded biodegradable polymer microspheres; and (ii) a thermoresponsive hydrogel.

The present disclosure relates to a tongue spray containing gymnemic acid together with a form of exogenous ketones. The present disclosure also relates to methods of reducing or eliminating sugar consumption and reducing sugar withdrawal symptoms via administration of such composition to a subject.

A method for treating melanoma or preventing the development of melanoma comprising administration of a composition comprising .sup.64Zn.sub.e(Asp).sub.2 in a therapeutically effective amount. Such administration may be via injection such as intratumoral and/or intravenous injection and may be once a day or more than once a day. A composition for the treatment of or prevention of melanoma comprising .sup.64Zn.sub.e(Asp).sub.2 in a therapeutically effective amount. The composition may be a liquid suitable for injection.

A method for treating melanoma or preventing the development of melanoma comprising administration of a composition comprising .sup.64Zn.sub.e(Asp).sub.2 in a therapeutically effective amount. Such administration may be via injection such as intratumoral and/or intravenous injection and may be once a day or more than once a day. A composition for the treatment of or prevention of melanoma comprising .sup.64Zn.sub.e(Asp).sub.2 in a therapeutically effective amount. The composition may be a liquid suitable for injection.

The invention relates to the veterinary field and, more particularly, non-rinsed compositions comprising an active ingredient obtained from Ophiopogon japonicus, panthenol and saccharide isomerate, for non-human mammals. The invention also relates to a method for treating the coat of non-human mammals by applying said non-rinsed compositions to the coat and/or the skin.

The invention relates to the veterinary field and, more particularly, non-rinsed compositions comprising an active ingredient obtained from Ophiopogon japonicus, panthenol and saccharide isomerate, for non-human mammals. The invention also relates to a method for treating the coat of non-human mammals by applying said non-rinsed compositions to the coat and/or the skin.

Provided herein are oronasal formulations including a cannabinoid and N-L-alpha -asparty-L-phenylalamine 1-methyl ester (APM). Also provided are methods of using the formulations.

The present invention discloses means and methods for enhancing cannabinoids efficacy. The invention relates to invigorating performance of cannabinoid by means of combining compounds to prime the binding cannabinoid receptors and promoting demethylation processes. Specifically, the present invention discloses a plant-based composition configured to enhance a physiological effect of a cannabis-derived compound, wherein said composition comprises a synergistic combination of the cannabis-derived compound, at least one portion of at least one plant comprising a methylating/demethylating active agent, and at least one portion of at least one enhancer plant.

The present invention discloses means and methods for enhancing cannabinoids efficacy. The invention relates to invigorating performance of cannabinoid by means of combining compounds to prime the binding cannabinoid receptors and promoting demethylation processes. Specifically, the present invention discloses a plant-based composition configured to enhance a physiological effect of a cannabis-derived compound, wherein said composition comprises a synergistic combination of the cannabis-derived compound, at least one portion of at least one plant comprising a methylating/demethylating active agent, and at least one portion of at least one enhancer plant.

The present invention discloses means and methods for enhancing cannabinoids efficacy. The invention relates to invigorating performance of cannabinoid by means of combining compounds to prime the binding cannabinoid receptors and promoting demethylation processes. Specifically, the present invention discloses a plant-based composition configured to enhance a physiological effect of a cannabis-derived compound, wherein said composition comprises a synergistic combination of the cannabis-derived compound, at least one portion of at least one plant comprising a methylating/demethylating active agent, and at least one portion of at least one enhancer plant.