The present invention includes compositions and methods for reducing at least one of fasting blood glucose, total cholesterol, LDL cholesterol, VLDL cholesterol, a cholesterol:HDL ratio, triglycerides, or increasing a healthy microbiome comprising a synergistic amount of a fiber blend, a polyphenol blend, and a multivitamin supplement in an amount sufficient to lower at fasting blood glucose, total cholesterol, LDL cholesterol, VLDL cholesterol, a cholesterol:HDL ratio, triglycerides, or increasing a healthy microbiome.

The present invention includes compositions and methods for reducing at least one of fasting blood glucose, total cholesterol, LDL cholesterol, VLDL cholesterol, a cholesterol:HDL ratio, triglycerides, or increasing a healthy microbiome comprising a synergistic amount of a fiber blend, a polyphenol blend, and a multivitamin supplement in an amount sufficient to lower at fasting blood glucose, total cholesterol, LDL cholesterol, VLDL cholesterol, a cholesterol:HDL ratio, triglycerides, or increasing a healthy microbiome.

Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cytotoxic T-cells, resulting from hyperactivation of the immune system. A significant surge of Interleukin-6 (IL-6), TNF-α, and other cytokines are thought to be mediators of this enhanced T-cell activity, and runaway inflammation that are dangerous or fatal to the patient. Example oral formulations dubbed BV-4051 and Artovid-20 provide prophylaxis and treatment of these conditions caused by COVID-19 disease. The example formulations contain plant extracts boosting the human immune system and targeting the detrimental effects of the SARS-CoV-2 virus in its various strains.

Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cytotoxic T-cells, resulting from hyperactivation of the immune system. A significant surge of Interleukin-6 (IL-6), TNF-α, and other cytokines are thought to be mediators of this enhanced T-cell activity, and runaway inflammation that are dangerous or fatal to the patient. Example oral formulations dubbed BV-4051 and Artovid-20 provide prophylaxis and treatment of these conditions caused by COVID-19 disease. The example formulations contain plant extracts boosting the human immune system and targeting the detrimental effects of the SARS-CoV-2 virus in its various strains.

Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cytotoxic T-cells, resulting from hyperactivation of the immune system. A significant surge of Interleukin-6 (IL-6), TNF-α, and other cytokines are thought to be mediators of this enhanced T-cell activity, and runaway inflammation that are dangerous or fatal to the patient. Example oral formulations dubbed BV-4051 and Artovid-20 provide prophylaxis and treatment of these conditions caused by COVID-19 disease. The example formulations contain plant extracts boosting the human immune system and targeting the detrimental effects of the SARS-CoV-2 virus in its various strains.

The present invention provides a method of preventive and/or curative treatment of viral infections caused by viruses of the family Papillomaviridae in a subject by administering a therapeutically effective amount of a composition to the subject, wherein the composition comprises of at least one metal ascorbo-camphorate compound, a physiologically acceptable aqueous solvent, and at least one physiologically acceptable excipient, and wherein the metal ascorbo-camphorate compound is Zinc tetra-ascorbo-camphorate referred to as C14. Further, the present invention provides a pharmaceutical composition directed against viral infections caused by viruses of the family Papillomaviridae, the pharmaceutical composition comprising: (a) one metal ascorbo-camphorate compound; (b) a physiologically acceptable aqueous solvent; and (c) at least one physiologically acceptable excipient, wherein the metal ascorbo-camphorate compound is Zinc tetra-ascorbo-camphorate referred to as C14 as well as its use in the preventive and/or curative treatment of viral infections caused by viruses of the family Papillomaviridae. Also provided are a method for the preparation of the said pharmaceutical composition.

The present invention provides a method of preventive and/or curative treatment of viral infections caused by viruses of the family Papillomaviridae in a subject by administering a therapeutically effective amount of a composition to the subject, wherein the composition comprises of at least one metal ascorbo-camphorate compound, a physiologically acceptable aqueous solvent, and at least one physiologically acceptable excipient, and wherein the metal ascorbo-camphorate compound is Zinc tetra-ascorbo-camphorate referred to as C14. Further, the present invention provides a pharmaceutical composition directed against viral infections caused by viruses of the family Papillomaviridae, the pharmaceutical composition comprising: (a) one metal ascorbo-camphorate compound; (b) a physiologically acceptable aqueous solvent; and (c) at least one physiologically acceptable excipient, wherein the metal ascorbo-camphorate compound is Zinc tetra-ascorbo-camphorate referred to as C14 as well as its use in the preventive and/or curative treatment of viral infections caused by viruses of the family Papillomaviridae. Also provided are a method for the preparation of the said pharmaceutical composition.

The present invention provides a method of preventive and/or curative treatment of viral infections caused by viruses of the family Papillomaviridae in a subject by administering a therapeutically effective amount of a composition to the subject, wherein the composition comprises of at least one metal ascorbo-camphorate compound, a physiologically acceptable aqueous solvent, and at least one physiologically acceptable excipient, and wherein the metal ascorbo-camphorate compound is Zinc tetra-ascorbo-camphorate referred to as C14. Further, the present invention provides a pharmaceutical composition directed against viral infections caused by viruses of the family Papillomaviridae, the pharmaceutical composition comprising: (a) one metal ascorbo-camphorate compound; (b) a physiologically acceptable aqueous solvent; and (c) at least one physiologically acceptable excipient, wherein the metal ascorbo-camphorate compound is Zinc tetra-ascorbo-camphorate referred to as C14 as well as its use in the preventive and/or curative treatment of viral infections caused by viruses of the family Papillomaviridae. Also provided are a method for the preparation of the said pharmaceutical composition.

The invention relates to a method for producing, amongst other things, amino-acid and/or hydroxycarboxylic-acid metal chelates, a solvent-free mixture of at least one metal oxide, metal hydroxide, metal carbonate or oxalate, and the solid organic acid is subjected to intensive mechanical stress. According to the invention, this is done in that the reaction partners are introduced in particle form into a fluid stream of a fluid-bed countercurrent mill operating without grinding elements, wherein mechanical activation of at least one of the reaction partners is effected by collision processes within a reaction chamber formed in a region of the fluid stream, and a solid body reaction to form the metal chelate is triggered. The novel method operates very energy-efficiently and with a high specific yield. It leads to a product having compact particles in the small, single-digit micrometer range having a comparatively narrow particle sizc distribution and a large surface. The product is homogenous and very pure. Thermal loading or decomposition of the organic chelate ligands, in particular of the amino acids, is likewise avoided, as are contaminants from milling and grinding element abrasion.

The invention relates to a method for producing, amongst other things, amino-acid and/or hydroxycarboxylic-acid metal chelates, a solvent-free mixture of at least one metal oxide, metal hydroxide, metal carbonate or oxalate, and the solid organic acid is subjected to intensive mechanical stress. According to the invention, this is done in that the reaction partners are introduced in particle form into a fluid stream of a fluid-bed countercurrent mill operating without grinding elements, wherein mechanical activation of at least one of the reaction partners is effected by collision processes within a reaction chamber formed in a region of the fluid stream, and a solid body reaction to form the metal chelate is triggered. The novel method operates very energy-efficiently and with a high specific yield. It leads to a product having compact particles in the small, single-digit micrometer range having a comparatively narrow particle sizc distribution and a large surface. The product is homogenous and very pure. Thermal loading or decomposition of the organic chelate ligands, in particular of the amino acids, is likewise avoided, as are contaminants from milling and grinding element abrasion.