Patent classifications
A61K31/592
HORMONE D (VITAMIN D) AND ITS DERIVATIVES FOR THE TREATMENT AND PREVENTION OF CANCER
Hormone D (vitamin D) and its derivatives are of the class of secosteroids, compounds derived from a steroid in which there has been a ring cleavage. Humans produce Vitamine D in the skin by photosynthesis, during exposure the sunlight emitting ultraviolet radiation in the narrow band of 290 to 315 nm, from 7-dehydrocholesterol and, consequently, vitamin D is an steroid hormone rather than a true vitamin. 7-Dehydrocholesterol is located in the dermal fibroblast and epidermal keratinocytes. The treatment of several nonmelanoma skin cancers with an oral intake of hormone D.sub.3 (vitamine D.sub.3), at a moderate daily dose resolved all of them completely.
HORMONE D (VITAMIN D) AND ITS DERIVATIVES FOR THE TREATMENT AND PREVENTION OF CANCER
Hormone D (vitamin D) and its derivatives are of the class of secosteroids, compounds derived from a steroid in which there has been a ring cleavage. Humans produce Vitamine D in the skin by photosynthesis, during exposure the sunlight emitting ultraviolet radiation in the narrow band of 290 to 315 nm, from 7-dehydrocholesterol and, consequently, vitamin D is an steroid hormone rather than a true vitamin. 7-Dehydrocholesterol is located in the dermal fibroblast and epidermal keratinocytes. The treatment of several nonmelanoma skin cancers with an oral intake of hormone D.sub.3 (vitamine D.sub.3), at a moderate daily dose resolved all of them completely.
Use of paricalcitol in the treatment of inflammatory anaemia
The present invention discloses the use of paricalcitol, a synthetic Vitamin D analogue, in the treatment of inflammatory anaemia, preferably in combination with erythropoeisis-stimulating agents. The use of paricalcitol in the treatment of said pathology is associated with a reduced requirement for erythropoeisis-stimulating agents, with optimised iron absorption and with an increase in plasma erythropoietin levels in said patients. The present invention also discloses pharmaceutical compositions that comprise paricalcitol in combination with erythropoeisis-stimulating agents and pharmaceutically acceptable excipients, in addition to the use thereof as drugs in the treatment of inflammatory anaemia.
Use of paricalcitol in the treatment of inflammatory anaemia
The present invention discloses the use of paricalcitol, a synthetic Vitamin D analogue, in the treatment of inflammatory anaemia, preferably in combination with erythropoeisis-stimulating agents. The use of paricalcitol in the treatment of said pathology is associated with a reduced requirement for erythropoeisis-stimulating agents, with optimised iron absorption and with an increase in plasma erythropoietin levels in said patients. The present invention also discloses pharmaceutical compositions that comprise paricalcitol in combination with erythropoeisis-stimulating agents and pharmaceutically acceptable excipients, in addition to the use thereof as drugs in the treatment of inflammatory anaemia.
Use of paricalcitol in the treatment of inflammatory anaemia
The present invention discloses the use of paricalcitol, a synthetic Vitamin D analogue, in the treatment of inflammatory anaemia, preferably in combination with erythropoeisis-stimulating agents. The use of paricalcitol in the treatment of said pathology is associated with a reduced requirement for erythropoeisis-stimulating agents, with optimised iron absorption and with an increase in plasma erythropoietin levels in said patients. The present invention also discloses pharmaceutical compositions that comprise paricalcitol in combination with erythropoeisis-stimulating agents and pharmaceutically acceptable excipients, in addition to the use thereof as drugs in the treatment of inflammatory anaemia.
Prenatal Dosage Forms, Methods of Administration and Kits Thereof
Disclosed herein are prenatal dosage forms formulated for different stages of the pregnancy cycle. Also disclosed are methods of administering prenatal dosage forms to a prenatal, pregnant or lactating woman. Further disclosed are kits including prenatal dosage forms.
Prenatal Dosage Forms, Methods of Administration and Kits Thereof
Disclosed herein are prenatal dosage forms formulated for different stages of the pregnancy cycle. Also disclosed are methods of administering prenatal dosage forms to a prenatal, pregnant or lactating woman. Further disclosed are kits including prenatal dosage forms.
Life Extension and Quality of Life Improvement for Humans and Other Mammals
The present invention discloses a system and method for increasing the lifespan and quality of life of human beings and other mammals. This discloses methods for preparing and delivering various health and longevity compositions. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation, misting, nasal spray, suppository, etc. An existing compound known to have capacity for life extending potential, rapamycin, is combined with a non-toxic therapeutic anabolic hormone, e.g., DHEA, and cannabidiol (CBD) to enable absorption and effect. These three compounds work together to dramatically improve both the quality of life in aging humans and other mammals as well as extending the life of humans potentially up to 120 healthy years. One preferred embodiment provides a method for continuous low dose supplementation, e.g., incorporated in or with a daily meal. This invention not only resolves the issue of anti-aging of higher life forms, without toxicity, but provides for an improved method for absorption.
Life Extension and Quality of Life Improvement for Humans and Other Mammals
The present invention discloses a system and method for increasing the lifespan and quality of life of human beings and other mammals. This discloses methods for preparing and delivering various health and longevity compositions. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation, misting, nasal spray, suppository, etc. An existing compound known to have capacity for life extending potential, rapamycin, is combined with a non-toxic therapeutic anabolic hormone, e.g., DHEA, and cannabidiol (CBD) to enable absorption and effect. These three compounds work together to dramatically improve both the quality of life in aging humans and other mammals as well as extending the life of humans potentially up to 120 healthy years. One preferred embodiment provides a method for continuous low dose supplementation, e.g., incorporated in or with a daily meal. This invention not only resolves the issue of anti-aging of higher life forms, without toxicity, but provides for an improved method for absorption.
Multi-Nutrient Composition
A method of improving at least one of the following in an individual: lean mass, muscle strength, cognition, systemic inflammation levels, blood cholesterol levels, blood triglyceride levels and glucose tolerance is provided, comprising administering to the individual a multi-nutrient composition a protein, creatine, vitamin D, calcium and an n-3 fatty acid.