The present invention relates to matrix adhesive patch and its preparation. The present invention specifically relates to an analgesic matrix adhesive patch and its preparation. The present invention more specifically relates to a matrix patch adhesive preparation containing Camphor, Menthol and Methyl salicylate and process for the preparation thereof which delivers predetermined amount of drug continuously through skin and provide the temporary relief of minor aches & pains of muscles & joints associated with; Arthritis, Strains, Bruises & Sprains.

The present invention relates to matrix adhesive patch and its preparation. The present invention specifically relates to an analgesic matrix adhesive patch and its preparation. The present invention more specifically relates to a matrix patch adhesive preparation containing Camphor, Menthol and Methyl salicylate and process for the preparation thereof which delivers predetermined amount of drug continuously through skin and provide the temporary relief of minor aches & pains of muscles & joints associated with; Arthritis, Strains, Bruises & Sprains.

This invention generally relates to pharmaceutical compositions for use in the treatment of pain and inflammation, the prevention and improvement of symptoms of musculoskeletal distress degeneration, including temporary loss of range of motion, temporary inflammation, temporary muscle soreness, and combinations thereof, to assist recovery following exercise and recovery of muscles and joints therefrom, and to provide relief of such symptoms in a mammalian organism, said compositions comprising: (i) an analgesically and anti-inflammatory effective amount of a undenatured cartilage including an isolated native Type II collagen; and (ii) an analgesically and antitussively effective amount of at least one non-steroidal anti-inflammatory agent including aspirin, celecoxib, diclofenac, ibuprofen, indomethacin, naproxen, oxaprozin and piroxicam, or a therapeutically active stereoisomer thereof substantially free of its other stereoisomers; and optionally (iii) a pharmaceutically acceptable amount of at least one excipient.

This invention generally relates to pharmaceutical compositions for use in the treatment of pain and inflammation, the prevention and improvement of symptoms of musculoskeletal distress degeneration, including temporary loss of range of motion, temporary inflammation, temporary muscle soreness, and combinations thereof, to assist recovery following exercise and recovery of muscles and joints therefrom, and to provide relief of such symptoms in a mammalian organism, said compositions comprising: (i) an analgesically and anti-inflammatory effective amount of a undenatured cartilage including an isolated native Type II collagen; and (ii) an analgesically and antitussively effective amount of at least one non-steroidal anti-inflammatory agent including aspirin, celecoxib, diclofenac, ibuprofen, indomethacin, naproxen, oxaprozin and piroxicam, or a therapeutically active stereoisomer thereof substantially free of its other stereoisomers; and optionally (iii) a pharmaceutically acceptable amount of at least one excipient.

The present technology relates to synthesis of resveratrol compositions, in particular to methods of synthesizing resveratrol salicylates such as those formed through the activation of resveratrol and salicylic acid, and cosmetic and pharmaceutical compositions comprising the same.

The present technology relates to synthesis of resveratrol compositions, in particular to methods of synthesizing resveratrol salicylates such as those formed through the activation of resveratrol and salicylic acid, and cosmetic and pharmaceutical compositions comprising the same.

The present invention provides a patch comprising a backing layer and an adhesive agent layer, wherein the adhesive agent layer is non-aqueous, the adhesive agent layer contains nonylic acid vanillylamide and aluminum hydroxide, a content of nonylic acid vanillylamide in the adhesive agent layer is 0.01 to 0.025% by mass based on a total mass of the adhesive agent layer, a content of aluminum hydroxide in the adhesive agent layer is 0.55 to 1.5% by mass based on the total mass of the adhesive agent layer, and a mass ratio of the content of nonylic acid vanillylamide to the content of aluminum hydroxide ((content of nonylic acid vanillylamide):(content of aluminum hydroxide)) in the adhesive agent layer is 1:27 to 1:150.

The present invention provides a patch comprising a backing layer and an adhesive agent layer, wherein the adhesive agent layer is non-aqueous, the adhesive agent layer contains nonylic acid vanillylamide and aluminum hydroxide, a content of nonylic acid vanillylamide in the adhesive agent layer is 0.01 to 0.025% by mass based on a total mass of the adhesive agent layer, a content of aluminum hydroxide in the adhesive agent layer is 0.55 to 1.5% by mass based on the total mass of the adhesive agent layer, and a mass ratio of the content of nonylic acid vanillylamide to the content of aluminum hydroxide ((content of nonylic acid vanillylamide):(content of aluminum hydroxide)) in the adhesive agent layer is 1:27 to 1:150.

Provided is an application of a compound represented by general formula 1 in the preparation of a local anesthetic. The local anesthetic comprises at least a solid portion and a liquid portion that are separated. The solid portion comprises a therapeutically effective amount of the compound represented by general formula 1. The liquid portion is a pharmaceutically acceptable solvent. The solid portion and the liquid portion are mixed when the local anesthetic is used.

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Provided is an application of a compound represented by general formula 1 in the preparation of a local anesthetic. The local anesthetic comprises at least a solid portion and a liquid portion that are separated. The solid portion comprises a therapeutically effective amount of the compound represented by general formula 1. The liquid portion is a pharmaceutically acceptable solvent. The solid portion and the liquid portion are mixed when the local anesthetic is used.

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