Provided is an application of a compound represented by general formula 1 in the preparation of a local anesthetic. The local anesthetic comprises at least a solid portion and a liquid portion that are separated. The solid portion comprises a therapeutically effective amount of the compound represented by general formula 1. The liquid portion is a pharmaceutically acceptable solvent. The solid portion and the liquid portion are mixed when the local anesthetic is used. ##STR00001##

Provided is an application of a compound represented by general formula 1 in the preparation of a local anesthetic. The local anesthetic comprises at least a solid portion and a liquid portion that are separated. The solid portion comprises a therapeutically effective amount of the compound represented by general formula 1. The liquid portion is a pharmaceutically acceptable solvent. The solid portion and the liquid portion are mixed when the local anesthetic is used. ##STR00001##

A method of treating an MS patient with homosalate, octyl salicylate, or a combination is disclosed.

A method of treating an MS patient with homosalate, octyl salicylate, or a combination is disclosed.

Methods of treatment and pharmaceutical formulations configured to treat primary and secondary mitochondrial dysfunction are provided. The methods and treatments use an agonist of AMPK. The agonist activates AMPK to activate ATP-producing pathways and inhibiting ATP-consuming pathways, thus allowing for the alleviation of symptoms associated with mitochondrial dysfunctions.

Methods of treatment and pharmaceutical formulations configured to treat primary and secondary mitochondrial dysfunction are provided. The methods and treatments use an agonist of AMPK. The agonist activates AMPK to activate ATP-producing pathways and inhibiting ATP-consuming pathways, thus allowing for the alleviation of symptoms associated with mitochondrial dysfunctions.

Methods of making polytetrafluoroethylene (PTFE)/polymer composites are disclosed herein. The products can be used in the field of bio- and medical applications, such as for use in artificial blood vessels, vascular grafts, cardiovascular and soft tissue patches, facial implants, surgical sutures, and endovascular prosthesis, and for any products known in the aerospace, electronics, fabrics, filtration, industrial and sealant arts.

Methods of making polytetrafluoroethylene (PTFE)/polymer composites are disclosed herein. The products can be used in the field of bio- and medical applications, such as for use in artificial blood vessels, vascular grafts, cardiovascular and soft tissue patches, facial implants, surgical sutures, and endovascular prosthesis, and for any products known in the aerospace, electronics, fabrics, filtration, industrial and sealant arts.

The subject-matter of the present invention is the use of a therapeutic composition comprising, in an applying carrier, at least one essential oil for relieving muscle and/or joint pain in an animal subject, wherein said composition topically treats an area of the skin of said subject, characterized in that said composition comprises methyl salicylate, which constitutes, with at least one essential oil of the composition containing same in only a small amount or not at all, an active agent within which the rate of transport of the methyl salicylate through the skin is increased by virtue of the oil, which is an essential oil.

The subject-matter of the present invention is the use of a therapeutic composition comprising, in an applying carrier, at least one essential oil for relieving muscle and/or joint pain in an animal subject, wherein said composition topically treats an area of the skin of said subject, characterized in that said composition comprises methyl salicylate, which constitutes, with at least one essential oil of the composition containing same in only a small amount or not at all, an active agent within which the rate of transport of the methyl salicylate through the skin is increased by virtue of the oil, which is an essential oil.