Silver and titanium oxide nanoparticles produced with Fomes fomentarius or Fomitopsis pinicola aqueous extracts and methods for treating bacterial infections or cancer using them.

Silver and titanium oxide nanoparticles produced with Fomes fomentarius or Fomitopsis pinicola aqueous extracts and methods for treating bacterial infections or cancer using them.

Compositions and methods for the treatment of pruritic ani and anal fissures are described. The compositions include one or more of Calamine (USP) or zinc oxide (ZnO), aluminum hydroxide (Al(OH).sub.3) glycerin, and menthol (or any compound which activates the menthol receptor (TRPM8)). The composition does not contain (or contains a limited amount, such as less than 10%) of a hydrocarbon-based pharmaceutical carrier such as petroleum jelly, white petrolatum, mineral oil, hard paraffin, soft paraffin, microcrystalline wax, or ceresine. Methods of treating pruritic ani and anal fissures by topical application(s) of the compositions to affected perianal or anal epidermis are also described.

Compositions and methods for the treatment of pruritic ani and anal fissures are described. The compositions include one or more of Calamine (USP) or zinc oxide (ZnO), aluminum hydroxide (Al(OH).sub.3) glycerin, and menthol (or any compound which activates the menthol receptor (TRPM8)). The composition does not contain (or contains a limited amount, such as less than 10%) of a hydrocarbon-based pharmaceutical carrier such as petroleum jelly, white petrolatum, mineral oil, hard paraffin, soft paraffin, microcrystalline wax, or ceresine. Methods of treating pruritic ani and anal fissures by topical application(s) of the compositions to affected perianal or anal epidermis are also described.

The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer.

The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer.

Micronutrient compositions for treating hair loss, and methods for treating hair loss by periodically administering the compositions. The micronutrients include vitamins, antioxidants, minerals, such as ferrous, calcium, and zinc salts, amino acids, fatty acids, co-enzyme Q10, biotin, omega 3, B-complex, curcumin, colostrum, lactoferrin, N acetyl cysteine, inositol, melatonin, biotin, and the like, and combinations thereof. Careful selection of doses and dosing schedules allows enhancing efficiency, preventing antagonism, reducing side effect and avoiding wastage and overdose of the micronutrients. The components support the activity of the hair growth cycle, and act as building blocks required for hair growth, lack of which can lead to slowing down and arrest of hair growth. They also help maintain inter- and intra-cellular calcium levels, reduce interference with glucose metabolism, gastric irritation and constipation in patients, and promote hair growth, without using Minoxidil or Finasteride.

Micronutrient compositions for treating hair loss, and methods for treating hair loss by periodically administering the compositions. The micronutrients include vitamins, antioxidants, minerals, such as ferrous, calcium, and zinc salts, amino acids, fatty acids, co-enzyme Q10, biotin, omega 3, B-complex, curcumin, colostrum, lactoferrin, N acetyl cysteine, inositol, melatonin, biotin, and the like, and combinations thereof. Careful selection of doses and dosing schedules allows enhancing efficiency, preventing antagonism, reducing side effect and avoiding wastage and overdose of the micronutrients. The components support the activity of the hair growth cycle, and act as building blocks required for hair growth, lack of which can lead to slowing down and arrest of hair growth. They also help maintain inter- and intra-cellular calcium levels, reduce interference with glucose metabolism, gastric irritation and constipation in patients, and promote hair growth, without using Minoxidil or Finasteride.

A preparation method of calcium peroxide-mediated in situ crosslinkable hydrogel as a sustained oxygen-generating matrix, includes: a) reacting a natural or a synthetic polymer with Traut's reagent (TR) in a solvent, and synthesizing a polymer derivative having thiol group in backbone of the polymer derivative; and b) mixing and reacting a solution of the polymer derivative having thiol group with calcium peroxide (CaO.sub.2), and thereby forming a hydrogel, wherein in the step b), disulfide bonds (—S—S) are induced between backbones of the polymer derivative having thiol group attached by decomposition of calcium peroxide (CaO.sub.2), and thereby in situ crosslinking is formed.

Antimicrobially effective compositions comprising lactic acid, salicylic acid, and at least one anionic surfactant are provided. The compositions are effective in controlling pathogen levels, particularly those commonly found on bovine teats to prevent or reduce the incidence of mastitis in lactating cows. In particular, the compositions possess germicidal and/or yeasticidal characteristics. Methods of using the antimicrobial compositions, as a part of a good milking routine, are also provided in which the compositions are applied to bovine teats.