As described below, the present invention features compositions and methods for treating brain and/or behavioral health disorders and their associated symptoms.

As described below, the present invention features compositions and methods for treating brain and/or behavioral health disorders and their associated symptoms.

The present invention provides a composition, preferably a dietary or pharmaceutical composition, comprising or consisting of vitamin(s) (a), and optionally minerals (b), and a pharmaceutically or dietetically suitable carrier such as nutrients DHA and/or EPA (c), encapsulated in a soft gelatine such as a bovine, porcine, vegetable and succinylated gelatine shell, wherein the vitamin(s) include Vitamin C and said Vitamin C is, at least in part, in the form of an ascorbate salt such as, but not limited to, Calcium ascorbate or any other divalent cation salt such as Magnesium ascorbate.

The present invention provides a composition, preferably a dietary or pharmaceutical composition, comprising or consisting of vitamin(s) (a), and optionally minerals (b), and a pharmaceutically or dietetically suitable carrier such as nutrients DHA and/or EPA (c), encapsulated in a soft gelatine such as a bovine, porcine, vegetable and succinylated gelatine shell, wherein the vitamin(s) include Vitamin C and said Vitamin C is, at least in part, in the form of an ascorbate salt such as, but not limited to, Calcium ascorbate or any other divalent cation salt such as Magnesium ascorbate.

Liquid formulations containing picosulfate and magnesium citrate are provided. The compositions can include one or more precipitation inhibitors such as carboxylic acids (e.g., malonic acid), soluble anionic polymers and ammonium salts. The formulations are useful to treat constipation or for the clearance of the bowel prior to X-ray examination, endoscopy or surgery.

Liquid formulations containing picosulfate and magnesium citrate are provided. The compositions can include one or more precipitation inhibitors such as carboxylic acids (e.g., malonic acid), soluble anionic polymers and ammonium salts. The formulations are useful to treat constipation or for the clearance of the bowel prior to X-ray examination, endoscopy or surgery.

The present invention is directed to an antimicrobial shoe insole comprising an antimicrobial composition. The antimicrobial shoe insole has the density from 0.12 to 0.30 g/cm.sup.3, preferably 0.18 to 0.22 g/cm.sup.3, the hardness of the shore C is 28 to 45, the ball rebound rate is ≥65%, and anti-fatigue test (20% compression rate) is over 10,000 times. The antimicrobial shoe insole is formulated to have a sterilization rate over 99.99%, durable, and the mildew resistance index can be zero with no detectable mildew growth.

The present invention is directed to an antimicrobial shoe insole comprising an antimicrobial composition. The antimicrobial shoe insole has the density from 0.12 to 0.30 g/cm.sup.3, preferably 0.18 to 0.22 g/cm.sup.3, the hardness of the shore C is 28 to 45, the ball rebound rate is ≥65%, and anti-fatigue test (20% compression rate) is over 10,000 times. The antimicrobial shoe insole is formulated to have a sterilization rate over 99.99%, durable, and the mildew resistance index can be zero with no detectable mildew growth.

The invention relates to a gel-chewable dosage form comprising a first active pharmaceutical ingredient encapsulated in a lipid material that is embedded in the gel-chewable dosage form and wherein the gel-chewable dosage form comprises at least a second active pharmaceutical ingredient as well as a method of treating a subject suffering from a disease or disorder in the gastro intestinal tract using the gel-chewable dosage form.

The invention relates to a gel-chewable dosage form comprising a first active pharmaceutical ingredient encapsulated in a lipid material that is embedded in the gel-chewable dosage form and wherein the gel-chewable dosage form comprises at least a second active pharmaceutical ingredient as well as a method of treating a subject suffering from a disease or disorder in the gastro intestinal tract using the gel-chewable dosage form.