A61K33/245

BISMUTH(III) COMPOUNDS AND METHODS THEREOF

The present disclosure relates to a pharmaceutical composition comprising: (a) -lactam antibiotics and (b) a metallo--lactamases (MBLs) inhibitor. The inhibitor relates to Bi(III) compounds or the pharmaceutically acceptable salts thereof. The present patent also provides methods of making Bi(III) compounds or the pharmaceutically acceptable salts thereof. Also provided is a method for treating MBLs-producing bacterial infection using a metal replacement mechanism.

BISMUTH(III) COMPOUNDS AND METHODS THEREOF

The present disclosure relates to a pharmaceutical composition comprising: (a) -lactam antibiotics and (b) a metallo--lactamases (MBLs) inhibitor. The inhibitor relates to Bi(III) compounds or the pharmaceutically acceptable salts thereof. The present patent also provides methods of making Bi(III) compounds or the pharmaceutically acceptable salts thereof. Also provided is a method for treating MBLs-producing bacterial infection using a metal replacement mechanism.

BISMUTH(III) COMPOUNDS AND METHODS THEREOF

The present disclosure relates to a pharmaceutical composition comprising: (a) -lactam antibiotics and (b) a metallo--lactamases (MBLs) inhibitor. The inhibitor relates to Bi(III) compounds or the pharmaceutically acceptable salts thereof. The present patent also provides methods of making Bi(III) compounds or the pharmaceutically acceptable salts thereof. Also provided is a method for treating MBLs-producing bacterial infection using a metal replacement mechanism.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS
20240207352 · 2024-06-27 · ·

The present disclosure provides compositions and methods for modulating various mammary' disorders and conditions. The disclosure further provides a therapeutic combination of a composition of at least one casein protein or casein-derived peptide; and a teat seal composition.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS
20240207352 · 2024-06-27 · ·

The present disclosure provides compositions and methods for modulating various mammary' disorders and conditions. The disclosure further provides a therapeutic combination of a composition of at least one casein protein or casein-derived peptide; and a teat seal composition.

Synthesis of Antimicrobial PVP-coated Bismuth Nanoparticles
20240197774 · 2024-06-20 ·

Described herein is a facile, fast, and economical method for the synthesis of BAL-mediated PVP-BiNPs, using basic laboratory instruments and reagents readily available in most laboratories.

Synthesis of Antimicrobial PVP-coated Bismuth Nanoparticles
20240197774 · 2024-06-20 ·

Described herein is a facile, fast, and economical method for the synthesis of BAL-mediated PVP-BiNPs, using basic laboratory instruments and reagents readily available in most laboratories.

INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF

The present disclosure provides compounds useful as inhibitors of SARM1 NADase activity, compositions thereof, and methods of using the same. The present disclosure provides compounds useful for treating a neurodegenerative or neurological disease or disorder, compositions thereof, and methods of using the same.

INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF

The present disclosure provides compounds useful as inhibitors of SARM1 NADase activity, compositions thereof, and methods of using the same. The present disclosure provides compounds useful for treating a neurodegenerative or neurological disease or disorder, compositions thereof, and methods of using the same.

Bismuth(III) compounds and methods thereof

The present disclosure relates to a pharmaceutical composition comprising: (a) -lactam antibiotics and (b) a metallo--lactamases (MBLs) inhibitor. The inhibitor relates to Bi(III) compounds or the pharmaceutically acceptable salts thereof. The present patent also provides methods of making Bi(III) compounds or the pharmaceutically acceptable salts thereof. Also provided is a method for treating MBLs-producing bacterial infection using a metal replacement mechanism.