The present invention provides methods of treating one or more complications of premature birth suffered by premature infants, comprising administering to the premature infant umbilical cord blood stem cells and, optionally, placental stem cells. The present invention also provides methods of combining and administering, and compositions comprising, umbilical cord blood stem cells, particularly autologous cord blood cells, and placental stem cells for the treatment of premature infants.

A nanoparticle comprising chemically modified heparin, wherein the heparin has been chemically modified by attaching hydrophobic moieties to functional groups of the heparin, said functional groups being selected from hydroxy groups and carboxy groups, for use in the treatment or diagnosis of a brain disorder.

A nanoparticle comprising chemically modified heparin, wherein the heparin has been chemically modified by attaching hydrophobic moieties to functional groups of the heparin, said functional groups being selected from hydroxy groups and carboxy groups, for use in the treatment or diagnosis of a brain disorder.

Disclosed is a composition for use in preventing, alleviating, or treating psoriasis containing cimicifugolide A as an active ingredient.

Disclosed is a composition for use in preventing, alleviating, or treating psoriasis containing cimicifugolide A as an active ingredient.

An external dermal composition and a method for beautifying skin are provided. The external dermal composition mainly includes a double nitrosyl-iron complex and a pharmaceutically acceptable additive. The external dermal composition delivers nitric oxide to a user's skin to beautify the skin when applied to the user's skin.

The present invention is directed to an antimicrobial shoe insole comprising an antimicrobial composition. The antimicrobial shoe insole has the density from 0.12 to 0.30 g/cm.sup.3, preferably 0.18 to 0.22 g/cm.sup.3, the hardness of the shore C is 28 to 45, the ball rebound rate is ≥65%, and anti-fatigue test (20% compression rate) is over 10,000 times. The antimicrobial shoe insole is formulated to have a sterilization rate over 99.99%, durable, and the mildew resistance index can be zero with no detectable mildew growth.

The present invention is directed to an antimicrobial shoe insole comprising an antimicrobial composition. The antimicrobial shoe insole has the density from 0.12 to 0.30 g/cm.sup.3, preferably 0.18 to 0.22 g/cm.sup.3, the hardness of the shore C is 28 to 45, the ball rebound rate is ≥65%, and anti-fatigue test (20% compression rate) is over 10,000 times. The antimicrobial shoe insole is formulated to have a sterilization rate over 99.99%, durable, and the mildew resistance index can be zero with no detectable mildew growth.

Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, metal ion-noncovalently bound apotransferrin (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer. Thermal therapy using the sensitizing composition effectively treats cancer without pain or side effects and is thus expected to be widely useful in anticancer treatment as monotherapy, and/or in combination with chemotherapy, radiation therapy, or a combination thereof, ultimately increases the potential to cure cancer.

Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, metal ion-noncovalently bound apotransferrin (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer. Thermal therapy using the sensitizing composition effectively treats cancer without pain or side effects and is thus expected to be widely useful in anticancer treatment as monotherapy, and/or in combination with chemotherapy, radiation therapy, or a combination thereof, ultimately increases the potential to cure cancer.