A61K35/34

METHODS TO IMPROVE CELL THERAPY
20230138484 · 2023-05-04 ·

Methods of treatment are provided herein, including administration of a population cells modified to enforce expression of an E-selectin and/or an L-selectin ligand, the modified cell population having a cell viability of at least 70% after a treatment to enforce such expression.

METHODS TO IMPROVE CELL THERAPY
20230138484 · 2023-05-04 ·

Methods of treatment are provided herein, including administration of a population cells modified to enforce expression of an E-selectin and/or an L-selectin ligand, the modified cell population having a cell viability of at least 70% after a treatment to enforce such expression.

CARDIOMYOCYTE PURIFICATION METHOD
20230136878 · 2023-05-04 ·

A method for producing a cell population containing cardiomyocytes, including (1) a step of bringing a receptor-type tyrosine kinase inhibitor (excluding EGF receptor inhibitors) into contact with a cell population containing cardiomyocytes or cardiac progenitor cells, and other cells, the cell population being obtained by culturing pluripotent stem cells in a medium for cardiomyocyte differentiation, and (2) a step of culturing the cell population is provided by the present invention.

TISSUES CONTAINING SEMICONDUCTOR NANOMATERIALS AND METHODS OF PREPARING AND USING THE SAME
20170369847 · 2017-12-28 ·

Provided herein are tissues containing semiconductor nanomaterials and methods of preparing and using the same.

TISSUES CONTAINING SEMICONDUCTOR NANOMATERIALS AND METHODS OF PREPARING AND USING THE SAME
20170369847 · 2017-12-28 ·

Provided herein are tissues containing semiconductor nanomaterials and methods of preparing and using the same.

Artificial cells and delivery devices for use in tissue engineering, and related methods

Provided herein is a drug delivery device and composition, such as a particle, comprising conditioned medium. Also provided herein is a method of preparing polymeric particles for release of conditioned medium. Further, a tissue growth scaffold comprising particles for release of conditioned medium is provided.

Artificial cells and delivery devices for use in tissue engineering, and related methods

Provided herein is a drug delivery device and composition, such as a particle, comprising conditioned medium. Also provided herein is a method of preparing polymeric particles for release of conditioned medium. Further, a tissue growth scaffold comprising particles for release of conditioned medium is provided.

PROCESSES FOR PRODUCING STABLE EXOSOME FORMULATIONS

The invention encompasses methods for generating stable exosome formulations and encompasses stable exosome formulations. The exosome formulations encompass stable liquid exosome formulations and stable lyophilized exosome formulations. In some embodiments, the exosome formulations can be generated by ultrafiltration and diafiltration. The exosome formulations can be suitable for administration to a human.

PROCESSES FOR PRODUCING STABLE EXOSOME FORMULATIONS

The invention encompasses methods for generating stable exosome formulations and encompasses stable exosome formulations. The exosome formulations encompass stable liquid exosome formulations and stable lyophilized exosome formulations. In some embodiments, the exosome formulations can be generated by ultrafiltration and diafiltration. The exosome formulations can be suitable for administration to a human.

BIOCOMPATIBLE IMPLANTS COMPRISING ENGINEERED ENDOTHELIAL CELLS

The present invention involves implants suitable for surgical implantation into subjects. In some embodiments the implants comprise a biocompatible scaffold material and blood vessels containing engineered endothelial cells—such as E4ORF1+ engineered endothelial cells or engineered endothelial cells that express certain marker molecules. The present invention provides implants, methods for preparing such implants, and methods of treatment utilizing such implants.