The present disclosure relates to the treatment of a skin condition in a subject, including but not limited to hyperhidrosis, comprising applying to the skin of the subject a first composition derived from one or more sponges, and a second composition comprising one or more botulinum toxins. Also provided are compositions for use in the treatment of a skin condition in a subject, including but not limited to hyperhidrosis, comprising a first composition and a second composition, wherein (a) the first composition comprises Spongilla; and (b) the second composition comprises one or more botulinum toxins. Also provided are kits, including kits for the treatment of a skin condition in a subject including but not limited to hyperhidrosis, comprising a first composition and a second composition, wherein the first composition comprises Spongilla, and the second composition comprises one or more botulinum toxins.

The present disclosure relates to the treatment of a skin condition in a subject, including but not limited to hyperhidrosis, comprising applying to the skin of the subject a first composition derived from one or more sponges, and a second composition comprising one or more botulinum toxins. Also provided are compositions for use in the treatment of a skin condition in a subject, including but not limited to hyperhidrosis, comprising a first composition and a second composition, wherein (a) the first composition comprises Spongilla; and (b) the second composition comprises one or more botulinum toxins. Also provided are kits, including kits for the treatment of a skin condition in a subject including but not limited to hyperhidrosis, comprising a first composition and a second composition, wherein the first composition comprises Spongilla, and the second composition comprises one or more botulinum toxins.

The present invention relates to a coral composite extract, a composition including the same and a method of producing the same. The coral composite extract includes at least two briarane-type diterpenoid compounds from corals of Briareum violaceum, B. excavatum and B. stechei, thereby being applied as an effective ingredient of a skin external use composition, a cosmetic composition and a medicinal composition.

The present invention relates to a coral composite extract, a composition including the same and a method of producing the same. The coral composite extract includes at least two briarane-type diterpenoid compounds from corals of Briareum violaceum, B. excavatum and B. stechei, thereby being applied as an effective ingredient of a skin external use composition, a cosmetic composition and a medicinal composition.

Herbal composition for treatment and management of Thyroid dysfunction and method of preparation are disclosed herein. The disclosed composition including herbs and bhasmas may be used to treat Thyroid dysfunction and associated complications such as Hashimoto's thyroiditis, hyperthyroidism, hypothyroidism, Goiter, Thyrotoxicosis, Graves' disease, autoimmune thyroiditis etc. The method disclosed herein may be used as the main line of treatment or as supportive medication.

Herbal composition for treatment and management of Thyroid dysfunction and method of preparation are disclosed herein. The disclosed composition including herbs and bhasmas may be used to treat Thyroid dysfunction and associated complications such as Hashimoto's thyroiditis, hyperthyroidism, hypothyroidism, Goiter, Thyrotoxicosis, Graves' disease, autoimmune thyroiditis etc. The method disclosed herein may be used as the main line of treatment or as supportive medication.

The present invention provides a method for the cultivation of glial cells from Aurelia aurita Medusa primary cultures. There are no present methods providing instructions on the cultivation of glial cells from any invertebrates. Through the creation of this new method, the growth of glial cells from Aurelia aurita is now possible and the production of new medicines for the treatment of myelination disorders will be faster and easier leading to these medicines becoming more readily available to the consumers who need them.

The present invention relates to a method for modulating angiogenesis in a subject in need thereof, which comprises administering an effective amount of composition comprising excavatolide B and a pharmaceutically acceptable carrier to the subject.

The present invention relates to a method for modulating angiogenesis in a subject in need thereof, which comprises administering an effective amount of composition comprising excavatolide B and a pharmaceutically acceptable carrier to the subject.

Compositions comprising a citrate salt and a calcium carbonate-containing material, articles-of-manufacturing and kits comprising same and uses thereof for inducing blood coagulation and/or for reducing or arresting hemorrhaging, particularly internal hemorrhaging, are disclosed.