Patent classifications
A61K35/74
SYSTEMS AND METHODS FOR GROWING A BIOFILM OF PROBIOTIC BACTERIA ON SOLID PARTICLES FOR COLONIZATION OF BACTERIA IN THE GUT
The present invention provides a method, wherein the method forms a biofilm, wherein the biofilm comprises a population of at least one bacterial strain attached to particles, wherein the biofilm is configured to colonize a gut of a subject in need thereof for at least five days, when ingested by the subject, the method comprising: a. obtaining a population comprising at least one strain of bacteria; b. inoculating a growth medium containing particles with the population comprising at least one strain of bacteria; c. incubating the particles with the population comprising at least one bacterial strain for a time sufficient for the population of at least one strain of bacteria to attach to the particles; and d. culturing the population comprising at least one strain of bacteria attached to the particles in a growth medium, for a time sufficient to form a biofilm.
SYSTEMS AND METHODS FOR GROWING A BIOFILM OF PROBIOTIC BACTERIA ON SOLID PARTICLES FOR COLONIZATION OF BACTERIA IN THE GUT
The present invention provides a method, wherein the method forms a biofilm, wherein the biofilm comprises a population of at least one bacterial strain attached to particles, wherein the biofilm is configured to colonize a gut of a subject in need thereof for at least five days, when ingested by the subject, the method comprising: a. obtaining a population comprising at least one strain of bacteria; b. inoculating a growth medium containing particles with the population comprising at least one strain of bacteria; c. incubating the particles with the population comprising at least one bacterial strain for a time sufficient for the population of at least one strain of bacteria to attach to the particles; and d. culturing the population comprising at least one strain of bacteria attached to the particles in a growth medium, for a time sufficient to form a biofilm.
METHOD FOR ANTI-AGEING BY USING PARABACTEROIDES GOLDSTEINII AND ITS GLYCOLIPID
The present disclosure provides a method for anti-ageing by using Parabacteroides goldsteinii and its glycolipid. The Parabacteroides goldsteinii and its glycolipid of the present disclosure achieve anti-ageing effects through various efficacy experiments.
METHOD FOR ANTI-AGEING BY USING PARABACTEROIDES GOLDSTEINII AND ITS GLYCOLIPID
The present disclosure provides a method for anti-ageing by using Parabacteroides goldsteinii and its glycolipid. The Parabacteroides goldsteinii and its glycolipid of the present disclosure achieve anti-ageing effects through various efficacy experiments.
Listeria-based compositions comprising a peptide minigene expression system and methods of use thereof
This disclosure provides compositions, including Listeria delivery vectors comprising minigene expression constructs, and methods of using the same for inducing an immune response against an antigen-expressing tumor and for treating the same, and vaccinating against the same in subjects bearing the tumors.
Listeria-based compositions comprising a peptide minigene expression system and methods of use thereof
This disclosure provides compositions, including Listeria delivery vectors comprising minigene expression constructs, and methods of using the same for inducing an immune response against an antigen-expressing tumor and for treating the same, and vaccinating against the same in subjects bearing the tumors.
Treatment of <i>Clostridium difficile </i>infection
Provided herein are compositions and methods for the treatment or prevention of pathogenic infections.
Treatment of <i>Clostridium difficile </i>infection
Provided herein are compositions and methods for the treatment or prevention of pathogenic infections.
Compositions and methods for treating cholestatic disease
The invention provides compositions and methods for use in the treatment and prevention of cholestatic diseases.
Immunomodulatory compositions and methods of use thereof
The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.