Methods for detecting skin sensitization chemical compounds using Nuclear Magnetic Resonance (NMR) spectroscopy and/or a microplate spectrophotometric assay or other spectroscopic methods. The presently disclosed subject matter relates to a method of detecting skin sensitization potential of a test chemical compound using Nuclear Magnetic Resonance (NMR) spectroscopy, microplate spectrophotometry or other spectroscopic methods as stand-alone or in combination.

The present invention refers to the medical field. Particularly, it refers to a method for determining whether an immune response has occurred in subjects who have been infected with- or vaccinated against coronavirus.

The present invention provides novel antigens of an allergy to soybean, methods and kits for diagnosing an allergy to soybean, pharmaceutical compositions comprising such an antigen, soybeans or processed products of soybean in which such an antigen is eliminated, and a tester for determining the presence or absence of a soybean antigen in an object of interest.

This disclosure relates to a tattoo decal containing bacteria that can be applied to skin and function as both a monitoring sensor and a visual indicator. In particular, a temporary tattoo containing a bacteria composite that may be selected or programmed to sense, detect, or otherwise react to a variety of stimuli for use in a variety of applications and industries is disclosed.

The present invention relates to charts, stacks and methods for evaluating skin color of a mammalian subject. The chart may include a substrate and an indicia visible from a first side of the substrate that includes a plurality of images of mammalian skin tones having varying degrees of yellowness, wherein each indicia is correlated with an index value. Also, the present invention relates to packaged topical cosmetic products that include a skin chart as well as to methods for evaluating anti-aging and skin lightening products.

Glucose-sensing luminescent dyes, polymers, and sensors are provided. Additionally, systems including the sensors and methods of using these sensors and systems are provided.

In various embodiments, provided are methods for selecting and formulating compositions for treating and maintaining the quality of skin in a select population, wherein a composition is selected for use in a personal care product based on its demonstrated biological effect to improve skin quality in the population as evidenced by one or more biomarker changes that correlate with improvement as evidenced by one or more objective measurements of skin health in the population.

Methods and apparatus for determining the efficacy of a drug by diagnosing cardiovascular health in a patient by monitoring changes in skin redness levels, which is associated with perfusion and ability of circulatory system to adapt to physical exertion. Color detectors including colorimeters and spectrophotometers may be used to monitor and quantify skin color. Wet run solutions such as acetylcholine solutions may be applied to the skin area being monitored. Skin redness can be monitored during the course of exercise or a stress test, as well as during recovery. Wearable color detector devices can be worn by patients during exercise.

Methods and apparatus for determining the efficacy of a drug by diagnosing cardiovascular health in a patient by monitoring changes in skin redness levels, which is associated with perfusion and ability of circulatory system to adapt to physical exertion. Color detectors including colorimeters and spectrophotometers may be used to monitor and quantify skin color. Wet run solutions such as acetylcholine solutions may be applied to the skin area being monitored. Skin redness can be monitored during the course of exercise or a stress test, as well as during recovery. Wearable color detector devices can be worn by patients during exercise.

The present invention is directed to a kit for evaluating on the skin of a patient the sensitivity to penicillin, comprising (A) a first vial containing a major determinant mixture, the major determinant mixture comprising benzylpenicilloyl polylysine; (B) a second vial containing lyophilized minor determinant mixture, the minor determinant mixture comprising a lyophilized mixture of neutralized (1) penicillin G potassium; (2) penicilloic acid; and (3) penilloic acid; (C) a third vial containing amoxicillin sodium; and (D) instructions for carrying out a method to evaluate on the skin of a patient the sensitivity to penicillin. The present invention is also directed to a method to rule out penicillin allergy using the disclosed kit.