A feed additive for farm animals and poultry is provided, including biomass and/or cultural liquid of the microalgae Chlorella vulgaris together with chlorellin in a titer of 108-1014 CFU per 1 ml of cultural liquid and/or biomass. Related methods are also provided.

The present invention relates to an antibacterial and antioxidant composition containing grape callus culture solution, as an active ingredient, comprising epsilon()-viniferin, delta ()-viniferin, resveratrol, and the like, and, specifically, grape callus, its culture solution, and its extract according to the present invention exhibit no cytotoxicity, have significant antioxidant and antibacterial effect against Propionibacterium acnes, and have remarkable antioxidant and antibacterial effect compared to pure viniferin, in particular, and thus, the grape callus, its culture solution, and its extract can be effectively used as active ingredients in antioxidant and antibacterial compositions.

The present disclosure provides a composition containing a purified population of plant-derived exosome-like nanoparticles isolated from tissue of a vascular plant, wherein the exosome-like nanoparticles comprise a tuned cargo comprising a protein signature and an miRNA signature, wherein the tuned cargo of the plant-derived exosome-like nanoparticles is a result of exposure of the plant to combinations of abiotic stress conditions that cause the plant to modulate its signaling pathways and metabolism to ensure its survival in a challenging environment. The tuned cargo of the plant-derived exosome-like nanoparticles can modulate bioactivities of mammalian cells directly or indirectly. The present disclosure also provides a method for improving appearance of human skin and human hair health, including eyelashes and eyebrows, comprising applying a composition comprising the abiotically stressed plant-derived exosome-like nanoparticles containing the tuned cargo and a carrier; and applying the composition topically.

Described herein are mushroom compositions and methods for treating, prophylaxis of, or ameliorating symptoms of one or more adverse reactions triggered by an infectious disease or condition that increases an anti-inflammatory response in a subject with such compositions. In one aspect the composition comprises an aqueous or solid fraction of a mycelium, a fermented substrate thereof, or a combination thereof optionally combined with one or more buffering agents, ethanol, and water.