A61K2236/13

Method for preparation of pharmacologically-relevant compounds from botanical sources
11135258 · 2021-10-05 ·

In a multi-step process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step of the process provides a low-temperature, robust essential oil/terpene capture that also dehydrates and decarboxylates the starting—fresh raw cannabis—by means of a vacuum-assisted microwave distillation process. By doing the terpene capture under vacuum distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids. The process includes additional steps of: extract cannabinoids from the dehydrated cannabis to produce a crude extract via a supercritical CO2 extraction process; purify crude extract of fats, lipids, plant material; and distill relevant cannabinoids from the purified crude extract via a wiped-film process. Selected terpenes and cannabinoids are then recombined in predetermined proportions to achieve extracts of unusual purity and having targeted therapeutic profiles.

METHOD AND COMPOSITIONS FOR THE USE OF BOTANICAL EXTRACTS IN THE TREATMENT OF VIRAL INFECTIONS

The present disclosure relates generally to the preparation and use of certain botanical extracts and therapeutic compositions for the treatment of viral infections, cancer, pain, itch, and inflammation. The present disclosure generally relates to antiviral compositions, and more specifically to the preparation of botanical extracts and their use in the treatment of viral infections, cancer, pain associated conditions.

PROCESS FOR THE PREPARATION OF A RAW MATERIAL ENRICHED WITH ISOTHIOCYANATES AND POLYPHENOLS

Disclosed is a process for the preparation of moringa (Moringa oleifera Lam.) sprouts by hydroponic cultivation from seed, as well as a process for the preparation of a raw material enriched with isothiocyanates and polyphenols, starting from moringa (Moringa oleifera Lam.) sprouts obtained from seed by the process and/or from the adult plant, and to the raw material obtained by the process.

Recycling cannabinoid extractor
11071761 · 2021-07-27 ·

A process and apparatus for extracting cannabinoids from cannabis plant material plant material and for transporting low concentrations of cannabinoids in a solution of solvent may include a solvent tank, a hopper, and one or more pumps. A plurality of valves may also be incorporated into the invention. Plant material may be soaked, washed, and/or rinsed with a solvent that extracts essential elements from cannabis plant matter. The process may minimally include filling a hopper with plant mater, moving solvent from a solvent tank to the hopper, and moving solvent back to the solvent tank after an extraction. Repeating this process a plurality of times with new plant material increases the concentration cannabinoids in the solvent tank after each time the process is performed.

DHA Enriched Polyunsaturated Fatty Acid Compositions
20210251937 · 2021-08-19 · ·

There is provided a vegetable-based lipid composition comprising very high levels of DHA, together with at least one other long-chain polyunsaturated fatty acid (typically as fatty acid esters). The composition typically contains low levels of EPA and palmitic acid. The composition is obtainable from a single source by conventional processing methods, and has improved stability properties.

Bitter <i>Ganoderma lucidum </i>spore powder and preparation method thereof

Disclosed is a method for preparing bitter Ganoderma lucidum spore powder, and relates to the field of drugs or health care products. The method includes: removing visible impurities from Ganoderma lucidum spores, conducting ice bath and heating extraction, filtering through a microfiltration membrane, sterilizing by drying, and conducting sporoderm disruption to obtain the bitter Ganoderma lucidum spore powder. The preparation method effectively improves the content of the bitter substances in the Ganoderma lucidum spore powder by removing shriveled spores through multiple times of impurity removal and filtration in combination with the manner of conducting sporoderm disruption after extraction. Taking the total Ganoderma lucidum triterpenoids in the Ganoderma lucidum spores as a representative of the bitter substances, the content of the total Ganoderma lucidum triterpenoids can reach 5-8%. Meanwhile, the preparation method can also make the content of Ganoderma lucidum polysaccharides reaching 6-10%.

Substance and method for the treatment of poxvirus
11065289 · 2021-07-20 ·

A substance for poxvirus molluscum infection treatment that includes a mixture of Anacardium occidentale seeds and sunflower oil is disclosed. The mixture is obtained by the washing, drying, and grinding of at least seven Anacardium occidentale seeds. The grinded seeds are then mixed in with at least one cup of sunflower oil. The mixture is then heated under a low temperature for a duration of at least ten minutes until the seeds are in a liquid or semi-liquid state. The temperature is then raised when the mixture begins to change color. The temperature is then lowered once the mixture ceases to produce smoke. The mixture is then strained and poured into sterile bottles which are wrapped in aluminum foil. When applied to a user, the mixture is then placed on a patch which is then placed on an infected area of a user's body.

Process for converting berry and fruit materials to antimicrobially active fractions

The invention relates to process for converting berry and/or fruit materials to fractions comprising bioactive compounds, said process comprising the steps, where at least one berry material or fruit material selected from berries, fruits, by-products, side streams and waste materials originating from berries or fruits, and any combinations thereof is sieved whereby a seed fraction is separated from a skin fraction, the seed fraction is subjected to sanding and a seed coat fraction comprising surface layer of the seeds and a sanded seed fraction comprising the sanded seeds are obtained.

<i>Pennisetum </i>extract, process for manufacturing the same and uses thereof

The present disclosure provides a Pennisetum extract, process for manufacturing the same, and uses thereof for inhibiting differentiation and/or activation of osteoclast, and prevention and/or treatment of osteoporosis.

PROCESS TO ENHANCE THE BIOACTIVITY OF ASHWAGANDHA EXTRACTS
20210113646 · 2021-04-22 ·

The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.