A61K2236/19

Whitening toothpaste capable of effectively removing dental plaque and tartar
11771644 · 2023-10-03 · ·

A whitening toothpaste capable of effectively removing dental plaque and tartar includes cinnamic acid extract, osthole extract, Lactobacillus salivarius fermentation broth, glycerol, sorbitol, propylene glycol, silicon dioxide, sodium carboxymethyl cellulose, sodium lauryl sulfate, sodium fluoride, potassium fluoride or sodium monofluorophosphate and mint powder. In the present invention, the cinnamon and osthole extracting solutions and Lactobacillus salivarius are selected and used for bacteriostatic, tartar removing and whitening effects, fluoride additives are used for removing pigmentation, and dental plaque in a matched manner, and in combination with a toothpaste system, the toothpaste capable of effectively removing dental plaque and tartar is prepared.

FERMENTED ONION COMPOSITION

The invention relates to a fermented onion composition having a dry matter content of at feast 8 wt. %, said composition comprising, per gram of dry matter: a) 0-150 mg of saccharides selected from fructose, glucose, sucrose and combinations thereof; b) 5-250 mg of phenols selected from acid equivalent of gallic acid, acid equivalent of ferulic acid, quercetin, kaempferol and combinations thereof; c) 75-500 mg acid equivalent of organic acid selected from propionic acid, lactic acid, acetic acid and combinations thereof,

The fermented onion composition of the present invention can advantageously be used as an effective, label-friendly food ingredient to increase overall quality of foods.

The invention also provides a method of preparing a fermented onion composition, comprising: providing an onion substrate containing 10-50 wt. % dry matter and 50-90 wt. % water, wherein at least 40 wt. % of the dry matter is derived from onion; inoculating the substrate with a micro-organism selected from lactic acid bacteria, Propionibacterium and combinations thereof; and incubating the inoculated substrate at a temperature in the range of 25-60° C. for at least 12 hours to produce an onion ferment.

Ganoderma lucidum fermented beverage product and method for making the same
11654168 · 2023-05-23 ·

A method for manufacturing a Ganoderma Lucidum fermented beverage product (GLfb) is provided. It has found that Ganoderma lucidum contains high quantity of natural Pyrroloquinoline Quinone (PQQ). Free radicals generated by ischemic or hypoxic conditions have been found to be a significant cause of myocardial damage leading to myocardial death. PQQ has been reported to act as a free radical scavenger. In particular, PQQ has been reported to be effective in neutralizing superoxide and hydroxyl radicals.

Device with compositions for delivery to the lungs, the oral mucosa and the brain

The present invention provides a passive inhaler for use in treating a number of diseases. The inventor has shown that the compositions comprised in the inhaler can be delivered to the lungs and to the brain in pharmacological relevant dosages, to treat a number of diseases in the lungs and the brain. Further, the inhaler is also able to deliver substances to the brain which may enhance transport across the blood brain barrier.

RAW MATERIAL PRODUCTION FROM STICHOPUS VARIEGATUS
20230355685 · 2023-11-09 ·

A method of producing a bioproduct from a sea cucumber wherein the steps of weighing the sea cucumbers, cleaning the sea cucumber, and milling the sea cucumber in a milling machine for creating a sea cucumber pulp may be performed. Further, the processing of the sea cucumber pulp in a multi-step hydrolysis membrane reactor may be completed for the formation of an unfiltered bioproduct. Such a product may need filtering through an ultrafiltration membrane system to obtain a filtered bioproduct. Followed by inactivation of the protease to create a filtered bioproduct, to which drying may then be needed. The final step may be the application of the filtered bioproduct to a relevant industrial use may be described herein.

COMPOSITION FOR PREVENTING OR TREATING SLEEP DISORDERS, CONTAINING ENZYME-TREATED ASHWAGANDHA EXTRACT AS ACTIVE INGREDIENT

The present invention relates to a composition for preventing sleep disorders or insomnia, containing an enzyme-treated Ashwagandha extract as an active ingredient, and specifically, since it was confirmed that in an animal model and a sleep disorder animal model, which were administered an enzyme-treated Ashwagandha extract, sleep latency and awake time during sleep were decreased, sleep time, non-rapid eye movement (NREM) sleep time and δ-waves were increased, and as a result, sleep activity was improved, the enzyme-treated Ashwagandha extract can be used as an active ingredient of a composition for preventing or treating sleep disorders or insomnia.

ANTI-DIABETIC COMPOSITION CONTAINING BEET MIXTURE AS ACTIVE INGREDIENT
20230354862 · 2023-11-09 ·

The present invention relates to an anti-diabetic composition comprising a fermented product obtained by low-temperature aging a mixture of beets, carrots and apples. More specifically, an aged product, obtained by low-temperature aging of a mixture obtained by extracting and blending juices of beets, carrots and apples in a weight ratio of 1.5-3.5:1.5-2.5:4-7, has excellent blood sugar-reducing effects, such as concentration-dependent suppression of α-glucosidase and α-amylase activity, blood sugar reduction, reduction of fructosamime, insulin, HOMA-IR and HOMA-β content in the blood, and reduction of the area of β cells in Langerhans islands in pancreatic tissue, and thus can be useful as an anti-diabetic composition.

PROCESS FOR PRODUCING A HYDROLYSATE OF SCUTELLARIA ROOT, WHICH IS ENRICHED AND STANDARDIZED WITH FLAVONOIDS OF INTEREST, THE HYDROLYSATE OBTAINED BY SUCH A PROCESS, AND COSMETIC AND DERMOCOSMETIC APPLICATIONS OF SUCH A HYDROLYSATE
20230338453 · 2023-10-26 ·

The invention relates to a process for producing a hydrolysate of Scutellaria roots enriched and standardized in flavonoids of interest. The invention also relates to the hydrolysate resulting from such a process, a composition comprising such a hydrolysate, as well as cosmetic and dermocosmetic applications of such a hydrolysate.

DEVELOPMENT OF BIOCONVERSION PROCESS FOR FUNCTIONAL BLACK SOYBEAN POWDER BIOCONVERTED USING ENZYME GROUP DERIVED FROM BACILLUS BACTERIA AND USE THEREOF
20230381259 · 2023-11-30 · ·

The present invention relates to a method for preparing bioconversion powder having various improved physiological activity functions, by treatment with an enzyme solution derived from a Bacillus polyfermenticus strain, and provides a method for preparing bioconversion powder using a fermentation broth of a Bacillus polyfermenticus strain, by confirming that low-molecular-weight amino acids, peptides and various functional ingredients were formed by treating whole soy milk with a fermentation broth mixed with various degrading enzymes and peptide-synthesizing enzymes derived from the Bacillus polyfermenticus strain.

METHOD FOR IMPROVING ENDOMETRIOSIS AND METHOD FOR PRODUCING A MATERIAL USED THEREFOR

A method for improving endometriosis includes administrating a composition containing aglycon type isoflavones and a pharmaceutically acceptable carrier to mammal subject in need of treatment of endometriosis in an amount effective for treating endometriosis, wherein the aglycon type isoflavones are composed of daidzein, genistein, and glycitein.