A61K2236/31

Extracts of <i>Cynara cardunculus </i>and <i>Citrus aurantium bergamia</i>, combinations thereof, and formulations containing them

Disclosed is a combination of extracts of Cynara cardunculus and Citrus bergamia which are useful for the prevention and treatment of hepatic steatosis and other disorders correlated with dyslipidaemic conditions.

Cannabinoids infused coffee beans and raw nuts
11311589 · 2022-04-26 ·

The present disclosure is directed to whole spectrum cannabinoids infused coffee beans or raw nuts and methods of producing the cannabinoids infused coffee beans or raw nuts. The coffee beans or raw nuts are infused in an overall two-step process, in which cannabinoids from a Cannabis species are first infused into coconut oil, which in turn is used to infuse coffee beans or raw nuts with cannabinoids to generate the cannabinoids infused coffee beans or raw nuts.

PREPARATION METHOD OF NON-ESTER TEA POLYPHENOLS RICH IN EGC

The present invention relates to a preparation method of non-ester tea polyphenols rich in EGC. Wall-broken crushed tea leaves are subjected to leaching using endogenous hydrolytic enzymes contained in the tea leaves. The leached solution after filtration and concentration is subjected to refining and purification by mobile leaching-water washing. The purified product is subjected to concentration and drying to obtain a non-ester tea polyphenols product rich in EGC, wherein the content of tea polyphenols is 90-99.5%, the content of EGC is greater than 80%, and the content of ester catechins EGCG+ECG is less than 10%. According to the preparation method of the non-ester tea polyphenols rich in EGC of the present invention, it does not add any exogenous hydrolytic enzyme, so as to avoid the contamination to the product by the exogenous hydrolytic enzyme. Meanwhile, the content of EGC is high, the production process is simplified, and the yield of the product is high, which is conducive to industrial production.

Extraction and purification of cannabinoids
11766466 · 2023-09-26 · ·

An improved method for making cannabinoids from plant material utilizes the following steps. Plant material is contacted with an aqueous alkaline solution containing a hydroxide base and essentially no organic solvents, thereby extracting cannabinoids including carboxylic acids and salts and producing an alkaline extract. Non-soluble plant material is removed from the alkaline extract to produce a clarified alkaline extract. The extracted cannabinoids are decarboxylated and the decarboxylated cannabinoids are crystallized/precipitated from the clarified alkaline extract at a pH greater than 7.

Packaged frozen cubes of cannabis juice purée with added decarboxylated cannabis material
11179332 · 2021-11-23 ·

Packaged frozen cubes of Cannabis juice purée having decarboxylated cannabinoids are provided. First, raw Cannabis material is collected. Next, the Cannabis material is blended with water, fruit juice, or vegetable juice and thickening agent to form Cannabis juice purée. Next, the purée is poured into molds having an identical size and shape. Decarboxylated/non-decarboxylated high concentrate Cannabis extract or decarboxylated Cannabis infusion is added to the molds. Next, the tray is frozen to obtain frozen cubes of Cannabis juice purée. Next, the cubes are removed from the tray and are packaged in a vacuum sealed bag. A dispensary can store the package in a freezer until distribution. The package includes a label describing amounts and types of cannabinoids present in each cube. A consumer opens the package and deposits a desired amount of cubes into a blender along with other ingredients to form a beverage with non-decarboxylated cannabinoids.

WATER-SOLUBLE, FULL-SPECTRUM, CANNABIS COMPLEX AND METHOD OF PRODUCTION
20210346442 · 2021-11-11 ·

Disclosed herein is a process of producing a water-soluble solid including an amino acid-cyclodextrin-cannabinoid complex from extraction of cannabis. The water-soluble solid composition is also disclosed.

Method of treating coronavirus infections

The present application relates to a compositions and methods comprising or expressing a MOMO30 protein derived from Momordica balsamina. The MOMO30 protein is about 30 kDa in size, binds coronavirus S protein, is stable after being autoclaved at 120° C. for 30 min, resists proteolytic cleavage by trypsin, exhibits mannose-sensitive binding to coronavirus spike (S) protein, exhibits hemagglutinin and chitinase activity, is capable of activating and stimulating T cell proliferation, is capable of preventing infection by a coronavirus or alleviating symptoms in coronavirus infected patients and comprises the amino acid sequence of SEQ ID NO: 1. The MOMO30 protein and/or a nucleic acid encoding the same may be used in methods for preventing or treating viral infections by coronaviruses and others.

Bioactive compositions from fruit and methods for their production

The present invention relates to composition comprising a bioactive fractions (ingredients) derived from fruit juice of an Apple (Pyrus malus) produced by processing the fresh fruit of apple under conditions effective to yield a bioactive fraction that is substantially free of protein and patulin. The present invention also relates to compositions having antioxidant and free radical scavenging properties and suitable for topical applications, oral applications and functional drink applications.

ANTI-COCCIDIAL COMPOSITION COMPRISING MANGOSTEEN AND USES THEREOF

The present application relates to an anti-coccidial composition comprising mangosteen, and the uses thereof. The composition comprising mangosteen according to an example has excellent effect of directly killing protozoa which can induce coccidiosis, effect of inhibiting cell penetration by protozoa and/or effect of inhibiting intracellular protozoan proliferation, and has excellent in vivo coccidiosis prevention, relief and therapeutic effects.

SYSTEMS AND METHODS FOR PRODUCING HEMP EXTRACTS AND COMPOSITIONS
20230285484 · 2023-09-14 ·

A method for producing full spectrum hemp extract comprising extracting substances from cannabis-based green material that are soluble in an extraction solvent and collecting an extract that includes the extraction solvent distilling at least a portion of the extraction solvent which results in a concentrate that is not distilled off, removing at least a portion of water soluble substances from the concentrate by partitioning the at least a portion of water soluble substances into an aqueous phase and a remainder of substances from the concentrate into a partitioned concentrate, heating the partitioned concentrate to evaporate the nonpolar solvent and to yield a crude oil, degassing the crude oil by heating it which results in a degassed crude oil, performing a first pass distillation at about 150° C. and collecting a first residue, performing a second and third pass distillation at about 170° C. and about 185° C., and collecting a distillate from same.