Patent classifications
A61K2236/33
STABLE AQUEOUS COMPOSITIONS OF PLANTS EXTRACTS AND METHODS OF MAKING THE SAME
Provided is a process of stabilizing active ingredients of plant materials in an aqueous suspension, the process including: extracting one or more active ingredients of a plant material using an extraction solvent, wherein the extraction of the one or more active ingredients of the plant materials comprises: transferring the plant material into a temperature-controlled reactor; adding the extraction solvent to the temperature-controlled reactor, thereby producing an eluant from the plant material; incubating the eluant at a first selected temperature for a pre-determined duration of time; and running the eluent through a filtration process to obtain an extractant solution filtrate and a separated solid plan material product; encapsulating the one or more active ingredients in one or more nanoparticles; and dispersing the one or more nanoparticles in an aqueous suspension.
ANTI-MICROBIAL SEAWEED EXTRACTS, COMPOSITIONS AND USES THEREOF
The present invention provides a crude extract, fractions and sub-fractions from the seaweed Fucus distichus (FD), method of preparation and its use for inhibiting the growth of microbial cells, particularly bacteria causing acne or nosocomial infections such as MRSA in humans or MRSP in dogs.
APPLICATION OF TRADITIONAL CHINESE MEDICINE COMPOSITION TO PREPARATION OF MEDICINE FOR TREATING OR PREVENTING CORONAVIRUS INFECTION
Application of a traditional Chinese medicine composition to preparation of a medicine for treating or preventing coronavirus infection. The traditional Chinese medicine composition includes: 5-30 parts of herba houttuyniae, 5-30 parts of flos lonicerae, 5-20 parts of radix paeoniae rubra, 3-15 parts of folium artemisiae argyi and 3-15 parts of herba menthae. The traditional Chinese medicine composition has a good effect of treating or preventing coronavirus-related diseases.
COMPOSITIONS DERIVED FROM SALVIA HISPANICA SEEDS
Methods of preparing a composition from chia seeds are provided. Compositions, including compositions prepared by the presently disclosed methods, and methods regarding selecting chia seeds and administering chia seed extracts are also disclosed.
Method for reducing fat accumulation by using tetramethylisoscutellarein
The present disclosure provides an extract of early-harvested Citrus reticulata fruit, and a method for reducing lipid accumulation by using the extract of early-harvested Citrus reticulata fruit. The extract of early-harvested Citrus reticulata fruit includes tetramethylisoscutellarein.
Pharmaceutical composition for preventing or treating neurodegenerative diseases including fermented steam-dried ginseng berry
The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including a fermented steam-dried ginseng berry as an active ingredient. Specifically, the fermented steam-dried ginseng berry may have a high total ginsenoside and polyphenol content, exhibit antioxidant activity, inhibit acetylcholinesterase, improve cognitive function and spatial perception in animal model of dementias, recover acetylcholine expression and inhibit accumulation of amyloid-beta in brain tissue of the animal model of dementias, inhibit brain damage in animal model of dementias, and promote expression of genes related to brain damage in neuronal cell lines, and accordingly, the fermented steam-dried ginseng berry may be used to treat neurodegenerative diseases, improve cognitive function, and protect brain cells.
Compound and method for treating diseases and disorders
Described is a cannabinoid-terpenoid solution (CTS) and method of treating a disease state or condition in animals other than humans via cannabinoid-terpenoid therapy. The CTS includes a unique combination of cannabinoids, terpenoids (terpenes), and a lipophilic carrier to allow safely and effectively treat the animal.
METHOD FOR TRANSFORMING AN ESSENTIAL OIL
The invention relates to a method for transforming an essential oil, an essential oil fraction obtained in said manner, combinations comprising the essential fraction obtained in said manner and an antibiotic or an antifungal and the use thereof as a medicament in particular the use thereof in the prevention or treatment of infectious bacterial or fungal diseases.
Process to enhance the bioactivity of Ashwagandha extracts
The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASES CAUSED BY SARS-COV-2
The present invention relates to a pharmaceutical composition for preventing or treating COVID-19 diseases, comprising an organic solvent extract of Justicia procumbens as an effective ingredient, a pharmaceutical composition for preventing or treating COVID-19 diseases, comprising justicidin-A as an effective ingredient, a pharmaceutical composition for preventing or treating COVID-19 diseases, comprising justicidin-B as an effective ingredient, or a pharmaceutical composition for preventing or treating COVID-19 diseases, comprising 6′ hydroxyl justicidin-B as an effective ingredient, and a food composition thereof for preventing or ameliorating COVID-19 diseases. According to the present invention, an anhydrous ethanol extract of Justicia procumbens, justicidin-A, justicidin-B, and 6′ hydroxyl justicidin-B effectively inhibit SARS-CoV-2 virus, and thus may effectively prevent, treat, or ameliorate diseases caused by SARS-CoV-2 virus.