A61K2236/37

Methods for making botanical extract composition

A method for making a caffeoylquinic composition from a botanical source is disclosed. The method may include chromatographing an extract of biomass on an ion exchange stationary phase and obtaining an eluent comprising a caffeoylquinic composition. The biomass may be Stevia or yerba mate, for example. The caffeoylquinic composition includes one or more of monocaffeoylquinic acid, dicaffeoylquinic acid, and salts of the foregoing.

METHOD FOR EXTRACTING GYMNADENIA CONOPSEA AND RELATED GYMNADENIA CONOPSEA EXTRACT

The present disclosure provides a method for extracting Gymnadenia conopsea(L.)R.Br., which includes the following steps: (1) the root tuber of Gymnadenia conopsea(L.)R.Br. is soaked in water so that it can be fully infiltrated until having been taken as a sample, no white core is observed; (2) the root tuber of Gymnadenia conopsea(L.)R.Br. is ultrafinely comminuted by wet method to obtain a dispersion slurry; (3) additional water is supplemented into the dispersion slurry to obtain diluted dispersion followed by heating and adding neutral protease, and then extraction is carried out through circulation and homogenization by the homogenization pump to obtain extracted material fluid; (4) heat preservation and enzyme inactivation; (5) coarse filtration to obtain a coarse filtrate; and (6) fine filtration to obtain a fine filtrate. The disclosure also provides a related extract of Gymnadenia conopsea(L)R.Br.

METHODS FOR CONTINUOUS EXTRACTION AND PURIFICATION OF A UNIQUE FLAVAN-3-OL EXTRACT FROM IMMATURE WHOLE GRAPE CLUSTERS AND COMPOSITIONS THEREOF
20220160810 · 2022-05-26 ·

The present disclosure provides a novel process for the continuous extraction, purification and production of a flavan-3-ol extract from early harvested whole grape clusters. The final product from this process is particularly rich in monomeric and oligomeric flavan-3-ols and with an unusually high conversion of the final product into flavan-3-ol subunits under acid catalysis conditions. The oligomers and polymers in the final product are frequently referred to as proanthocyanidins in the field of polyphenol chemistry. The disclosure provides a novel process for the production of the final product via a continuous extraction process and with a final product having a unique composition.

SYRINGA PUBESCENS SEED EXTRACT, ITS PREPARATION AND APPLICATION IN ANTIBIOTIC-RESISTANT INFECTIONS

A Syringa microphylla seed extract includes the following components by weight based on a total weight of the Syringa microphylla seed extract: 0.4944-0.7142 mg/g of echinacoside, 6.624-7.617 mg/g of oleuropein, 0.4276-0.6309 mg/g of verbascoside, 3.927-4.684 mg/g of syringin, and 4.505-5.250 mg/g of forsythiaside B. A method of preparing the Syringa microphylla seed extract is disclosed. A composition for treating antibiotic-resistant infections that includes the Syringa microphylla seed extract is also disclosed.

Method and Compositions for Treating Coronavirus Infection

A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin or digoxin is used to treat the viral infection or the disease state of said viral infection.

Cannabis products modified by removing volatile organic compounds and adding volatile unsaturated hydrocarbons

Purified and modified Cannabis products and methods for producing the same. The purified Cannabis product comprises substantially no volatile organic compounds while retaining Total Potential cannabinoid content. The modified Cannabis product comprises a purified Cannabis product modified by at least one added volatile unsaturated hydrocarbon. The modified Cannabis product is formed by extracting a volatile organic compound from a Cannabis raw material to form a purified Cannabis product, and then adding the at least one volatile unsaturated hydrocarbon to the purified Cannabis product to form the modified Cannabis product and cause an enhanced user experience during combustion and inhalation of the modified Cannabis product.

Controlled cannabis decarboxylation for an infused soluble fat product
11738059 · 2023-08-29 · ·

A process for controlling a decarboxylation of acidic cannabinoids for an infused soluble fat product, such as a butter product, is disclosed. In one embodiment for producing a butter product, raw cannabis base material is dried, pulverized, heated, and cooled to produce a decarbed cannabis material. The decarbed cannabis material is mixed with unsalted butter in an about 22:1 to and about 26:1 ratio, by weight, at ambient temperature and pressure, to produce a heterogenous butter material. The heterogenous butter material is canned and subjected to in-container thermal processing, including agitation during the thermal processing. The resulting heterogenous butter material is separated before cooling produces the butter product.

METHODS FOR PRODUCTION OF LOW COST TERPENOIDS, INCLUDING CANNABINOIDS, AND VARIETIES ADAPTED FOR LARGE-SCALE PLANTING AND DENSITY OPTIMIZATION INCLUDING CANNABINOID PRESERVATION
20220152138 · 2022-05-19 ·

According to the invention, there is provided novel hemp Cannabis cultivars with THC content of 0.2% by dry weight and a unique terpene profile. The cultivars exhibit increased CBD content of greater than about 1.07% by weight. The plants also have increased plant height and decreased branching that allows for increased yields of hemp and CBD content per acre. This invention thus relates to the seeds of hemp Cannabis cultivars of the invention, to the plants of hemp Cannabis cultivars of the invention, to plant parts of hemp Cannabis cultivars of the invention, to methods for producing a Cannabis cultivar by crossing the hemp Cannabis cultivars of the invention with another Cannabis cultivar, and to methods for producing a Cannabis cultivar containing in its genetic material one or more backcross conversion traits or transgenes and to the backcross conversion Cannabis plants and plant parts produced by those methods.

COMPOUND COMPOSITION FOR IMPROVING BONE HEALTH AND PREPARATION AND APPLICATION THEREOF

A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.

FUKE QIANJIN CAPSULE AND QUALITY CONTROL METHOD THEREFOR

The present invention discloses Fuke Qianjin Capsules and a quality control method therefor. The capsules are made of Radix Et Caulis Flemingiae, Caulis Mahoniae, Herba Andrographis, Zanthoxylum dissitum Hemsl., Caulis Spatholobi, Radix Angelicae Sinensis, Radix Codonopsis, and Radix Rosa Laevigata as raw materials. Each of the Fuke Qianjin Capsules contains not less than 2.0 mg of Z-ligustilide, and a total amount of andrographolide and dehydroandrographolide is not less than 1.9 mg. A new standard for controlling quality of the Fuke Qianjin Capsules has been established through an analysis of chemical ingredients in the Fuke Qianjin Capsules. This standard adds a variety of core ingredient content to the existing pharmacopoeia standards. According to the Fuke Qianjin Capsules made in this range, the consistency of effects between different batches is more stable. Moreover, the more the types of core ingredients are limited, the more stable the consistency of the drug effect.