Provided is a process including: extracting a first plurality of active ingredients of a first plant material using a first extraction solvent; extracting a second plurality of active ingredients of a second plant material using a second extraction solvent; transferring the first plurality of active ingredients from the first extractant solution filtrate to a carrier solvent; encapsulating the first plurality of active ingredients in one or more nanoparticles; dispersing the one or more nanoparticles in an aqueous suspension; and adding the second eluant from the second plant material to the aqueous suspension.

The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including a fermented steam-dried ginseng berry as an active ingredient. Specifically, the fermented steam-dried ginseng berry may have a high total ginsenoside and polyphenol content, exhibit antioxidant activity, inhibit acetylcholinesterase, improve cognitive function and spatial perception in animal model of dementias, recover acetylcholine expression and inhibit accumulation of amyloid-beta in brain tissue of the animal model of dementias, inhibit brain damage in animal model of dementias, and promote expression of genes related to brain damage in neuronal cell lines, and accordingly, the fermented steam-dried ginseng berry may be used to treat neurodegenerative diseases, improve cognitive function, and protect brain cells.

The invention relates to a method for transforming an essential oil, an essential oil fraction obtained in said manner, combinations comprising the essential fraction obtained in said manner and an antibiotic or an antifungal and the use thereof as a medicament in particular the use thereof in the prevention or treatment of infectious bacterial or fungal diseases.

The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.

The present invention is drawn to a surface functionalized nanoparticle of Tetra-arsenic Hexoxide by carbon- and carbonbased compounds, that are largely mono-dispersed and bi-pyramidal faceted, having presence of silicon, floats on water, storage stable, capable of oral administration for its effect against multiple chronic diseases including cancer.

This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.

Provided is a method for extracting and refining alkaloids from ipecac, comprising: (1) grinding ipecac, adding acidic methanol/ethanol solution for extraction, obtaining an extraction solution A, concentrating under a reduced pressure, and obtaining a concentrated solution B; (2) using reversed-phase polymer filler J for adsorption, and performing desorption by washing with water, collecting a washing solution C, eluting with an alcoholic solution E and collecting a desorption solution D; (3) injecting the washing solution C and the desorption solution D into a preparative high performance liquid chromatograph for separation and purification respectively, to collect a solution G, and a solution H and a solution I respectively; and (4) concentrating the solutions G, H and I, which are then subjected to reversed-phase polymer filler K for adsorption respectively; eluting them respectively after adsorption with an alcoholic solution F; concentrating obtained eluates to dryness; and then performing vacuum drying.

A process for preparing a total extract which is a mixture of a fresh plant matter with a fatty matter includes a. contacting the fresh plant matter which comprises at least 10% of water by weight relative to its total weight before or after desiccation loss, with the fatty matter chosen from hydrogenated oil or fat at a temperature between 50° C. and 180° C.; b. grinding the plant matter-fatty matter mixture at said temperature between 50° C. to 180° C.; and c. recovering a total extract that is solid or liquid at ambient temperature with a concentration of less than or equal to 4% of water by weight relative to the total weight of the total extract. Extracts recovered from such process and treatments using the extracts are also disclosed.

The present invention provides a composition comprising lycopene, one or both of phytoene and phytofluene, and phytosterols, wherein the concentration of lycopene is in the range of 0.3%-2% (w/w) and wherein the weight ratio of said lycopene to one or both of phytoene and phytofluene is in the range of 1:1 to 1:2.5. The invention also encompasses a method for preparing said composition.

The present invention provides a high-content carotenoid compound from Adonis amurensis. The content of the total carotenoid of the carotenoid compound is higher than 95%. The content of all-trans (3S, 3′S)-carotenoid is higher than 80%. The carotenoid crystals have a high purity, and can be used in multiple forms in the fields of a dietary supplement of a human being, a food additive, a feed additive and a cosmetic product. In addition, the present invention also provides a method for manufacturing the compound.