A61K2236/53

NOVEL COMPOSITION
20230089704 · 2023-03-23 · ·

The invention provides a fenugreek extract composition containing at least one of diosgenin, gitogenin, sarsasapogenin, dioscin, protodioscin, pseudoprotodioscin, apigenin or a derivative thereof, luteolin or a derivative thereof, nicotinic acid or a derivative thereof, and kaempferol, or a salt or solvate of any one thereof. Also provided are processes of preparing the extract composition, and nutraceutical and pharmaceutical compositions containing the extract composition.

METHOD OF EXTRACTING ACTIVE INGREDIENTS IN MUSHROOMS
20220339226 · 2022-10-27 ·

A method of extracting active ingredients in mushrooms includes following steps: crushing a mushroom to obtain a crude mushroom crush; mixing the crude mushroom crush with deionized water to obtain a crude crush mixture; adding the crude crush mixture into a subcritical fluid extractor and extracting the crude crush mixture to obtain a crude mushroom extract; centrifuging the crude mushroom extract to harvest a first supernatant and a mushroom residue; mixing the mushroom residue with deionized water and a cellulase enzyme to obtain a reaction mixture; adding the reaction mixture into a high-pressure hydrolysis reactor and extracting the reaction mixture to obtain a hydrolysate; centrifuging the hydrolysate to obtain a second supernatant; and combining the first supernatant and the second supernatant, and then concentrating the combined first and second supernatants to obtain a mushroom extraction solution.

APPLICATION OF TRADITIONAL CHINESE MEDICINE COMPOSITION IN PREPARATION OF DRUGS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION

An application of a traditional Chinese medicine composition in preparing a medicine for treating or preventing coronavirus infection. The traditional Chinese medicine composition is characterized by being prepared from the following raw materials in parts by weight: 5-15 parts of Cornu saigae tataricae or 50-150 parts of goral horns, 10-60 parts of Bulbus Fritillariae Ussuriensis, 15-60 parts of Radix et Rhizoma Rhei, 7-30 parts of Radix scutellariae, 7-30 parts of Lapis Chloriti, 10-50 parts of gypsum fibrosum, 5-20 parts of calculus bovis artifactus, and 15-60 parts of radix glycyrrhizae. The traditional Chinese medicine composition can inhibit 2019-nCoV replication in cells, so that cells infected by 2019-nCoV viruses have no lesion. Therefore, the traditional Chinese medicine composition can treat or prevent coronavirus related diseases.

STABLE NON-AQUEOUS COMPOSITIONS OF PLANTS EXTRACTS AND METHODS OF MAKING THE SAME
20230081296 · 2023-03-16 ·

Provided is a process including: extracting a first plurality of active ingredients of a first plant material using an extraction solvent, wherein the extraction comprises: transferring the first plant material into a temperature-controlled reactor, adding the extraction solvent to the temperature-controlled reactor, thereby producing a first eluant from the first plant material, incubating the first eluant at a first selected temperature for a first duration of time, applying ultrasound waves on the first plant material to expedite the extraction of the first plurality of active ingredients of the first plant material, and running the first eluent through a filtration process to obtain a first extractant solution filtrate and a first separated solid plan material product; encapsulating the first plurality of active ingredients in one or more nanoparticles; and dispersing the first plurality of active ingredients in a non-aqueous suspension.

POST EXTRACTION PURIFICATION OF TERPENES
20230083465 · 2023-03-16 ·

A method of purifying cannabis derived terpenes includes first providing cannabis material having a detectable amount of tetrahydrocannabinolic acid (THCA), adding a solvent to the cannabis material, spinning the cannabis material in a centrifuge to separate crystallized THCA from a high terpene extract. Decarboxilating the THCA with heat to yield tetrahydrocannabinol. The high terpene extract is deposited into a vacuum oven to reduce pressure and volatilize terpenes from the high terpene extract. Next the terpenes are pumped into a cold trap to condense terpenes from the high terpene extract. Next, the condensed terpenes are cooled at a temperature between −50° C. and 0° C. to remove water from the condensed terpenes and yield purified terpenes. The purified terpenes are applied to an edible food product containing decarboxylated tetrahydrocannabinol. In an alternate embodiment, the tetrahydrocannabinol and the purified terpenes are combined or recombined and mixed directly into a precooked edible food product.

OIL EXTRACT OF CANNABIS AND METHOD FOR OBTAINING

The present invention provides for a method for obtaining an oil extract of cannabis. The method includes: (a) contacting cannabis biomass and an edible oil; (b) pressing between a pair of plates to provide spent cannabis and an oil extract of cannabis; and (c) separating the spent cannabis biomass and the oil extract of cannabis.

SYSTEMS AND METHODS FOR PRODUCING HEMP EXTRACTS AND COMPOSITIONS
20230131076 · 2023-04-27 ·

A method for producing full spectrum hemp extract comprising extracting substances from cannabis-based green material that are soluble in an extraction solvent and collecting an extract that includes the extraction solvent distilling at least a portion of the extraction solvent which results in a concentrate that is not distilled off, removing at least a portion of water soluble substances from the concentrate by partitioning the at least a portion of water soluble substances into an aqueous phase and a remainder of substances from the concentrate into a partitioned concentrate, heating the partitioned concentrate to evaporate the nonpolar solvent and to yield a crude oil, degassing the crude oil by heating it which results in a degassed crude oil, performing a first pass distillation at about 150° C. and collecting a first residue, performing a second and third pass distillation at about 170° C. and about 185° C., and collecting a distillate from same.

Antioxidant, antiinflammatory, anti-uvb, anti-allergic, whitening, and anti-wrinkle roselle seed extract

A use of extracts of roselle seeds for preparing a composition of antioxidant, anti-inflammation, anti-UVB, anti-allergy, whitening, moisturizing, and anti-wrinkle, wherein the extracts of the roselle seeds comprise lauric, palmitic, linoleic, oleic, or stearic acids; and a method for preparing the extracts of the roselle seeds comprises steps of: steeping of: extracting a weight ratio of the 12:1 to 20:1 roselle seeds and an ethanol solution with a concentration of 75 to 95%; and steeping the roselle seeds in the ethanol solution to obtain a suspension; and extraction of: the suspension being engaged in an extraction of a continuous and rapid oscillation with an ultrasonic energy with a total energy of 200 to 500W, wherein 1 to 3 hours of the oscillation is one cycle, and a total number of 3 to 5 cycles is lasted, in order to obtain roselle seed crude extracts.

Passion flower seed extract, and cosmetic, pharmaceutical or dermatological compositions containing same

The invention relates to a polyphenolic extract of passion flower seeds, in particular Passiflora incarnata or Passiflora edulis seeds, comprising at least 30 percent by weight polyphenols, expressed as gallic acid equivalent, relative to the weight of the dry extract. The invention also relates to a method for preparing an extract of said type, a composition containing same, and the cosmetic, dermatological or therapeutic use thereof.

Sporoderm-removed <i>Ganoderma lucidum </i>spore powder, granule and preparation method thereof

The present invention discloses sporoderm-removed Ganoderma lucidum spore powder, granule and a preparation method thereof. The sporoderm-removed Ganoderma lucidum spore powder and granule is obtained from sporoderm-disrupted Ganoderma lucidum spore powder through extraction, centrifugation, sporoderm removal, concentration, drying, and pulverization; and in the sporoderm-removed Ganoderma lucidum spore powder and granule, the content of polysaccharides is 10-20 g/100 g, and the content of total triterpenes is 4-10 g/100 g. The present invention has beneficial effects of enhancing immunity and having an auxiliary protection function against radiation hazards. The content of active components is increased by processing the sporoderm-disrupted Ganoderma lucidum spore powder through a special process, such that the human body can more effectively absorb the nutritional components contained in the Ganoderma lucidum spores, and thus the Ganoderma lucidum spore powder gives play to its efficacy better while it is convenient to carry and take the Ganoderma lucidum spore powder.