A61K2236/55

Processes for Extracting Muscimol from Amanita Muscaria
20240165180 · 2024-05-23 ·

Disclosed herein are methods of muscimol extraction from Amanita mushrooms, and more particularly, enhanced muscimol extraction processes from Amanita muscaria, including by distillation, refluxing, and pressing, including processes that increase muscimol content and decrease ibotenic acid content, and which provide liquid and powder extracts useful in preparations for human health.

METHOD OF EXTRACTION OF PROANTHOCYANIDINS COMPOUND FROM PINE BARK OF PINUS ROXBURGHII

A method for synthesis of method of extraction of proanthocyanidins compound from pine barkof Pinus roxburghii comprising the steps: weighing and pulverizing bark to obtain pulverized powder, adding powder with water in steam jacketed rotary extractor to obtain an extract A, adding the residue in the extractor to obtain extract B, processing the second residue to obtain a third residue and an extract C which is further processed to obtain a third residue and extract D, mixing A, B, C, D extract to obtain liquor, subjecting vacuum concentrate and insoluble concentrate and subjecting to spray drying and vacuum drying respectively, sieving the powder followed by sterilization to obtain the Pine Bark Extract and further subjecting to HPLC analysis for proanthocyanidins content and packing the extract into fiber drums with double polybags for storage.

A METHOD FOR REDUCING ANIMAL WEIGHT

The present disclosure relates a method for reducing animal weight, comprising administering to a patient in need thereof a therapeutically or prophylactically effective amount of a mulberry extract. The mulberry extract comprises: 3% to 99% of an alkaloid, 0.2% to 70% of a polysaccharide, 0% to 50% of an amino acid, 0% to 10% of flavone, and 0% to 25% of other components. The mulberry extract of the present disclosure can be used for controlling weight gain, and has a good therapeutic effect on type 2 diabetes with obesity.

Preparation and use of a composition for prevention and mitigation of the effects of radiation

Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise -tocotrienol (GT3) and -tocotrienol (DT3) in ratios wherein the DT3 is predominate. The compositions are useful for radioprotection and radiomitigation in subjects in need thereof.

Lipid Extract of Passiflora Seeds

The invention relates to a lipid extract of the seeds of passion fruit, Passiflora incarnata and/or Passiflora edulis, preferably P. edulis, characterised in that said lipid extract is an oil of passion fruit seeds concentrated in its unsaponifiable fraction, containing between 3 wt. % and 100 wt. % of unsaponifiable matter in relation to the total weight of the extract. The invention also relates to a method for preparing such an extract and to a composition comprising said extract, especially for the use thereof in a dermatological or pharmaceutical composition or as a food.

COMPOSITIONS, KITS AND METHODS FOR TREATING TYPE II DIABETES MELLITUS

Disclosed herein are methods for treating type II diabetes mellitus. In particular, the present invention relates to methods of using an extract of Hedychium coronarium Koenig and a blood glucose reduction agent, to synergistically reduce the blood glucose level of the subject having type II diabetes mellitus.

PURIFIED PSYCHOACTIVE ALKALOID EXTRACTION USING ACIDIFIED ACETONE
20240207336 · 2024-06-27 ·

A solution of extracted psychoactive alkaloids is obtained from psychoactive organisms or an existing extract using a neutral or acidic solvent. Acid extraction of psychoactive compounds from psychoactive organisms results in the dephosphorylated form of psychoactive alkaloids. The solution is basified to deprotonate the alkaloids. It is then subjected to a liquid-liquid extraction with a water-immiscible solvent. The resulting psychoactive organic layer is subjected to evaporation to remove the water-immiscible layer. The resulting residue is dissolved in anhydrous acetone. Anhydrous acetone acidified with a weak acid is added to the solution to cause precipitation of a conjugate salt of the psychoactive alkaloid. The precipitate is dried and standardized to a desired concentration of psychoactive alkaloid by the addition of an excipient. Obtaining the psychoactive alkaloid in the conjugate salt form reduces the amount of non-psychoactive components included in the final extract.

NOVEL POLYPHENOL COMPOUND

Provided is a novel active ingredient derived from locust bean and the use thereof. The present invention is a compound represented by the following formula (I) or a salt thereof, or a solvate thereof.

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Pharmaceutical composition for treating cancer and a method thereof

A pharmaceutical composition containing an anticancer compound, named isopicrinine, isolated from the plant Rhazya Stricta. The pharmaceutical composition may contain a salt, an analog, a derivative, and/or the prodrug of isopicrinine. A method of treating cancer with the pharmaceutical composition is disclosed. A method of extracting isopicrinine is also disclosed.

Cultivation, Processing, and Synthesis of Cannabidiols
20190134122 · 2019-05-09 ·

The process described below is a method of making tinctures starting with extraction of a full spectrum oil from a biomass, then activating the cannabinoids in the full spectrum oil, finally formulating tinctures using the activated full spectrum oil.

Optional additional steps of winterization, distillation, and isolation increase the purity of the resulting product.