Patent classifications
A61K2236/55
PROCESS FOR PURIFICATION OF MITRAGYNINE FROM CRUDE EXTRACT
The present invention discloses a process for purification of Mitragynine or preparation of purified Mitragynine salt from crude Mitragynine extract for the pharmaceutical preparations. More particularly, the present invention discloses purification of Mitragynine or preparation of purified Mitragynine salt using polar aprotic solvents.
Method For Extracting And Purifying Broad-Spectrum Cannabis Oil From Industry Hemp
A method for extracting broad-spectrum cannabis oil from industry hemp includes the following steps: the hemp leaves, flowers drying, crushing to obtain the material powder, the material powder was extracted by ethanol with concentration value of 60-95%(V/V) to get extract, then do the process of concentration, decarboxylation, using short-range molecular distillation to remove impurities, distillation liquid winterization, pressure filtration to remove wax, filter solution into the column to remove impurities, purification, separation. The purified ethanol chromatographic solution to be concentrated in order to remove alcohol and water product namely the broad-spectrum hemp oil, this method may obtain the product of tetrahydrocannabinol (THC) content can control below 0.1%, the product safety is high, completely satisfies the industrial production.
FORSYTHIA SUSPENSA LEAF EXTRACT AND USE THEREOF FOR INCREASING ABUNDANCE OF AKK IN INTESTINAL TRACTS
Disclosed are a preparation method for a Forsythia suspensa leaf extract and a use of the extract for increasing the abundance of AKK in intestinal tracts, which relate to the technical field of medicine. The preparation method for the Forsythia suspensa leaf extract includes: taking Forsythia suspensa leaves, adding a solvent at 90? C. or more for 10 to 40 minutes, filtering and then adding an extractant for extraction to obtain a first product; filtering the first product, taking a supernatant, adsorbing, eluting, and concentrating under reduced pressure to obtain an extract, and freeze-drying to obtain a second product; and dissolving the second product in water, carrying out chromatography, then eluting, collecting an eluate, concentrating under reduced pressure, and freeze-drying into a powder form to obtain the Forsythia suspensa leaf extract.
NOVEL PHENYLPROPANOID COMPOUND
Provided is a novel active ingredient derived from locust bean and the use thereof. The present invention is a compound represented by the following formula (I) or a salt thereof, or a solvate thereof.
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METHOD FOR CULTIVATION OF HYBRID MINT PLANT DESIGNATED 14-27-71 FOR PRODUCTION OF ESSENTIAL OIL COMPOSITION
A hybrid mint plant characterized by an essential oil composition profile, methods of cultivating the hybrid mint plant, and methods of producing an essential oil composition with the essential oil composition profile using the hybrid mint plant are disclosed.
METHOD FOR CULTIVATION OF HYBRID MINT PLANT DESIGNATED 14-41-16 FOR PRODUCTION OF ESSENTIAL OIL COMPOSITION
A hybrid mint plant characterized by an essential oil composition profile, methods of cultivating the hybrid mint plant, and methods of producing an essential oil composition with the essential oil composition profile using the hybrid mint plant are disclosed.
5-deoxy-irilin B Having Angiotensin-I-converting enzyme Inhibition Activity derived from Salicornia SPP. and Composition Containing the Same
A compound having antihypertensive activity, especially 5-deoxy-irilin B having angiotensin-I-converting enzyme inhibition activity, derived from Salicornia SPP., a salty sauce containing the same, and a composition for the prevention and treatment of hypertension containing the same are provided. The Salicornia SPP.-derived salty sauce having superior sensory and functional properties can be produced through cutting or grinding and then hydrolyzing of Salicornia SPP. alone, thus increasing the amounts of polyphenols, which is effective in the treatment of hypertension, and glutamic acid, which is responsible for a savory taste; through purification, thus improving sensory properties such as removal of unpleasant tastes and odors and decoloration; and through concentration under reduced pressure, thus exhibiting both a savory taste and a salty taste, and can also be efficiently utilized as functional foods and medications for the prevention of hypertension and cardiovascular disease, and contains large amounts of organic nutrients and is thus nutritionally useful.
A METHOD FOR MANUFACTURING SPECIAL EXTRACTS FROM SYMPHYTUM
A method for producing a special extract from symphytum includes the steps of: preparing a suspension system from symphytum; differential precipitation of mucopolysaccharides in the suspension system, wherein the differential precipitation includes the following steps: first differential mucous precipitation of high molecular weight mucopolysaccharides as a first deposit in the suspension system, separating of the first deposit and an extraction residue as raffinate and obtaining of a first extract phase; second differential mucous precipitation of low molecular weight mucopolysaccharides as a second deposit from the first extract phase, separating of the second deposit and obtaining of a second extract phase; selective removal of pyrrolizidine alkaloids from the second deposit and/or the second extract phase; and combining of the second deposit, in particular the second deposit cleansed of pyrrolizidine alkaloids, and the second extract phase, in particular the second extract phase cleansed of pyrrolizidine alkaloids, to form the special extract.
APPARATUS FOR PREPARATION OF PHARMACOLOGICALLY-RELEVANT COMPOUNDS FROM BOTANICAL SOURCES
In a system and process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step provides a low-temperature, robust essential oil/terpene capture that also dehydrates and decarboxylates the starting productfresh raw cannabisby means of a vacuum-assisted microwave distillation process. By doing the terpene capture under vacuum distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids. The system includes an oil/water separator configured to prevent leakage of ambient air into the system.
Preparation and Use of a Composition for Prevention and Mitigation of the Effects of Radiation
Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise -tocotrienol (GT3) and -tocotrienol (DT3) in ratios wherein the DT3 is predominate. The compositions are useful for radioprotection and radiomitigation in subjects in need thereof.