A61K2800/75

Biphase chemical peel

A biphasic leave-on skin peel composition, being light-weight, with a pleasing feel upon application, with little to no skin irritation and discomfort. The composition includes at least one of each of alpha and beta hydroxy acids and high content of non-water miscible oil and is present from at least 20% by weight based on the total weight of the composition. The oily and water phases may be present in equal amounts (about 1:1). The composition includes water and alcohol as solvents in the water phase and may include phenylethyl resorcinol and other optional additives, may be devoid or essentially free of surfactant.

Stable silk protein fragment compositions

A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.

Stable silk protein fragment compositions

A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.

ALCOHOL CONTAINING NON-ANTIMICROBIAL CLEANSING COMPOSITION

A non-antimicrobial cleansing composition is disclosed comprising from about 10.0 wt. % to less than about 40 wt. % of one or more C.sub.1-C.sub.8 alcohols; about 0.5 wt. % to about 10.0 wt. % of at least one primary surfactant; 0 wt. % to about 10.0 wt. % of at least one secondary surfactant, with the primary and secondary surfactants having an HLB value greater than 8; a pH adjusting agent; and water. The composition does not achieve a microbial kill level greater than 2.0 log.

Agent for use for inflammatory conditions of mucous membranes
11278566 · 2022-03-22 ·

The present invention relates to an agent comprising anion-exchange groups that are suitable for adsorbing bacterial lipopolysaccharides (LPS) and/or lipoteichoic acids (LTA), for use in the prevention and/or treatment of inflammatory conditions and/or diseases of the oral cavity or in the vaginal region. The present invention also relates to a pharmaceutical composition that comprises an agent of this kind and can adhere to mucosa.

TOPICAL SCALP COMPOSITION

The present disclosure relates to topical scalp care compositions that may be used as leave-on treatments and comprise one or more actives useful for treating symptoms of itch, redness, flaking, and dryness of the scalp. The present disclosure further relates to systems and methods of treating symptoms of itch, redness, flaking, and dryness of the scalp using such topical scalp care compositions.

ALCOHOL CONTAINING LOW-WATER CLEANSING COMPOSITION

A low-water cleansing composition is provided that includes 5.0 wt. % to less than 40 wt. % of one or more C.sub.1-C.sub.8 alcohol, at least 10.0 wt. % of a mixture of two or more surfactants, at least 0.05 wt. % of a pH adjuster; and water, the concentrations being based on a total weight of the low-water cleansing composition.

ALCOHOL CONTAINING NON-ANTIMICROBIAL CLEANSING COMPOSITION

A non-antimicrobial cleansing composition is disclosed comprising from about 10.0 wt. % to less than about 40 wt. % of one or more C.sub.1-C.sub.8 alcohols; about 0.5 wt. % to about 10.0 wt. % of at least one primary surfactant; 0 wt. % to about 10.0 wt. % of at least one secondary surfactant, with the primary and secondary surfactants having an HLB value greater than 8; a pH adjusting agent; and water. The composition does not achieve a microbial kill level greater than 2.0 log.

COMPOUNDS FOR PREVENTING AND TREATING SKIN OR MUCOSAL AFFECTIONS HAVING AN INFLAMMATORY COMPONENT

The present invention concerns the use of selected compounds in a cosmetic skincare treatment or in the treatment of certain skin, scalp or mucosal diseases. The invention also provides a composition for topical use incorporating a pharmaceutically or cosmetically effective amount of a compound for preventing or treating skin or mucosal diseases having an inflammatory component or for reducing the redness or irritation of skin or mucosae.

TOPICAL COMPOSITIONS FOR REDUCING THE EFFECTS OF AGING
20210308026 · 2021-10-07 · ·

The present invention comprises ternary compositions of tamibarotene and/or ammonium lactate in Pemulen for treatment of effects of aging.