A Halobacillus trueperi TCI66207 strain, deposited in Non-profit Private Entity Food Industry Research and Development Institute (Deposit number: BCRC910961). The H. trueperi TCI66207 strain has one or more of the following function: improving skin cell mitochondrion activity, promoting skin cell proliferation, maintaining skin corneum layer completeness, increasing expression of cornifin (Keratin14) and/or hyaluronic acid synthase (HAS3) genes and promoting hyaluronic acid production.

The present invention relates to gentiopicroside free Gentiana acaulis and/or Gentiana septemfida extracts. Furthermore, it relates to cosmetic compositions comprising such gentiopicroside free Gentiana acaulis or Gentiana septemfida extract, as well as mixtures thereof.

Disclosed are compositions and methods for their use for reducing tumor necrosis factor alpha (TNF-) and/or vascular endothelial growth factor (VEGF) production in skin cells by topically applying to skin in need thereof, a composition comprising an effective amount of Opuntia ficus-indica tuna, Opuntia ficus-indica nopales, or both, or extracts thereof, to reduce TNF- or VEGF production in skin cells.

The present invention relates to a deodorant composition comprising an oxazolidine- or, a thiazolidine-carboxylic acid compound, a cosmetic carrier and optionally a fragrance. The invention also relates to a manufacturing process for the deodorant composition, a method of treating malodour and a method of screening deodorant actives as well as inhibiting a Staphylococcus hominis C-S -lyase.

Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.

Provided is a hair growth-promoting composition comprising: 100 parts by weight of a stem cell culture solution obtained from a culture medium of mesenchymal stem cells which have been subcultured two or more times; 0.001 to 0.1 parts by weight of zinc; 5 to 50 parts by weight of a panthenol based compound; and 0.0001 to 0.1 parts by weight of a water-soluble vitamin, wherein it is sprayed or applied on the scalp to promote hair growth. Said hair growth-promoting composition may have an excellent effect and improve economical efficiency in treating alopecia due to a simple delivery method of the composition.

A cosmetic method for modulating pigmentation in a subject includes administering a modulator of angiotensin-converting enzyme 2 (ACE2 modulator) to the subject. The ACE2 modulator can be an inhibitor of angiotensin-converting enzyme 2 (ACE2 inhibitor), in which case, the ACE2 inhibitor can be administered to increase pigmentation in the subject. The ACE2 modulator can also be an activator of angiotensin-converting enzyme 2 (ACE2 activator), in which case the ACE2 activator can be administered to decrease pigmentation in the subject. The treatment of inflammatory skin disease can also be achieved by inhibition of angiotensin-converting enzyme 2.

This invention relates to the use of Lactobacillus delbrueckii to elicit a plant cell of an Iridaceae and the use of these elicited cells in treating sensitive skins.

Compositions and methods are disclosed herein for inducing (up-regulating) the expression of sulfotransferases in the hair follicles, e.g., the scalp. Increasing sulfotransferase is beneficial for metabolizing pro-drugs that require sulfonation to be activated, e.g., minoxidil sulfate is the active metabolite of minoxidil. A method for combining the compositions described herein with topical minoxidil to enhance minoxidil treatment for androgenetic alopecia is described. Additional methods and compositions include the use of retinoid X receptor agonists, retinoic acid receptor agonists, and nuclear receptor agonists in an RXR-NR heterodimer. Additional methods and compositions include the use of a topical solution containing an alkalinizing agent or an alkalinizing agent used with a penetration enhancer for up-regulating the sulfonating capacity of hair bearing skin, hair follicles, and/or keratinocyte cells. In addition, compositions and methods for increasing or decreasing the growth rate of hair follicles is disclosed by altering the intracellular pH.

In one embodiment, the present invention provides a personal care composition, comprising: (i) a compound of Formula (1) at a concentration from 0.0001 wt % to 20 wt % of the composition;

##STR00001## wherein R is selected from the group consisting of C.sub.15-C.sub.23 conjugated dienes, C.sub.15-C.sub.23 hydroxylated mono unsaturated alkenes, and C.sub.15-C.sub.23 hydroxylated alkanes; wherein R1 is selected from the group consisting of H, C.sub.1-C.sub.4 alkyl, CH.sub.2OH, CH.sub.2(CH.sub.3)OH, [CH.sub.2].sub.4NH.sub.2, CH.sub.2CO.sub.2H, [CH.sub.2].sub.2CO.sub.2H,

##STR00002## wherein R3 is CO.sub.2H; CH.sub.2CO.sub.2H; CH.sub.2CH.sub.2CO.sub.2H; ; and (ii) a cosmetically acceptable carrier.