Provided are methods for preparing pathogen-inactivated platelet compositions, as well as processing sets and compositions related thereto.

PROCEDURE FOR PRODUCING IMPLANTS WITH A PERSONALISED SURFACE that involves the cleaning/activation of the implant surface by means of plasma technology using oxygen or argon plasma to obtain surfaces with no organic compounds or oxide layers, and the application of a liquid solution that is designed for each patient and contains a single osteoconductive, osteoinductive, antibiotic, antibacterial or probiotic component, or a combination of any of them. The cleaning/activation of the implant surface by means of plasma technology may be carried out in the clinic or in the implant production plant and the liquid solution may be applied in the dental clinic just before the implant placement procedure.

A cleaning, sanitizing or disinfecting scrubbing device includes a body, a non-thermal plasma generator and damp wipe. Generated plasma activates fluid in the wipe. The device may include spacer posts between the body and wipe and a conductive mesh between the body and wipe or embedded in the wipe. Another embodiment includes a reservoir for holding a water-based fluid, a fluid delivery element connected to the reservoir by a tube through which the fluid can flow and a non-thermal plasma generator. The non-thermal plasma generator activates the fluid. In one embodiment the scrubbing device is a mitt. In another embodiment the scrubbing device is a glove.

A method for generating atmospheric pressure cold plasma inside a hand-held unit discharges cold plasma with simultaneously different rf wavelengths and their harmonies. The unit includes an rf tuning network that is powered by a low-voltage power supply connected to a series of high-voltage coils and capacitors. The rf energy signal is transferred to a primary containment chamber and dispersed through an electrode plate network of various sizes and thicknesses to create multiple frequencies. Helium gas is introduced into the first primary containment chamber, where electron separation is initiated. The energized gas flows into a secondary magnetic compression chamber, where a balanced frequency network grid with capacitance creates the final electron separation, which is inverted magnetically and exits through an orifice with a nozzle. The cold plasma thus generated has been shown to be capable of accelerating a healing process in flesh wounds on animal laboratory specimens.

A plasma treatment device (1) designed to treat a surface with a dielectrically impeded plasma, having a base body (3) that has at least one flat treatment side (5) facing the surface to be treated, and having an electrode arrangement (9) that has at least one electrode (7) and having a dielectric that completely covers the at least one electrode (7) in the direction of the surface to be treated, and having a line arrangement comprising at least one high-voltage supply line (13, 13a, 13b), wherein the electrode (7) is connected to the line arrangement and is able to be supplied, via the high-voltage supply line (13, 13a, 13b), with a high-voltage signal able to be applied to the high-voltage supply line (13, 13a, 13b), and having a nub arrangement (15) arranged on the treatment side (5) of the base body (3) and that has a multiplicity of nubs (17), makes it possible to easily combine an effective plasma treatment with an effective mechanical treatment of the surface to be treated in that the at least one electrode (7) of the electrode arrangement (9) extends into at least one nub (17) of the nub arrangement (15).

An array of non-thermal plasma emitters is controlled to emit plasma based on application of an electric current at desired frequencies and a controlled power level. A power supply for an array controller includes a transformer that operates at the resonant frequency of the combined capacitance of the array and the cable connecting the array to the power supply. The power into the array is monitored by the controller and can be adjusted by the user. The controller monitors reflected power characteristics, such as harmonics of the alternating current, to determine initiation voltage of the plasma and/or resonant frequency plasma emitters. The array of non-thermal plasma emitters may be used in therapeutic, diagnostic, and/or medical sanitization applications, including where a non-thermal plasma treatment regimen is prescribed.

System and method for pathogen inactivation with UV-C light (employed by itself or in addition to filtering out particulates rom the flow of air reaching the user) by delivering, into a lightguide portion of the air inactivation chamber of the system, a dose of ultraviolet radiation sufficient for at least one log reduction level of the pathogen while, at the same time, multiply reflecting the light inside the chamber to increase the irradiance of inactivating light several fold (up to 5×, or even up to 8.6×) as compared to that delivered to the chamber.

Disclosed are to a plasma enhancement member, and a plasma supplying apparatus and a medical instrument including the same. The plasma enhancement member includes a coupling part coupled to an apparatus for generating plasma, an enhancement material accommodating part configured to accommodate an enhancement material for enhancing an operation of the plasma, and a plasma discharge part configured to discharge the plasma including the enhancement material.

Nanoparticles are suspended in a fluid medium which is activated using an ultrasonic transducer in contact with the fluid medium. The fluid may be injected into a body cavity and ultrasonically activated to induce a cavitation effect. The body cavity may contain a natural or artificial hard surface, inflamed or with a biofilm harnessing bacteria, such as a bone, joint or implant, as well as the surrounding tissue. In an embodiment, a treatment device may be used before, during or after a procedure such as a minimally invasive or open surgery to disinfect the body cavity via irrigation with liquid containing suspended nanoparticles and ultrasonically activated. The irrigation device may supply the cavity with the liquid and include therein an ultrasonic transducer. The cleaning and disinfecting process may be performed as treatment of infection in absence of another surgical procedure.

This invention relates to a method, process and apparatus for disinfecting and sterilizing all types of surfaces contaminated with microorganisms and toxic substances to render both inactive. Furthermore, this invention relates to both a method and apparatus for disinfecting and/or sterilizing breathable air and then using this air to protect a confined space from external contamination. The apparatus consists of a new ultra-violet (NUV) source that is more effective than mercury based 254 nm light for destroying DNA of virus, bacteria, spores and cists. It is most effective in breaking chemical bonds in toxic gases and Biotoxins that are useful to terrorists. It is combined with other apparatus that remove particulates and byproducts sometimes produced by the NUV source and maintains positive pressure of the confined space so as to prevent the influx of air from outside the protected zone.