An apparatus includes a fluid reservoir, a sterilization member, and a transfer adapter. The sterilization member operably couples to the fluid reservoir. The sterilization member is configured to be transitioned between a first configuration, in which the sterilization member obstructs an inlet surface of the fluid reservoir and maintains the inlet surface in a substantially sterile environment, and a second configuration, in which the inlet surface is unobstructed. The transfer adapter is configured to be placed in fluid communication with a portion of a patient. The transfer adapter is configured to move relative to the sterilization member from a first position to a second position such that a surface of the transfer adapter contacts the sterilization member to transition the sterilization member to the second configuration. The fluid reservoir is placed in fluid communication with the transfer adapter when the transfer adapter is in the second position.

Embodiments of the invention relates to an antimicrobial composition comprising an alkyl pyrazine compound or mixture of compounds selected from the group consisting of 2-isobutyl-3-methylpyrazine, 2-isobutyl-3-methoxypyrazine, 2-isopropylpyrazine, 2-isobutylpyrazine and mixtures of methylpyrazines having one, two and three isopropyl or isobutyl substituents. Further embodiments of the invention relate to uses of alkyl pyrazine compounds, in particular for controlling microbial growth.

The invention discloses a chlorhexidine base and method for producing a solubilized form containing a chlorhexidine base in the presence of amine oxide. The invention is applicable in medicine and results in development of novel antiseptic or disinfectant compositions that have universal effect against all types of microorganisms, including those residing in biofilms, active against Mycobacterium tuberculosis, including strains of poly-resistant MDR, extremely resistant XDR and pan-resistant PDR, bacterial spores, fungi and viruses.

A method, system, and apparatus for sterilization, decontamination, and antimicrobial therapeutic treatment, which may include a dispensing device to cover a person, plant, animal, surface, enclosure, room or other structure or area with an antimicrobial solution. Radiation sources may expose the antimicrobial agent to a certain wavelength of radiation. The combination of the solution and the radiation may create a synergistic reaction that causes an effect greater than the radiation or solution separately. The same reaction creates a residual antimicrobial effect. A container, area or passageway including an dispensing device a solution so that a person, plant, animal or object is covered or saturated with an antimicrobial solution. Exposure to a certain wavelength of radiation creates a residual, synergistic reaction resulting in a supercharged antimicrobial agent that exhibits retained antimicrobial effects that exist longer than previously discovered due to the antimicrobial agent being exposed to the radiation together.

A reprocessing case may be used to assist in reprocessing an instrument, such as an endoscope in an automated reprocessor. The reprocessing case may include various features such that the case may include and be transitioned between a closed configuration, an open configuration, and a disinfection configuration. In particular the reprocessor may transition the case to a disinfection configuration during a reprocessing procedure.

The hand sanitizer holster is a garment. The hand sanitizer holster comprises a belt, a fastening structure, and a plurality of primary holsters. The fastening structure secures the belt to a healthcare worker. The plurality of primary holsters attach to the belt. Each of the plurality of primary holsters contains a chemical container filled with a sanitizer. The sanitizer is an anti-microbial chemical used for cleaning the hands of the healthcare worker. Each holster contained within the plurality of primary holsters is configured such that the sanitizer dispenses from the chemical container without removing the chemical container from the holster. In a second potential embodiment of the disclosure, the hand sanitizer holster further comprises a shoulder harness. The shoulder harness further comprises one or more straps and one or more secondary holsters.

A method of reducing or preventing the transfer of pathogens between individuals interacting on artificial turf comprises treating the various components of the artificial turf with a residual antimicrobial coating composition. Treating the artificial turf comprises moving an artificial turf treatment apparatus over the turf in at least one pass, the apparatus being capable of liberating particles of infill material out from between the plastic blades of grass of the artificial turf and spraying the particles with the residual antimicrobial coating composition while the particles are in the air above the turf.

An apparatus includes a fluid reservoir, a sterilization member, and a transfer adapter. The sterilization member operably couples to the fluid reservoir. The sterilization member is configured to be transitioned between a first configuration, in which the sterilization member obstructs an inlet surface of the fluid reservoir and maintains the inlet surface in a substantially sterile environment, and a second configuration, in which the inlet surface is unobstructed. The transfer adapter is configured to be placed in fluid communication with a portion of a patient. The transfer adapter is configured to move relative to the sterilization member from a first position to a second position such that a surface of the transfer adapter contacts the sterilization member to transition the sterilization member to the second configuration. The fluid reservoir is placed in fluid communication with the transfer adapter when the transfer adapter is in the second position.

A method for treatment of a bacterial infection in a host mammal in need of such treatment or a method of administering to the host mammal an effective amount of a Triazolo(4,5-d)pyrimidine of formula(I):

##STR00001##

wherein R.sup.1 is C.sub.3-5 alkyl optionally substituted by one or more halogen atoms; R.sup.2 is a phenyl group, optionally substituted by one or more halogen atoms; R.sup.3 and R.sup.4 are both hydroxyl; R is XOH, wherein X is CH.sub.2, OCH.sub.2CH.sub.2, or a bond, and wherein when X is a bond, R is OH; or a pharmaceutical acceptable salt, provided that when X is CH.sub.2 or a bond, R.sup.1 is not propyl; when X is CH.sub.2 and R.sup.1 is CH.sub.2CH.sub.2CF.sub.3, butyl or pentyl, the phenyl group at R.sup.2 must be substituted by fluorine; when X is OCH.sub.2CH.sub.2 and R.sup.1 is propyl, the phenyl group at R.sup.2 must be substituted by fluorine.

Methods for continuously inactivating virus during manufacture of a biological product are provided. The methods include steps of (1) combining (a) a composition including a biological product, and (b) a composition including a virus-inactivation reagent, to obtain (c) a treatment composition having a predetermined property for inactivation of a virus, (2) confirming that the treatment composition exhibits the predetermined property, (3) transferring the treatment composition to a treatment vessel that includes an inlet, an outlet, and a static mixer, the transferring occurring at the inlet, (4) incubating the treatment composition in the treatment vessel at a predetermined temperature while the treatment composition flows at a predetermined rate and contacts the static mixer, and (5) collecting the treatment composition from the treatment vessel at the outlet, wherein steps (1) to (5) are carried out continuously. Apparatuses and systems including such a treatment vessel are also provided.