A method and related system for treating a metallic surface in order to eradicate bacteria on the metallic surface using at least three electrodes and in which the metallic surface is one of the electrodes and in which a stimulation voltage is applied to the metallic surface and an accumulated charge is measured. The accumulated charge is compared to a threshold level wherein the stimulation voltage is maintained until the accumulated charge exceeds the threshold level. In at least one version, the metallic surface is that of a surgical implant.

Various embodiments of the present invention relate to, among other things, systems for generating engineered water nanostructures (EWNS) comprising reactive oxygen species (ROS) and methods for inactivating at least one of viruses, bacteria, bacterial spores, and fungi in or on a wound of a subject in need thereof or on produce by applying EWNS to the wound or to the produce.

Various embodiments of the present invention relate to, among other things, systems for generating engineered water nanostructures (EWNS) comprising reactive oxygen species (ROS) and methods for inactivating at least one of viruses, bacteria, bacterial spores, and fungi in or on a wound of a subject in need thereof or on produce by applying EWNS to the wound or to the produce.

The present disclosure provides a coating apparatus and method for applying a coating of a therapeutic agent, comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, a thermal source for vaporizing the therapeutic agent, and a vacuum source in fluid communication with the device compartment.

The present disclosure provides a coating apparatus and method for applying a coating of a therapeutic agent, comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, a thermal source for vaporizing the therapeutic agent, and a vacuum source in fluid communication with the device compartment.

Methods and systems for sanitization of liquid solutions and food products are provided. In some embodiments, methods are provided for treating a food product or food product preparation or packaging surface to reduce microbial content, comprising contacting the food product or food product preparation or packaging surface with a chlorinated nanobubble solution comprising electrolyzed water. In some embodiments, methods are provided for reducing the growth of bacteria and reversing the growth of biofilm in a water system, comprising chlorinating source water and passing the chlorinated source water through a low zeta potential crystal generator. In some embodiments, methods are provided for purifying water, comprising chlorinating the water and passing the chlorinated water through a low zeta potential crystal generator.

A circuit configuration method for improving efficacy of antibacterial lamps, a voltage boost circuit, and an antibacterial lamp are provided. The voltage boost circuit includes a primary side, a first secondary side, and a second secondary side. An electromagnetic induction occurs between the first secondary side and the primary side to generate a first high voltage, and the first secondary side includes a first connecting terminal and a first grounding terminal. The second secondary side is electrically coupled to the first ground terminal, and an electromagnetic induction occurs between the second secondary side and the primary side to generate a second high voltage that is not equal to the first high voltage. The second secondary side includes a second connecting terminal, and the second connecting terminal and the first connecting terminal are configured to be used to connect with a load.

Systems and methods for reducing pathogens near an implant are discussed. In some cases, the methods include reducing contaminants in a portion of a patient that has an implant and that is disposed interior to a closed surface of skin of the patient. The method can further include placing a conduit in the closed surface of skin and flowing an antimicrobial fluid into that portion of the patient to contact the antimicrobial fluid with a surface of the implant and tissue adjacent to the implant. In some cases, the antimicrobial fluid is then removed from the portion of the patient having the implant. As part of this method, biofilm near the implant can be mechanically, ultrasonically, electrically, chemically, enzymatically, or otherwise disrupted. Other implementations are described.

The invention describes a compact device having, in a housing, a chamber which is closable by a flap, one wall of which chamber having at least one first guidance element and at least one first fixation element, as well as two spaced-apart first contact elements which are fixedly connected to electrical connectors of a generator by electrical leads. Further, the device has at least one carrier having at least one second guidance element which, when the carrier is arranged against the wall, engages the first guidance elements and aligns the carrier in a predetermined position with respect to the wall. The carrier has at least one second fixation element that is aligned to match with the at least one first fixation element upon engagement of the first and second guidance elements, such that, when the first and second guidance elements are engaged, the first and second fixation elements are aligned to match one another and can be secured to one another.

Treatment systems, devices, articles, and associated methods of operation for treating open wounds are disclosed herein. In one embodiment, a method includes applying a first material and a second material to be in contact with a surface of the open wound having a water content at the surface and applying a voltage differential to the first and second materials, thereby producing hydrogen peroxide (H2O2) at the surface via an electrochemical reaction between oxygen (O2) in air and water (H2O) in the water content at the surface. The voltage differential is calibrated to correspond to a concentration of the produced hydrogen peroxide in the water content effective in reducing or preventing a bacterial infection at the surface of the open wound.