A medical bandaging product that includes a flexible medical material including an elongate fabric, a reactive system, and microspheres. In certain aspects, a component of the reactive system is homogeneously impregnated into or coated throughout the flexible medical material without being encapsulated in the microspheres such that the reactive system remains stable and non-activated in the absence of an activating agent, and hardens upon activation by exposure to the activating agent to form a rigid, self-supporting structure. In this aspect, the microspheres are homogeneously impregnated into or coated throughout the flexible medical material, the microspheres encapsulate an activating agent and are configured to release the activating agent to form the rigid, self-supporting structure.

Disclosed herein are antimicrobial elastic support bandages including a plurality of warp threads extending along at least a portion of the length thereof and including non-antimicrobial warp regions and antimicrobial warp regions arranged in an alternating fashion across the width thereof, wherein (a) a non-antimicrobial warp region comprises an elastic material that is stretchable in the direction of the length, (b) an antimicrobial warp region comprises (i) a flexible fiber coupled to an antimicrobial metal, and (ii) an elastic material that is stretchable in the direction of the length, wherein the flexible fiber is coupled to the elastic material, and (c) at least a portion of the warp threads are separated by about 3 microns to about 20 microns; and further including a plurality of weft threads extending across at least a portion of the width and comprising a biocompatible material, wherein at least some of the weft threads are separated by about 3 microns to about 20 microns, wherein at least a portion of the warp threads are interwoven with at least a portion of the weft threads.

Disclosed herein are antimicrobial elastic support bandages including a plurality of warp threads extending along at least a portion of the length thereof and including non-antimicrobial warp regions and antimicrobial warp regions arranged in an alternating fashion across the width thereof, wherein (a) a non-antimicrobial warp region comprises an elastic material that is stretchable in the direction of the length, (b) an antimicrobial warp region comprises (i) a flexible fiber coupled to an antimicrobial metal, and (ii) an elastic material that is stretchable in the direction of the length, wherein the flexible fiber is coupled to the elastic material, and (c) at least a portion of the warp threads are separated by about 3 microns to about 20 microns; and further including a plurality of weft threads extending across at least a portion of the width and comprising a biocompatible material, wherein at least some of the weft threads are separated by about 3 microns to about 20 microns, wherein at least a portion of the warp threads are interwoven with at least a portion of the weft threads.

The present technology relates to composites, apparatuses, systems, and methods that are based on a photocurable composite useful for stabilizing, supporting, or otherwise healing an injured limb. The photocurable composite includes a light-curable resin and a filler material, where the light-curable resin includes about 50 vol % to about 99 vol % (based on the volume of the light-curable resin) of an acrylate-functionalized oligomer, wherein the backbone of the oligomer comprises a polyurethane, a polyether, a polyester, or a combination of any two or more thereof; about 1 vol % to about 50 vol % of a radical-reactive diluent; about 0.001 vol % to about 2 vol % of a photoinitiator; and optionally about 0.05 to about 25 vol % of a surface cure protection agent.

The present technology relates to composites, apparatuses, systems, and methods that are based on a photocurable composite useful for stabilizing, supporting, or otherwise healing an injured limb. The photocurable composite includes a light-curable resin and a filler material, where the light-curable resin includes about 50 vol % to about 99 vol % (based on the volume of the light-curable resin) of an acrylate-functionalized oligomer, wherein the backbone of the oligomer comprises a polyurethane, a polyether, a polyester, or a combination of any two or more thereof; about 1 vol % to about 50 vol % of a radical-reactive diluent; about 0.001 vol % to about 2 vol % of a photoinitiator; and optionally about 0.05 to about 25 vol % of a surface cure protection agent.

A glass, glass-ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded by an amorphous shield. The shield serves to protect the internal porous microstructure of the shield while increasing the overall strength of the porous microstructure and improve the flowability of the beads either by themselves or in devices such as biologically degradable putty that would be used in bone or soft tissue augmentation or regeneration. The open porosity present inside the bead will allow for enhanced degradability in-vivo as compared to solid particles or spheres and also promote the growth of tissues including but not limited to all types of bone, soft tissue, blood vessels, and nerves.

A glass, glass-ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded by an amorphous shield. The shield serves to protect the internal porous microstructure of the shield while increasing the overall strength of the porous microstructure and improve the flowability of the beads either by themselves or in devices such as biologically degradable putty that would be used in bone or soft tissue augmentation or regeneration. The open porosity present inside the bead will allow for enhanced degradability in-vivo as compared to solid particles or spheres and also promote the growth of tissues including but not limited to all types of bone, soft tissue, blood vessels, and nerves.

Provided are materials including cell proliferation properties. The materials may include a polymer having incorporated therein a synergistic combination of at least two metal oxide powders, including a mixed oxidation state oxide of a first metal and a single oxidation state oxide of a second metal. The mixed oxidation state oxide may constitute from about 25% wt. to about 75% wt. of the total weight of the synergistic combination of the at least two metal oxide powders. The powders may be incorporated substantially uniformly within the polymer. The ions of the metal powders may be in ionic contact upon exposure of the material to moisture. Further provided are methods for the preparation of the materials and uses thereof, including in skin regeneration processes and cosmetic applications.

A multi-component frame includes a first component made from a rigid structural material and a second component connected to at least an end portion the first component. The first component is constructed from a metal or metal alloy, and the second component is constructed from a material different from the first component. The first and second components form at least part of a length of the multi-component frame.

A multi-component frame includes a first component made from a rigid structural material and a second component connected to at least an end portion the first component. The first component is constructed from a metal or metal alloy, and the second component is constructed from a material different from the first component. The first and second components form at least part of a length of the multi-component frame.