The present invention includes the composition and manufacturing of a product to treat various types of infections, and disease ailments. The invention embodies a disposable absorbent or nonabsorbent article comprising an unbound/freely associating adsorbent porous carbonaceous material for the entrapment and/or treatment of pathogens and adverse biological by-products. The product form includes three dimensional carriers such as tampons, panty liners, incontinence pads, diapers, sanitary towels, swabs, cotton balls, pouches, and/or plugs, which contain adsorbent porous carbonaceous material that effectively reduces and/or eliminates adverse situations sourcing from pathogens and harmful biological by-products, including fungi, bacteria, viruses, and parasites. The article is used to treat yeast infections, vaginitis, sexually transmitted diseases, tooth infections, abscess, nail-bed and cuticle infections, and other ailments by way of internal insertion and/or completely covering of the body cavity, mucous membrane, and/or affected areas, creating a clear and direct path for contact with pathogens and adverse biological by-products.

The present invention includes the composition and manufacturing of a product to treat various types of infections, and disease ailments. The invention embodies a disposable absorbent or nonabsorbent article comprising an unbound/freely associating adsorbent porous carbonaceous material for the entrapment and/or treatment of pathogens and adverse biological by-products. The product form includes three dimensional carriers such as tampons, panty liners, incontinence pads, diapers, sanitary towels, swabs, cotton balls, pouches, and/or plugs, which contain adsorbent porous carbonaceous material that effectively reduces and/or eliminates adverse situations sourcing from pathogens and harmful biological by-products, including fungi, bacteria, viruses, and parasites. The article is used to treat yeast infections, vaginitis, sexually transmitted diseases, tooth infections, abscess, nail-bed and cuticle infections, and other ailments by way of internal insertion and/or completely covering of the body cavity, mucous membrane, and/or affected areas, creating a clear and direct path for contact with pathogens and adverse biological by-products.

An ankle-foot orthosis forming a monolithic structure and include at least two different material components. The first material component has at least one tape layer consisting of a continuous fiber-reinforced thermoplastic composite, and a second polymeric material component surrounds at least in part the tape and includes a thermoplastic material into which the first material component is embedded. A resin material of the first material component is bonded to the second polymeric material component.

An ankle-foot orthosis forming a monolithic structure and include at least two different material components. The first material component has at least one tape layer consisting of a continuous fiber-reinforced thermoplastic composite, and a second polymeric material component surrounds at least in part the tape and includes a thermoplastic material into which the first material component is embedded. A resin material of the first material component is bonded to the second polymeric material component.

Embodiments of the disclosure include compositions and methods for providing an effective amount of activated or unactivated single-cell or spheroid fibroblasts, exosomes from fibroblasts, lysate from fibroblasts, apoptotic bodies from fibroblasts, and/or fibroblast-related products that are comprised in and/or on a substrate, such as a synthetic polymer or biopolymer scaffolding or biologic mesh, thereby generating a material to cover at least one wound and/or at least one burn of an individual.

The invention provides a ready to use biodegradable and biocompatible device and a method for manufacturing thereof. The device of present invention is a novel porous scaffold which can be used as carrier of plurality of therapeutics to quickly stop bleeding and other biomaterial and biomedical application. The scaffold can be directly applied to the spot of the wound and will stop bleeding within no time. The scaffold of the present invention comprises of combined application of air dry and freeze dry method. The scaffold also comprises of excellent ventilations properties and easy removal of the scaffold without causing any extra hemorrhage to the wound.

The invention provides a ready to use biodegradable and biocompatible device and a method for manufacturing thereof. The device of present invention is a novel porous scaffold which can be used as carrier of plurality of therapeutics to quickly stop bleeding and other biomaterial and biomedical application. The scaffold can be directly applied to the spot of the wound and will stop bleeding within no time. The scaffold of the present invention comprises of combined application of air dry and freeze dry method. The scaffold also comprises of excellent ventilations properties and easy removal of the scaffold without causing any extra hemorrhage to the wound.

A device comprising a casing and having an initial configuration, an intermediate configuration, and a final configuration, wherein in the initial configuration the casing contains: a plurality of beads, a rupturable first container containing one or more isocyanates and a rupturable second container containing one or more polyols. In the final configuration the casing is substantially filled by a polyurethane in which the plurality of beads is embedded. In the intermediate configuration the device is transformed from the initial configuration to the final configuration by rupturing the first container and rupturing the second container so that the one or more isocyanates react with the one or more polyols in a reaction that forms the polyurethane. As the polyurethane is formed during the reaction the polyurethane surrounds the plurality of beads. The casing includes one or more vent tubes configured to allow gases formed by the reaction to escape the casing.

A device comprising a casing and having an initial configuration, an intermediate configuration, and a final configuration, wherein in the initial configuration the casing contains: a plurality of beads, a rupturable first container containing one or more isocyanates and a rupturable second container containing one or more polyols. In the final configuration the casing is substantially filled by a polyurethane in which the plurality of beads is embedded. In the intermediate configuration the device is transformed from the initial configuration to the final configuration by rupturing the first container and rupturing the second container so that the one or more isocyanates react with the one or more polyols in a reaction that forms the polyurethane. As the polyurethane is formed during the reaction the polyurethane surrounds the plurality of beads. The casing includes one or more vent tubes configured to allow gases formed by the reaction to escape the casing.

A finger splint for manual therapy according to the present invention comprises: a base sheet made of a metal material and of a certain length and width to surround a finger; a base hole formed through the center of the base sheet in a rhombus shape; a first hole extending through both upper left and right sides of the base hole along a portion of a periphery of the finger; and a second hole extending through both lower left and right sides of the base hole along the periphery of the finger to correspond to the position and size of the first hole. The finger splint for manual therapy according to the present invention has the effect of providing an excellent and comfortable fit on the basis of an ergonomic structure as well as sufficiently ensuring a basic fixing force.