Patent classifications
A61L15/20
Antimicrobial or wound care materials, devices and uses
Disclosed herein are embodiments of a wound care material with a material which is a composite of a matrix component comprising a flexible hydrophilic polymer foam or fiber matrix comprising two matrix faces providing a release face and a reverse face or two release faces, and therebetween a structural matrix framework defining a network of cells having a cell network surface and therein a network of pores or cell openings, and a powder charge component comprising antimicrobial additive or wound care additive, wherein said powder charge is comprised at one said release face or both said faces and/or within said cell network.
ANTIMICROBIAL DRESSING, DRESSING COMPONENTS, AND METHODS
A dressing that includes an absorbent, antimicrobial layer and a bioresorbable layer is disclosed herein. The absorbent, antimicrobial layer may be formed from nonwoven fibers. The bioresorbable layer may include an extracellular polymeric substance-active agent, such as citric acid. At least a portion of the nonwoven fibers may include carboxymethylcellulose fibers and alginate fibers.
Processes for making low volatile tackifier compositions
A tackifier composition comprising at least one thermoplastic hydrocarbon resin and an antioxidant composition is provided; wherein a portion of the volatile organic compounds in the thermoplastic hydrocarbon resin has been removed; wherein the antioxidant composition comprises at least one primary antioxidant and at least one secondary antioxidant; and wherein the levels of individual volatile organic compound monitored in the tackifier composition are less than about 0.5 ppm as measured by GC/MS headspace analysis. Processes for producing the tackifier composition are also provided as well as adhesives comprising the tackifier compositions.
Processes for making low volatile tackifier compositions
A tackifier composition comprising at least one thermoplastic hydrocarbon resin and an antioxidant composition is provided; wherein a portion of the volatile organic compounds in the thermoplastic hydrocarbon resin has been removed; wherein the antioxidant composition comprises at least one primary antioxidant and at least one secondary antioxidant; and wherein the levels of individual volatile organic compound monitored in the tackifier composition are less than about 0.5 ppm as measured by GC/MS headspace analysis. Processes for producing the tackifier composition are also provided as well as adhesives comprising the tackifier compositions.
Superabsorbent polymer composition
A superabsorbent polymer composition exhibiting very improved antimicrobial and deodorizing properties while maintaining basic absorption performance, and can significantly reduce the generation of dust during the application for a process, and thus fulfills both stability and processability and can be usefully applied for hygienic goods such as a diaper and the like. The superabsorbent polymer composition includes: a) superabsorbent polymer particles including a crosslinked polymer of water-soluble ethylenically unsaturated monomers including acid groups, of which at least a part are neutralized, and b) an antimicrobial agent having a controlled particle size, containing a chelating agent including EDTA or an alkali metal salt thereof; a mixture of an organic acid and a silicate-based salt; and an agent for controlling a particle size.
Compositions and methods related to <i>Rhamnus prinoides </i>(GESHO) extract for the inhibition of polymicrobial biofilm formation
Disclosed are compositions comprising Rhamnus prinoides (GESHO) extract or fragments thereof and methods of using Gesho extract for the inhibition of biofilm formation.
Compositions and methods related to <i>Rhamnus prinoides </i>(GESHO) extract for the inhibition of polymicrobial biofilm formation
Disclosed are compositions comprising Rhamnus prinoides (GESHO) extract or fragments thereof and methods of using Gesho extract for the inhibition of biofilm formation.
Antimicrobial medical biomaterial and a method for preparing the same
An antibacterial medical biomaterial includes an acellular small intestinal submucosal matrix material, an antibacterial gel layer located on a surface of the acellular small intestinal submucosal matrix material, and an absorbable fiber layer located on a surface of the antibacterial gel layer. Sulfadiazine silver is on the surface of the acellular small intestinal submucosal matrix material and/or within the acellular small intestinal submucosal matrix material. An absorbable fiber layer to which the sulfadiazine silver is attached, wherein the content of sulfadiazine silver in the absorbable fiber is 1 wt. %˜2 wt. %. The medical biomaterial is usable as an external medicine for treating wound infections relayed by burns or wounds, and for reducing the incidence of infection by using a conventional central venous catheter with a sulfadiazine silver antibacterial coating, so that the medical biomaterial loaded with sulfadiazine silver also has antibacterial activity consistent with sulfadiazine silver.
Antimicrobial medical biomaterial and a method for preparing the same
An antibacterial medical biomaterial includes an acellular small intestinal submucosal matrix material, an antibacterial gel layer located on a surface of the acellular small intestinal submucosal matrix material, and an absorbable fiber layer located on a surface of the antibacterial gel layer. Sulfadiazine silver is on the surface of the acellular small intestinal submucosal matrix material and/or within the acellular small intestinal submucosal matrix material. An absorbable fiber layer to which the sulfadiazine silver is attached, wherein the content of sulfadiazine silver in the absorbable fiber is 1 wt. %˜2 wt. %. The medical biomaterial is usable as an external medicine for treating wound infections relayed by burns or wounds, and for reducing the incidence of infection by using a conventional central venous catheter with a sulfadiazine silver antibacterial coating, so that the medical biomaterial loaded with sulfadiazine silver also has antibacterial activity consistent with sulfadiazine silver.
BIOFILM PENETRATING COMPOSITIONS AND METHODS
Compositions are provided that have at least two of three active ingredients. The active ingredients maybe a salt having a cation N.sup.αC8-C16 alkanoyl-L di-basic amino acid —C1-C4 alkyl ester, a glycerol monoester of a fatty acid and a sugar ester of a fatty acid. The compositions are useful in methods of killing or inhibiting planktonic bacteria or fungi and bacteria or fungi embedded in a biofilm and prevention of biofilm formation on surfaces. The composition may further comprise a hydrogel and a benefit agent such as an antibiotic that can be solubilized by the hydrogel and supplied to the biofilm matrix by the active ingredients of the composition. Devices such as chronic wound coverings coated with the composition are also provided. Methods of preserving products with the composition are also provided.